公开(公告)号：US20230357711A1

公开(公告)日：2023-11-09

申请号：US18026474

申请日：2021-03-23

申请人： Konica Minolta, Inc.

发明人： TEMMEI ITO ,  AKIHIRO MAEZAWA ,  YASUHIKO TABATA ,  YUKI MURATA

IPC分类号： C12N5/00

CPC分类号： C12N5/0068 ,  C12N2533/30 ,  C12N2529/00 ,  C12N2533/54

摘要： The present invention relates to a cell support including a base material containing a biocompatible substance or a base material having a surface to which the biocompatible substance is imparted, and gelatin particles held by the biocompatible substance of the base material. The cell support can be produced by a method of causing the base material containing a biocompatible substance to hold the gelatin particles. By seeding cells on the cell support and culturing the cells, a cell structure in which a reagent or a drug has been uniformly taken into more cells can be obtained.

公开(公告)号：US20230340403A1

公开(公告)日：2023-10-26

申请号：US18026482

申请日：2020-09-17

申请人： Konica Minolta, Inc.

发明人： YASUHIKO TABATA ,  YUKI MURATA ,  TEMMEI ITO ,  AKIHIRO MAEZAWA

IPC分类号： C12N5/00

CPC分类号： C12N5/0068 ,  C12N2513/00 ,  C12N2533/54

摘要： The present invention relates to a cell-supporting body, including: a base material including a biocompatible substance; and a gelatin particle retained on the base material. The cell-supporting body can be manufactured by a method of retaining a gelatin particle on a base material including a biocompatible substance. By seeding a cell on the cell-supporting body and culturing the cell, a cell structure in which a reagent or an agent is uniformly incorporated into more cells can be obtained.

公开(公告)号：US20230088383A1

公开(公告)日：2023-03-23

申请号：US17910206

申请日：2020-03-12

申请人： Konica Minolta, Inc.

发明人： TEMMEI ITO ,  AKIHIRO MAEZAWA ,  YASUHIKO TABATA ,  YUKI MURATA

IPC分类号： C12Q1/6841 ,  C12Q1/6876

摘要： An object of the present invention is to provide a method for assessing a differentiation state of cells, capable of assessing a differentiation state of a wide variety of cells, and gelatin nanoparticles and a gelatin nanoparticle set that can be used in the method. The purpose is achieved by a method for assessing a differentiation state of cells, the method including a step of observing expression of an mRNA encoding a peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) or the peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) in cells. The method can be performed by gelatin nanoparticles for assessing a differentiation state of cells, the gelatin nanoparticles carrying a probe capable of detecting an mRNA encoding PGC-1α or PGC-1α