公开(公告)号：US11021586B2

公开(公告)日：2021-06-01

申请号：US15438215

申请日：2017-02-21

Applicant: Korea Institute of Science and Technology

Inventor： Nakwon Choi ,  Sohyun Kim ,  Sohyeon Jeong ,  Eui Sung Yoon ,  Changjoon Justin Lee ,  Il-Joo Cho

IPC: B29C43/18 ,  C08J7/043 ,  C08J7/04 ,  C12M3/00 ,  C12M1/12 ,  C12N5/00 ,  C12N5/09

Abstract: The present disclosure relates to an apparatus and a method for manufacturing a channel-coupled scaffold. The present disclosure provides a method for manufacturing a channel-coupled scaffold, which includes: (1) a step of compressing a first elastic substrate which includes a groove on the surface of the substrate to close the groove; (2) a step of loading a scaffold composition onto the closed groove; and (3) a step of restoring the elastic substrate. The present disclosure also provides an apparatus for manufacturing a channel-coupled scaffold, which includes: a first elastic substrate which includes a groove on the surface of the substrate and onto which a scaffold composition is loaded: and a compression module which compresses the width of the groove of the elastic substrate to close it. The apparatus or method may accumulate a microchannel controlling local mass transfer, and align a collagen fiber in the scaffold at the same time.