公开(公告)号：US20220138937A1

公开(公告)日：2022-05-05

申请号：US17429246

申请日：2020-02-06

Applicant: Konica Minolta, Inc.

Inventor： Etsuko FUTAYA ,  Hideki GODA

IPC: G06T7/00

Abstract: There is provided an information provision method for providing support information for supporting a judgement based on information obtained from a tissue section. The method includes: obtaining a digital bright-field image of a tissue section stained to be observable in a bright field; creating an analysis score by obtaining, combining, and scoring multiple kinds of information on the bright-field image; and presenting the analysis score as the support information.

公开(公告)号：US20180231466A1

公开(公告)日：2018-08-16

申请号：US15950648

申请日：2018-04-11

Applicant: Konica Minolta, Inc.

Inventor： Kensaku TAKANASHI ,  Hideki GODA ,  Hisatake OKADA ,  Yasushi NAKANO ,  Kohsuke GONDA ,  Motohiro TAKEDA ,  Noriaki OHUCHI

IPC: G01N21/64 ,  G01N33/483 ,  G01N33/58

CPC classification number: G01N21/6486 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/6489 ,  G01N33/4833 ,  G01N33/582 ,  G01N33/587 ,  G01N2021/6439

Abstract: A biological substance detection method for detecting a biological substance specifically in a pathological specimen, includes a step of immunologically staining the pathological specimen using a fluorescent label, a step of staining the pathological specimen with a staining reagent for morphology observation purposes (eosin) to observe the morphology of the pathological specimen, a step of irradiating the stained pathological specimen with excited light to cause the emission of a fluorescent and detecting the biological substance in the pathological specimen. In the step of immunologically staining the pathological specimen, a special fluorescent particle for which the excitation wavelength appears in a region that is different from the excitation wavelength region of eosin is used as the fluorescent label.

公开(公告)号：US20180209907A1

公开(公告)日：2018-07-26

申请号：US15745485

申请日：2016-07-15

Applicant: KONICA MINOLTA INC.

Inventor： Daisuke TOMIOKA ,  Hideki GODA ,  Akira SATO ,  Yuichi OZAKI ,  Masaru TAKAHASHI

IPC: G01N21/64 ,  G01N1/30 ,  G06K9/00

CPC classification number: G01N21/6458 ,  G01N1/30 ,  G01N21/64 ,  G01N33/533 ,  G01N33/6803 ,  G02B21/00 ,  G02B21/0076 ,  G06K9/0014 ,  G06T7/0012 ,  G06T2207/10024 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30242

Abstract: An analysis method of a target biological substance for analyzing a tissue specimen with a fluorescence microscope is provided. The tissue specimen is stained with immunostaining reagents including different kinds of fluorescent nanoparticles. According to the analysis method, a luminance ratio of each of the immunostaining reagents for each of filter sets is calculated; and number of fluorescent bright points is measured in the tissue specimen for each of the filter sets for calculating number of fluorescent bright points for each of the immunostaining reagents based on the luminance ratio.