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21 条记录 (耗时 0.026 秒)

    Compositions of iodophenyl esters and iodophenyl sulfonates in film-forming materials for visualization of the gastrointestinal tract
    7.
    发明授权
    Compositions of iodophenyl esters and iodophenyl sulfonates in film-forming materials for visualization of the gastrointestinal tract 失效
    碘苯基酯和碘苯基磺酸盐在成膜材料中用于胃肠道可视化的组合物

    公开(公告)号：US5372800A

    公开(公告)日：1994-12-13

    申请号：US192234

    申请日：1994-02-04

    申请人： Edward R. Bacon ,  Sol J. Daum ,  Kimberly G. Estep ,  Kurt A. Josef ,  Brent D. Douty ,  Carl R. Illig

    发明人： Edward R. Bacon ,  Sol J. Daum ,  Kimberly G. Estep ,  Kurt A. Josef ,  Brent D. Douty ,  Carl R. Illig

    IPC分类号： A61K9/107 ,  A61K47/02 ,  A61K47/36 ,  A61K47/38 ,  A61K49/04 ,  C07C69/63

    CPC分类号： A61K49/0433 ,  Y10S514/941 ,  Y10S514/942

    摘要： Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1## and methods for their use in diagnostic radiology of the gastrointestinal tract whereinX= ##STR2## Z=H, halo, C.sub.1 -C.sub.20 alkyl, cycloalkyl, lower alkoxy, cyano, where the alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;R=C.sub.1 -C.sub.25 alkyl, cycloalkyl, aryl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, lower-alkoxy, hydroxy, carboxy or lower-alkoxy carbonyl, lower-alkenyl, lower-alkynyl, lower-alkylene or lower-alkoxy-carbonyloxy,n is 1-5;y is 0-4; andw is 1-4.

    摘要翻译： 公开了用于口腔或逆行检查胃肠道的x射线造影剂组合物，其包含能够在胃肠道上形成涂层的聚合物材料和具有式“IMAGE”的X射线产生剂及其用于诊断放射学的方法 的胃肠道，其中X = Z，H =卤素，C 1 -C 20烷基，环烷基，低级烷氧基，氰基，其中烷基和环烷基可被卤素或卤代低级烷基取代; R = C 1 -C 25烷基，环烷基，芳基或卤代低级烷基，任选被卤素，氟代低级烷基，低级烷氧基，羟基，羧基或低级烷氧基羰基，低级烯基，低级炔基，低级 - 亚烷基或低级 - 烷氧基 - 羰氧基，n为1-5; y为0-4; w为1-4。

    Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract
    8.
    发明授权
    Compositions of alkylbenzenes in film-forming materials for visualization of the gastrointestinal tract 失效
    用于胃肠道可视化的成膜材料中烷基苯的组成

    公开(公告)号：US5334370A

    公开(公告)日：1994-08-02

    申请号：US13459

    申请日：1993-02-04

    申请人： Kurt A. Josef ,  Edward R. Bacon ,  Kimberly G. Estep ,  Carl R. Illig ,  Brent D. Douty

    发明人： Kurt A. Josef ,  Edward R. Bacon ,  Kimberly G. Estep ,  Carl R. Illig ,  Brent D. Douty

    IPC分类号： A61K49/04 ,  C07C17/12 ,  C07C17/26 ,  C07C17/354 ,  C07C25/02 ,  C07C69/65 ,  C07C22/00 ,  C07C25/00 ,  C07C69/76

    CPC分类号： C07C17/12 ,  A61K49/0461 ,  C07C17/2635 ,  C07C17/354 ,  C07C25/02 ,  C07C69/65

    摘要： Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula ##STR1## and methods for their use in diagnostic radiology of the gastrointestinal tract whereinR=C.sub.1 -C.sub.25 alkyl, cycloalkyl, unsaturated allyl or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl, aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxy-carbonyloxy, (CR.sub.1 R.sub.2).sub.p --(CR.sub.3 .dbd.CR.sub.4).sub.m Q, or (CR.sub.1 R.sub.2).sub.p --C.tbd.C--Q;R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently H, lower-alkyl, optionally substituted with halo;n is 1-5;m is 1-5;p is 1-10; andQ is H, lower-alkyl, lower-alkenyl, lower-alkynyl, lower-alkylene, aryl, or aryl-lower alkyl.

    摘要翻译： 公开了用于口腔或逆行检查胃肠道的x射线造影剂组合物，其包含能够在胃肠道上形成涂层的聚合物材料和具有式“IMAGE”的X射线产生剂及其用于诊断放射学的方法 的胃肠道，其中R = C 1 -C 25烷基，环烷基，不饱和烯丙基或卤代低级烷基，任选被卤素，氟 - 低级 - 烷基，芳基，低级 - 烷氧基，羟基，羧基，低级 - 烷氧基羰基或低级 （CR 1 R 2）p - （CR 3 = CR 4）m Q或（CR 1 R 2）p C 3 B 3 CQ; R 1，R 2，R 3和R 4独立地为H，低级烷基，任选被卤素取代; n为1-5; m为1-5; p为1-10; 并且Q是H，低级烷基，低级烯基，低级炔基，低级亚烷基，芳基或芳基 - 低级烷基。