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公开(公告)号：US07107104B2
公开(公告)日：2006-09-12
申请号：US10448645
申请日：2003-05-30
申请人： Yves Keravel , Jean Paul N'Guyen , Paulus Van Venrooij , Frans L. H. Gielen , Thomas E. Cross, Jr.
发明人： Yves Keravel , Jean Paul N'Guyen , Paulus Van Venrooij , Frans L. H. Gielen , Thomas E. Cross, Jr.
IPC分类号： A61N1/05
CPC分类号： A61N1/0531 , A61N1/0553
摘要： A neural lead and method of treating neurological disorders by stimulation of the cerebral cortex of the brain is provided. The lead is designed for reduction of strain between the lead body and the lead paddle caused by the position of the lead body above the cranium and the lead paddle beneath the cranium. The lead is also designed to include a two dimensional chronic electrode array for better stimulation coverage of the target area of the cerebral cortex. A method of treating a neurological disorder by stimulating the cerebral cortex is also presented.
摘要翻译： 提供了通过刺激脑的大脑皮层治疗神经障碍的神经引导和方法。 引线设计用于减少引线主体和引线板之间的引线引起的引线体在颅骨上方的位置和颅骨下方的引导片之间的应变。 该引线还被设计成包括用于更好地刺激大脑皮层目标区域的覆盖的二维慢性电极阵列。 还提出了通过刺激大脑皮质治疗神经障碍的方法。
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公开(公告)号：US07792591B2
公开(公告)日：2010-09-07
申请号：US11450147
申请日：2006-06-09
CPC分类号： A61M25/0662 , A61N1/0551 , A61N1/0553 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： The disclosure describes an introducer for facilitating implantation of therapy elements into a patient. The introducer has an elongated body that defines a lumen for advancement of a therapy element to an implant site, and includes a curved portion medially located between substantially straight proximal and distal portions. As an example, the shape of the introducer may allow a clinician to more easily, and without substantially damaging surrounding tissue, find the correct tissue depth and follow that tissue depth to the implant site. For example, the introducer may facilitate implantation of a therapy element within or between desired layers of tissue of the patient. In some embodiments, fluid may be injected through the introducer to create a space within the tissue to implant the therapy element. Fluid may also be evacuated through the introducer prior to implantation.
摘要翻译： 本公开描述了一种用于促进将治疗元件植入患者体内的导引器。 引导器具有限定用于使治疗元件前进到植入部位的内腔的细长主体，并且包括中间位于基本上直的近端部分和远端部分之间的弯曲部分。 作为示例，引导器的形状可以允许临床医生更容易地且不会基本上损伤周围的组织，找到正确的组织深度并且将该组织深度跟随到植入部位。 例如，导引器可以有助于将治疗元件植入患者组织的期望的层之内或之间。 在一些实施例中，流体可以通过导引器注入，以在组织内产生植入治疗元件的空间。 在植入之前，流体也可以通过引入器排空。
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公开(公告)号：US07725198B2
公开(公告)日：2010-05-25
申请号：US11742454
申请日：2007-04-30
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0582
摘要： Implantable lead assembly including a lead body, an elongated conductor, a coiled electrode, and a tether line. The lead body maintains the conductor. The electrode is coupled to the conductor, defining proximal and distal ends. The tether line defines a trailing segment and a leading segment terminating in a leading end. The tether line is coupled to the coiled electrode at a point proximal the distal end, and the leading end extends distal the distal end. With this configuration, a pulling force applied to the leading segment is transferred to the electrode at a point proximal the distal end as a pushing force, thereby minimizing an opportunity for overt stretching of the coiled electrode during implantation. The lead assembly can further include a needle connected to the tether line.
摘要翻译： 可植入引线组件，包括引线体，细长导体，线圈电极和系绳。 导体保持导体。 电极耦合到导体，限定近端和远端。 系绳线定义了一个尾部段和一个终端在前端的前导段。 系绳线在靠近远端的点处连接到线圈电极，并且前端延伸到远端。 利用这种构造，作用在前端的拉力作为推力在靠近远端的点转移到电极，从而最小化植入期间线圈电极的明显拉伸的机会。 导线组件还可以包括连接到系绳线的针。
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公开(公告)号：US07537245B2
公开(公告)日：2009-05-26
申请号：US11057666
申请日：2005-02-14
申请人： Thomas E. Cross, Jr.
发明人： Thomas E. Cross, Jr.
IPC分类号： F16L33/00
CPC分类号： A61M39/1011 , A61M2039/1044 , A61M2039/1088
摘要： A connector assembly for interconnecting separate sections of tubing, e.g., catheters, and a method for using the same. Connector assemblies in accordance with embodiments of the present invention may be a two-piece construction having a connector pin and a strain relief device. The strain relief device, in addition to providing secure, substantially leak-free coupling of the tubing sections, may also provide strain relief to the tubing interconnection.
摘要翻译： 一种连接器组件，其用于互连管道的分开部分，例如导管，以及用于使用该导管的方法。 根据本发明的实施例的连接器组件可以是具有连接器销和应变消除装置的两件式结构。 应变消除装置除了提供管道部分的牢固，基本上无泄漏的联接之外，还可以为管道互连提供应变消除。
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公开(公告)号：US07184838B2
公开(公告)日：2007-02-27
申请号：US10957456
申请日：2004-10-01
申请人： Thomas E. Cross, Jr.
发明人： Thomas E. Cross, Jr.
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/05 , A61N1/0551
摘要： An implantable electrical lead having coiled conductors and a method of manufacturing the lead. The method generally comprises: (a) assembling, along an outer surface of inner elongate structure defining an longitudinal axis, at least one elongate conductor and at least one twist ring holding a first portion of the elongate conductor; (b) fixing a second portion of the elongate conductor to the outer surface of the inner elongate structure, the second portion of the elongate conductor being spaced along the length of the elongate conductor; and (c) rotating the twist ring relative to the longitudinal axis of the inner elongate structure to coil the at least one elongate conductor.
摘要翻译： 具有线圈导体的可植入电线和制造铅的方法。 该方法通常包括：（a）沿着限定纵向轴线的内部细长结构的外表面组装至少一个细长导体和至少一个保持细长导体的第一部分的扭转环; （b）将细长导体的第二部分固定到内部细长结构的外表面，细长导体的第二部分沿着细长导体的长度间隔开; 和（c）使所述扭转环相对于所述内部细长结构的纵向轴线旋转以使所述至少一个细长导体线圈。
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公开(公告)号：US06587733B1
公开(公告)日：2003-07-01
申请号：US09500201
申请日：2000-02-08
IPC分类号： A61N105
CPC分类号： H01R13/025 , A61B5/04001 , A61B5/4041 , A61B2562/227 , A61N1/05 , A61N1/0551 , H01R2201/12
摘要： There is disclosed a surgical lead comprising two percutaneous lead bodies bonded together. The inventive lead body results in the equivalent of a surgical lead body with columns of electrodes either adjacent to or offset from each other. A bridge of urethane material is used to bond together the percutaneous lead bodies and still provide suitable flexibility of the lead. The surface of the electrodes may be coated, in part, with a suitable non-conductive coating to effectively direct the electrical stimulation signals toward the targeted stimulation area. Significantly, the resulting lead is sized to fit within a needle having a similar cross-section, thereby permitting the percutaneous implantation of the inventive lead.
摘要翻译： 公开了一种手术引线，其包括结合在一起的两个经皮引线体。 本发明的引线体相当于具有彼此相邻或相互偏移的电极列的手术引线体。 聚氨酯材料桥用于将经皮引线体粘合在一起，并仍然提供铅的合适的柔性。 电极的表面可以部分地涂覆有合适的非导电涂层，以有效地将电刺激信号引导到目标刺激区域。 显着地，所得到的引线的尺寸适合于具有类似横截面的针中，从而允许本发明的引线的经皮植入。
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公开(公告)号：US4141366A
公开(公告)日：1979-02-27
申请号：US852849
申请日：1977-11-18
IPC分类号： A61N1/04
CPC分类号： A61N1/048 , A61N1/0492
摘要： Electrical lead wire connection to a tape electrode is disclosed. Such electrodes are used for transmitting electrical signals through skin. The tape electrode includes a porous substrate material carrying a conductive layer comprised of finely divided silver metal suspended in a "dry" adhesive. An electrical lead wire is connected to the conductive layer of the tape electrode by a flat cover member having the same conductive layer on both sides thereof as is carried by the substrate of the tape electrode. One of the conductive layers of the cover member secures the lead wire to the conductive layer of the tape electrode. The other conductive layer of the cover member intimately contacts the skin along with the conductive layer of the tape electrode to provide for good electrical contact therewith when the tape electrode is applied thereto. The adhesive is normally "dry" and is activated at the time of application by a suitable solvent.
摘要翻译： {PG，1公开了与带状电极的电气引线连接。 这种电极用于通过皮肤传输电信号。 带状电极包括承载由悬浮在{37干{38 {0粘合剂）中的细分银金属构成的导电层的多孔基材。 电导线通过具有与带状电极的基板承载的两侧具有相同导电层的平坦盖构件连接到带状电极的导电层。 盖构件的导电层之一将引线固定到带电极的导电层。 覆盖构件的另一个导电层与带状电极的导电层一起紧密地接触皮肤，以便当将带状电极施加于其时提供与其良好的电接触。 粘合剂通常为{37干{38 {0，在通过合适的溶剂施用时被活化）。
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公开(公告)号：US09084872B2
公开(公告)日：2015-07-21
申请号：US12869891
申请日：2010-08-27
CPC分类号： A61M25/0662 , A61N1/0551 , A61N1/0553 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： The disclosure describes an introducer for facilitating implantation of therapy elements into a patient. The introducer has an elongated body that defines a lumen for advancement of a therapy element to an implant site, and includes a curved portion medially located between substantially straight proximal and distal portions. As an example, the shape of the introducer may allow a clinician to more easily, and without substantially damaging surrounding tissue, find the correct tissue depth and follow that tissue depth to the implant site. For example, the introducer may facilitate implantation of a therapy element within or between desired layers of tissue of the patient. In some embodiments, fluid may be injected through the introducer to create a space within the tissue to implant the therapy element. Fluid may also be evacuated through the introducer prior to implantation.
摘要翻译： 本公开描述了一种用于促进将治疗元件植入患者体内的导引器。 引导器具有限定用于使治疗元件前进到植入部位的内腔的细长主体，并且包括中间位于基本上直的近端部分和远端部分之间的弯曲部分。 作为示例，引导器的形状可以允许临床医生更容易地且不会基本上损伤周围的组织，找到正确的组织深度并且将该组织深度跟随到植入部位。 例如，导引器可以有助于将治疗元件植入患者组织的期望的层之内或之间。 在一些实施例中，流体可以通过导引器注入，以在组织内产生植入治疗元件的空间。 在植入之前，流体也可以通过引入器排空。
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公开(公告)号：US08204607B2
公开(公告)日：2012-06-19
申请号：US11450148
申请日：2006-06-09
IPC分类号： A61N1/36
CPC分类号： A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/36071 , A61N1/37211
摘要： The disclosure describes an implantable medical lead for delivering stimulation to a patient. Electrodes may be located on two or more surfaces of the lead to, for example, selectively deliver stimulation to one or more tissue layers within the patient. The lead may be implanted within or between intra-dermal, deep dermal, or subcutaneous tissue layers, and may be used to, for example, deliver peripheral nerve field stimulation to treat pain experienced by the patient at the site at which the lead is implanted. The lead may comprise a paddle lead or a multiple level lead, e.g., a lead having a plurality of flat or paddle shaped lead bodies arranged in substantially parallel planes. Further, the lead may include fixation structures on the distal end, proximal end, or both ends to prevent migration.
摘要翻译： 本公开描述了用于将刺激递送给患者的可植入医疗引线。 电极可以位于引线的两个或更多个表面上，以例如选择性地将刺激递送到患者体内的一个或多个组织层。 铅可以植入在真皮内，深层皮肤或皮下组织层之内或之间，并且可以用于例如递送周围神经域刺激，以治疗患者在植入铅的部位所经历的疼痛 。 引线可以包括桨引线或多级引线，例如具有布置在基本上平行的平面中的多个扁平或桨状引线的引线。 此外，引线可以包括远端，近端或两端的固定结构，以防止迁移。
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公开(公告)号：US08108051B2
公开(公告)日：2012-01-31
申请号：US12710024
申请日：2010-02-22
申请人： Thomas E. Cross, Jr. , Gabor Racz
发明人： Thomas E. Cross, Jr. , Gabor Racz
IPC分类号： A61N1/00
CPC分类号： A61N1/0553 , Y10T29/49174
摘要： The present invention provides for an improved apparatus and method for electrical stimulation. A paddle having a thickness up to 0.030 inches is implanted adjacent the spinal cord dura mater to reduce the likelihood of paralysis due to stress on the spinal cord attributed to bulkier leads. The paddle is then positioned so that at least one of a plurality of electrodes is positioned over the area of the spinal cord requiring pain treatment; and then electric stimulation is applied to the electrodes to effect pain treatment. In another embodiment the paddle is curved about a vertical axis to substantially match the shape of a human spinal cord dura mater to help reduce lead migration.
摘要翻译： 本发明提供了用于电刺激的改进的装置和方法。 在脊髓硬脑膜附近植入具有高达0.030英寸厚度的桨叶，以减少由于大量引线引起的脊髓上的应力引起的麻痹的可能性。 然后将桨定位成使得多个电极中的至少一个位于需要疼痛治疗的脊髓区域上方; 然后对电极施加电刺激以进行疼痛治疗。 在另一个实施例中，桨叶围绕垂直轴线弯曲，以基本上匹配人脊髓硬脑膜的形状，以帮助减少铅迁移。
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