公开(公告)号：US20100181209A1

公开(公告)日：2010-07-22

申请号：US12637245

申请日：2009-12-14

申请人： Kyu-tae YOO ,  Sung-ouk JUNG ,  Jun-hong MIN ,  Ji-na NAMGOONG ,  Soo-hyung CHOI ,  Jeo-young SHIM

发明人： Kyu-tae YOO ,  Sung-ouk JUNG ,  Jun-hong MIN ,  Ji-na NAMGOONG ,  Soo-hyung CHOI ,  Jeo-young SHIM

IPC分类号： G01N27/26

CPC分类号： G01N33/54306

摘要： Provided is a method of sensing biomolecules using a bioFET, the method including: forming a layer including Au on a gate of the bioFET; forming a probe immobilized on a substrate separated from the gate by a predetermined distance, and a biomolecule having a thiol group (—SH) which is incompletely bonded to the probe; reacting the probe with a sample including a target molecule; and measuring a current flowing in a channel region between a source and a drain of the bioFET.

摘要翻译： 提供了一种使用bioFET感测生物分子的方法，该方法包括：在bioFET的栅极上形成包含Au的层; 形成固定在与栅极分离预定距离的基板上的探针，以及具有与探针不完全结合的硫醇基（-SH）的生物分子; 使探针与包含靶分子的样品反应; 以及测量在bioFET的源极和漏极之间的沟道区域中流动的电流。

公开(公告)号：US20080135101A1

公开(公告)日：2008-06-12

申请号：US11869835

申请日：2007-10-10

申请人： Hun-joo LEE ,  Nam HUH ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Soo-hyung CHOI

发明人： Hun-joo LEE ,  Nam HUH ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Soo-hyung CHOI

IPC分类号： B81B1/00 ,  B21D51/16 ,  G05D7/03

CPC分类号： G05D7/0694 ,  Y10T29/494 ,  Y10T137/0753 ,  Y10T137/2191 ,  Y10T137/86187

摘要： The microfluidic device includes a rotatable platform, a plurality of connection ports disposed at a portion of the platform proximate to a shaft connection hole, the plurality of connection ports capable of being connected to an external connector for selectively injecting and discharging fluid and being closed by the connector, a trap chamber disposed at a portion of the platform further away from the shaft connection hole than the plurality of connection ports, the trap chamber including an inlet connected with at least one connection port of the plurality of connection ports, an outlet connected with another connection port of the plurality of connection ports and structures which enlarge a contact area with the fluid and a temporary storage including an inlet connected with the outlet of the trap chamber and an outlet connected with another connection port of the plurality of connection ports.

摘要翻译： 所述微流体装置包括可旋转平台，多个连接端口，设置在所述平台的靠近轴连接孔的部分处，所述多个连接端口能够连接到外部连接器，用于选择性地注入和排出流体并且由 所述连接器，设置在所述平台的远离所述轴连接孔的所述平台部分处的所述收集室，所述收集室包括与所述多个连接端口中的至少一个连接端口连接的入口，所述入口连接到所述入口 多个连接端口中的另一个连接端口和扩大与流体的接触面积的结构以及包括与捕集室的出口连接的入口的临时存储器和与多个连接端口中的另一连接端口连接的出口。

公开(公告)号：US20110256570A1

公开(公告)日：2011-10-20

申请号：US13155944

申请日：2011-06-08

申请人： Jung-im HAN ,  Soo-hyung CHOI ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Joon-shik PARK ,  Ki-eun KIM

发明人： Jung-im HAN ,  Soo-hyung CHOI ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Joon-shik PARK ,  Ki-eun KIM

IPC分类号： C12Q1/32 ,  C12Q1/00

CPC分类号： G01N33/5079 ,  G01N2333/90209

摘要： A method of positively detecting toxic materials within a sample, the method including contacting sub-mitochondrial particles having competent mitochondrial enzymes formed from inner membranes of mitochondria, an electron donor which transmits electrons to an electron transfer system of the sub-mitochondrial particles and the sample, and forming reaction resultants, adjusting a pH of a pH indicator which change color according to a change in pH, adding the pH indicators to each reaction resultant and identifying color changes of the pH indicator. Also provided is a kit for positively detecting toxic materials within a sample.

摘要翻译： 一种积极检测样品内的有毒物质的方法，该方法包括使具有由线粒体内膜形成的感受态线粒体酶的亚线粒体颗粒，将电子传递到亚线粒体颗粒的电子转移系统的电子给体和样品 ，并形成反应产物，调节pH指示剂的pH值，根据pH的变化改变颜色，向每个反应产物添加pH指示剂并鉴定pH指示剂的颜色变化。 还提供了用于积极检测样品中有毒物质的试剂盒。

公开(公告)号：US20080142361A1

公开(公告)日：2008-06-19

申请号：US11745522

申请日：2007-05-08

申请人： Jung-im HAN ,  Soo-hyung CHOI ,  Jeong-hee LEE ,  Soo-suk LEE ,  Jeong-na HEO

发明人： Jung-im HAN ,  Soo-hyung CHOI ,  Jeong-hee LEE ,  Soo-suk LEE ,  Jeong-na HEO

IPC分类号： G01N27/26 ,  B05D3/00 ,  B05D5/00

CPC分类号： G01N27/127 ,  Y10S977/742 ,  Y10S977/743 ,  Y10S977/953 ,  Y10S977/957

摘要： A carbon nanotube (“CNT”) gas sensor includes a substrate, an insulating layer formed on the substrate, electrodes formed on the insulating layer, and CNT barriers that protrude higher than the electrodes in spaces between the electrodes to form gas detecting spaces. A method of manufacturing the gas sensor includes forming an insulating layer on a substrate, forming an electrode pattern on the insulating layer, coating CNT paste having a thickness greater than a thickness of electrodes in the electrode pattern on the electrodes and the insulating layer, and patterning and firing the carbon nanotube paste, including using a photolithography method, to retain only portions of the CNT paste coated on spaces between the electrodes.

摘要翻译： 碳纳米管（“CNT”）气体传感器包括基板，形成在基板上的绝缘层，形成在绝缘层上的电极和在电极之间的空间中比电极突出的CNT势垒，以形成气体检测空间。 制造气体传感器的方法包括在基板上形成绝缘层，在绝缘层上形成电极图案，在电极和绝缘层上涂覆厚度大于电极图案的电极厚度的CNT浆料，以及 包括使用光刻法构图和烧制碳纳米管糊，仅保留涂覆在电极之间的间隙上的部分CNT浆料。

公开(公告)号：US20070148723A1

公开(公告)日：2007-06-28

申请号：US11610851

申请日：2006-12-14

申请人： Jung-im HAN ,  Soo-hyung CHOI

发明人： Jung-im HAN ,  Soo-hyung CHOI

IPC分类号： C12Q1/26

CPC分类号： G01N33/5079 ,  G01N33/5035 ,  G01N2333/90209

摘要： Provided is a method for detecting the degree of toxicity of toxic materials within a sample. The method includes contacting sub-mitochondrial particles having competent mitochondrial enzyme formed from the inner membranes of mitochondria, an electron donor which transmits electrons to the electron transfer system of the sub-mitochondrial particles, and a sample which will be tested; adding tris-2,2′-bipyridyl-ruthenium (II) ion to the reaction mixture; and measuring electrical variables of the reaction mixture. Also, provided is an apparatus and kit for detecting the presence of toxic materials within a sample.

摘要翻译： 提供了用于检测样品中有毒物质的毒性程度的方法。 该方法包括使具有由线粒体内膜形成的具有感受态的线粒体酶的亚线粒体颗粒和将电子传递到亚线粒体颗粒的电子传递系统的电子供体以及待测试的样品; 向反应混合物中加入三 - 2,2'-联吡啶 - 钌（II）离子; 并测量反应混合物的电变量。 此外，提供了用于检测样品中有毒物质的存在的装置和试剂盒。