公开(公告)号：US4774055A

公开(公告)日：1988-09-27

申请号：US877441

申请日：1986-06-23

申请人： Kouichi Wakatake ,  Takejirou Yokosuka ,  Hidehiko Fujioka ,  Teruo Mochida ,  Kazutomi Yokota

发明人： Kouichi Wakatake ,  Takejirou Yokosuka ,  Hidehiko Fujioka ,  Teruo Mochida ,  Kazutomi Yokota

IPC分类号： G01N21/25 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04

CPC分类号： G01N21/253 ,  G01N35/0095 ,  G01N35/025 ,  G01N2035/00435 ,  G01N2035/0097 ,  G01N2035/0448 ,  Y10S436/807

摘要： An automatic analysis apparatus is disclosed which provides for various analytical operations in clinical diagnosis and experiments including measuring the changes in light absorbance of a large number of samples mixed with different reagents in a progressive manner, biochemical, electrolytical, fluorescence, and immunological analysis and EIA analysis of samples in bead solid phase. A plurality of samples are maintained, together with diluents and emergency samples, in an ordered sequence on a sample table rotatably disposed which is rotated by drive means in a stepping manner to move the samples progressively to a predetermined suction position at which a sample pipetter picks up a measured amount of sample and dispenses it to one of a plurality of reaction containers that are arranged in an ordered sequence on a reaction table rotatably disposed, preferably about said sample table. A first and a second reagent table are provided, each carrying a plurality of reagents different in kind from one another, selected for various analyses to be performed. A first and a second reagent pipetter are provided and operated to pick up a measured amount of a particular reagent and mix it with any selected sample in the reaction containers. Each sample and reagent mixture may be scanned to measure the rate of light absorbance during a period of time as the reaction containers is rotated on the reaction table a photometer system including a rotating frame carrying thereon filters for different wavelengths through which the optical beam from a light source is passed to traverse the reaction container to be sensed by an optical sensor as the reaction container is rotated. Each reagent pipetting tube is provided with agitator means which is operated, after each dispensing operation of the pipetting tube into the reaction container, to stir the mixture in the reaction container into a homogenous state for proper reaction.

摘要翻译： 公开了一种自动分析装置，其提供临床诊断和实验中的各种分析操作，包括以逐步方式，生物化学，电解，荧光和免疫学分析和EIA测量与不同试剂混合的大量样品的吸光度变化 分析珠粒固相中的样品。 多个样品与稀释剂和紧急样品一起以有序的顺序保持在可旋转地布置的样品台上，该样品台由驱动装置以步进的方式旋转，以将样品逐渐移动到样品移液器拾取的预定抽吸位置 将测量量的样品分配到多个反应容器中的一个反应容器中，所述多个反应容器以有序的顺序排列在可旋转地设置的反应台上，优选地围绕所述样品台。 提供第一和第二试剂台，每个试剂台携带多个不同类型的试剂，选择用于进行各种分析。 提供并操作第一和第二试剂移液器以拾取测量量的特定试剂并将其与反应容器中的任何选定样品混合。 可以扫描每个样品和试剂混合物以测量一段时间内的光吸收率，因为反应容器在反应台上旋转，光度计系统包括带有不同波长的滤光片的旋转框架，光束仪来自 当反应容器旋转时，使光源穿过由光学传感器检测的反应容器。 每个试剂移液管设置有搅拌器装置，在每次将移液管分配到反应容器中之后，将反应容器中的混合物搅拌成均匀状态以进行适当的反应。