公开(公告)号：US20220282237A1

公开(公告)日：2022-09-08

申请号：US17637277

申请日：2020-08-25

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Ki Hyun NAM ,  Do Hyoung KIM ,  In Jeong KIM

IPC: C12N9/90 ,  C12P19/24

Abstract: The present invention relates to a novel fucose isomerase and a fucose production method using same. More specifically, in a reversible reaction between L-fucose and L-fuculose, an L-fucose isomerase, derived from a Raoultella sp. KDH 14 strain isolated from abalone intestines, favors the reaction progressing from L-fuculose to L-fucose, and thus the present invention provides the effect of applying same to the production of L-fucose.

公开(公告)号：US20220243188A1

公开(公告)日：2022-08-04

申请号：US17595616

申请日：2020-05-21

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Do Hyoung KIM

IPC: C12N9/24 ,  C12N15/63

Abstract: The present invention relates to use of an enzyme that cleaves both alpha- and beta-1,4-glycosidic bonds and, more particularly, the present invention provides α-L-fucosidase which has α-1,4-glucosidase and β-1,4-galactosidase activities and thus is capable of producing glucose and/or galactose, which are monosaccharides, from non-fucosylated saccharides. The enzyme has transglycosylation activity and thus produces maltooligosaccharides having a higher degree of polymerization than maltooligosaccharides used as a substrate, thereby being applicable to the development of high-value-added new materials in the food industry.

公开(公告)号：US20190309334A1

公开(公告)日：2019-10-10

申请号：US16315039

申请日：2017-06-30

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Damao WANG ,  Do Hyoung KIM

IPC: C12P19/02 ,  C12N9/24 ,  C12N15/52 ,  C12P19/14 ,  C12P19/12

Abstract: The present invention relates to a novel β-1,6-endoglucanase producing gentiobiose or glucose from β-glucan, and more specifically, the present invention provides an effect of producing gentiobiose or glucose at high yield through β-1,6-endoglucanase showing β-1,6-endoglucanase activity on β-glucan.

公开(公告)号：US20220033790A1

公开(公告)日：2022-02-03

申请号：US17299194

申请日：2019-12-04

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Thirumalaisamy BABU ,  Do Hyoung KIM ,  Jong Hwa LEE ,  Jung Moo LEE ,  Ho Chang LEE ,  Sung Ho OH ,  Su Han KIM ,  Chang Seok HYUN

IPC: C12N9/20 ,  C07K14/40 ,  C12P7/44

Abstract: The present invention relates to a Candida tropicalis cell line, which comprises a mutant gene, having improved tolerance for cytotoxicity of stromal cells, and a method for producing dicarboxylic acid using the Candida tropicalis cell line. The Candida tropicalis cell line for producing dicarboxylic acid developed according to the present invention has improved tolerance for existing stromal toxicity as well as significantly improved efficiency for producing dicarboxylic acid compared to existing cell lines, thus can be used in biological production of dicarboxylic acid and is expected to have high industrial utility.