公开(公告)号：US08257241B2

公开(公告)日：2012-09-04

申请号：US12557040

申请日：2009-09-10

申请人： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

发明人： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

IPC分类号： A61M36/12

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： A brachytherapy device for treating tissue within a cavity of a body. The device may include a first set of tubes configured to be inserted into the cavity through an opening at the surface of the body. Each of the tubes may have an external end and an interior channel beginning at the external end that is configured to receive radioactive material. The external ends of the tubes may be bundled together. The tubes may be of a length that causes the external ends to be near the opening in the surface of the body while the tubes are in the cavity. A seal may be configured to prevent fluid that originates from the cavity from entering into the external ends of the tubes while they are near the opening in the surface of the body. The seal may include a gasket that is pressed against the external ends of the tubes. The gasket may have openings that align with channels within the external ends of the tubes.

摘要翻译： 一种用于治疗身体空腔内的组织的近距离放射治疗装置。 该装置可以包括构造成通过身体表面处的开口插入空腔中的第一组管。 每个管可以具有外部端和从外部端开始的内部通道，其构造成接收放射性材料。 管的外端可以捆扎在一起。 管可以具有这样的长度，即当管在空腔中时，外端在壳体表面的开口附近。 密封件可以构造成防止来自腔的流体在它们靠近体表面的开口处时进入管的外端。 密封件可以包括被压靠在管的外端的垫圈。 垫圈可以具有与管的外端内的通道对准的开口。

公开(公告)号：US20100204536A1

公开(公告)日：2010-08-12

申请号：US12557040

申请日：2009-09-10

申请人： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

发明人： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

IPC分类号： A61M36/12

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： A brachytherapy device for treating tissue within a cavity of a body. The device may include a first set of tubes configured to be inserted into the cavity through an opening at the surface of the body. Each of the tubes may have an external end and an interior channel beginning at the external end that is configured to receive radioactive material. The external ends of the tubes may be bundled together. The tubes may be of a length that causes the external ends to be near the opening in the surface of the body while the tubes are in the cavity. A seal may be configured to prevent fluid that originates from the cavity from entering into the external ends of the tubes while they are near the opening in the surface of the body. The seal may include a gasket that is pressed against the external ends of the tubes. The gasket may have openings that align with channels within the external ends of the tubes.

摘要翻译： 一种用于治疗身体空腔内的组织的近距离放射治疗装置。 该装置可以包括构造成通过身体表面处的开口插入空腔中的第一组管。 每个管可以具有外部端和从外部端开始的内部通道，其构造成接收放射性材料。 管的外端可以捆扎在一起。 管可以具有这样的长度，即当管在空腔中时，外端在壳体表面的开口附近。 密封件可以构造成防止来自腔的流体在它们靠近体表面的开口处时进入管的外端。 密封件可以包括被压靠在管的外端的垫圈。 垫圈可以具有与管的外端内的通道对准的开口。

公开(公告)号：US20080269539A1

公开(公告)日：2008-10-30

申请号：US11741670

申请日：2007-04-27

申请人： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

发明人： L. Michael Cutrer ,  Leigh Spotten ,  Joseph Wong ,  Fredrick Winch

IPC分类号： A61M36/12

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： A brachytherapy device for treating tissue within a cavity of a body. The device may include a first set of tubes configured to be inserted into the cavity through an opening at the surface of the body. Each of the tubes may have an external end and an interior channel beginning at the external end that is configured to receive radioactive material. The external ends of the tubes may be bundled together. The tubes may be of a length that causes the external ends to be near the opening in the surface of the body while the tubes are in the cavity. A seal may be configured to prevent fluid that originates from the cavity from entering into the external ends of the tubes while they are near the opening in the surface of the body. The seal may include a gasket that is pressed against the external ends of the tubes. The gasket may have openings that align with channels within the external ends of the tubes.

摘要翻译： 一种用于治疗身体空腔内的组织的近距离放射治疗装置。 该装置可以包括构造成通过身体表面处的开口插入空腔中的第一组管。 每个管可以具有外部端和从外部端开始的内部通道，其构造成接收放射性材料。 管的外端可以捆扎在一起。 管可以具有这样的长度，即当管在空腔中时，外端在壳体表面的开口附近。 密封件可以构造成防止来自腔的流体在它们靠近体表面的开口处时进入管的外端。 密封件可以包括被压靠在管的外端的垫圈。 垫圈可以具有与管的外端内的通道对准的开口。

公开(公告)号：US20080108859A1

公开(公告)日：2008-05-08

申请号：US11737028

申请日：2007-04-18

申请人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Joe Wong ,  Fredrick Winch

发明人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Joe Wong ,  Fredrick Winch

IPC分类号： A61M36/12

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： A brachytherapy device may include an expandable outer cage, an expandable inner cage positioned within the outer cage and configured to receive radioactive material at its perimeter, and a movable actuator configured to cause the outer and inner cages to expand simultaneously in response to movement of the actuator between certain positions while maintaining a substantially constant separation distance between the outer and inner cages.

摘要翻译： 近距离放射治疗装置可以包括可扩张的外笼，位于外笼内并被配置为在其外周处接收放射性物质的可扩展的内笼，以及可移动的致动器，该致动器构造成使得外壳和内笼同时响应于 致动器在某些位置之间，同时保持外笼和内笼之间的基本恒定的间隔距离。

公开(公告)号：US08137256B2

公开(公告)日：2012-03-20

申请号：US11305437

申请日：2005-12-16

申请人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Fredrick Winch ,  John Zhang ,  Wayne Higgins ,  Terence Ellard ,  David Bossi

发明人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Fredrick Winch ,  John Zhang ,  Wayne Higgins ,  Terence Ellard ,  David Bossi

IPC分类号： A61N5/00

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： The present disclosure provides a brachytherapy apparatus that delivers a low dose, partial breast irradiation treatment for post-lumpectomy patients via introduction of a catheter-like device through a cannula. The apparatus may be introduced post-surgically with local anesthesia under image guidance into the previous excision site and into a cavity by a surgeon. The brachytherapy apparatus includes a seed containment device configured to contain a plurality of low-dose radioactive seeds therein. The seed containment device may be one or more thin-walled tubes. The apparatus is further configured to expand so that at least a portion of the seed containment device is positioned against the remaining tissue and the plurality of radioactive seeds are disposed at the perimeter of the seed containment device. Also described are various clamps for the apparatus, and sleeves for adjusting the size of the device to fit a cavity when the apparatus is in use.

摘要翻译： 本公开提供了一种近距离放射治疗装置，其通过经由插管引入导管状装置来递送针对后肿瘤切除术患者的低剂量部分乳房照射治疗。 该装置可以在图像引导下用手术后的局部麻醉引入先前的切除部位并由外科医生进入腔中。 近程放射治疗装置包括种子容纳装置，其构造成在其中容纳多个低剂量放射性种子。 种子容纳装置可以是一个或多个薄壁管。 该装置进一步构造成扩张，使得种子容纳装置的至少一部分抵靠剩余的组织定位，并且多个放射性种子设置在种子容纳装置的周边。 还描述了用于装置的各种夹具以及用于在装置使用时调节装置的尺寸以配合空腔的套筒。

公开(公告)号：US20070142694A1

公开(公告)日：2007-06-21

申请号：US11305437

申请日：2005-12-16

申请人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Fredrick Winch ,  John Zhang ,  Wayne Higgins ,  Terence Ellard ,  David Bossi

发明人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Fredrick Winch ,  John Zhang ,  Wayne Higgins ,  Terence Ellard ,  David Bossi

IPC分类号： A61N5/00 ,  A61M36/00

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： The present disclosure provides a brachytherapy apparatus that delivers a low dose, partial breast irradiation treatment for post-lumpectomy patients via introduction of a catheter-like device through a cannula. The apparatus may be introduced post-surgically with local anesthesia under image guidance into the previous excision site and into a cavity by a surgeon. The brachytherapy apparatus includes a seed containment device configured to contain a plurality of low-dose radioactive seeds therein. The seed containment device may be one or more thin-walled tubes. The apparatus is further configured to expand so that at least a portion of the seed containment device is positioned against the remaining tissue and the plurality of radioactive seeds are disposed at the perimeter of the seed containment device. Also described are various clamps for the apparatus, and sleeves for adjusting the size of the device to fit a cavity when the apparatus is in use.

摘要翻译： 本公开提供了一种近距离放射治疗装置，其通过经由插管引入导管状装置来递送针对后肿瘤切除术患者的低剂量部分乳房照射治疗。 该装置可以在图像引导下用手术后的局部麻醉引入先前的切除部位并由外科医生进入腔中。 近程放射治疗装置包括种子容纳装置，其构造成在其中容纳多个低剂量放射性种子。 种子容纳装置可以是一个或多个薄壁管。 该装置进一步构造成扩张，使得种子容纳装置的至少一部分抵靠剩余的组织定位，并且多个放射性种子设置在种子容纳装置的周边。 还描述了用于装置的各种夹具以及用于在装置使用时调节装置的尺寸以配合空腔的套筒。

公开(公告)号：US20100191034A1

公开(公告)日：2010-07-29

申请号：US12544101

申请日：2009-08-19

申请人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Joe Wong ,  Fredrick Winch

发明人： L. Michael Cutrer ,  Richard A. Terwilliger ,  Joe Wong ,  Fredrick Winch

IPC分类号： A61M36/04

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： A brachytherapy device may include an expandable outer cage, an expandable inner cage positioned within the outer cage and configured to receive radioactive material at its perimeter, and a movable actuator configured to cause the outer and inner cages to expand simultaneously in response to movement of the actuator between certain positions while maintaining a substantially constant separation distance between the outer and inner cages.

摘要翻译： 近距离放射治疗装置可以包括可扩张的外笼，位于外笼内并被配置为在其外周处接收放射性物质的可扩展的内笼，以及可移动的致动器，该致动器构造成使得外壳和内笼同时响应于 致动器在某些位置之间，同时保持外笼和内笼之间的基本恒定的间隔距离。

公开(公告)号：US07357770B1

公开(公告)日：2008-04-15

申请号：US11737028

申请日：2007-04-18

申请人： L. Michael Cutrer ,  Richard A Terwilliger ,  Joe Wong ,  Fredrick Winch

发明人： L. Michael Cutrer ,  Richard A Terwilliger ,  Joe Wong ,  Fredrick Winch

IPC分类号： A61N5/00

CPC分类号： A61N5/1015 ,  A61N2005/1018

摘要： A brachytherapy device may include an expandable outer cage, an expandable inner cage positioned within the outer cage and configured to receive radioactive material at its perimeter, and a movable actuator configured to cause the outer and inner cages to expand simultaneously in response to movement of the actuator between certain positions while maintaining a substantially constant separation distance between the outer and inner cages.

摘要翻译： 近距离放射治疗装置可以包括可扩张的外笼，位于外笼内并被配置为在其外周处接收放射性物质的可扩展的内笼，以及可移动的致动器，该致动器构造成使得外壳和内笼同时响应于 致动器在某些位置之间，同时保持外笼和内笼之间的基本恒定的间隔距离。