公开(公告)号：US20140273083A1

公开(公告)日：2014-09-18

申请号：US14204580

申请日：2014-03-11

Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBH

Inventor： Stella KNORR ,  Andrew GUY ,  Ralf ECKERT ,  Fiona TARBET ,  Fernando DIAS ,  Chris RYAN ,  Neil SANUT

IPC: G01N1/36

CPC classification number: G01N1/36 ,  B01L3/502 ,  B01L3/50855 ,  B01L2300/0609

Abstract: A method for treating a tissue sample including placing at least one tissue sample on an cassette which has: a retaining member, a base and at least one biasing element; placing the at least one tissue sample in the tissue cassette; attaching the base and the retaining member to retain the tissue sample; processing the tissue sample in the tissue cassette with one or more solvents; and embedding the tissue sample in a paraffin to form an portion of paraffin in which the tissue sample is embedded in the tissue cassette, wherein the embedding comprises adding molten paraffin to the interior area of the tissue cassette and allowing the paraffin to become solid.

Abstract translation: 一种用于处理组织样本的方法，包括将至少一个组织样本放置在具有保持构件，基底和至少一个偏压元件的盒上。 将所述至少一个组织样本放置在所述组织盒中; 附接基部和保持构件以保持组织样本; 用一种或多种溶剂处理组织盒中的组织样品; 以及将所述组织样品包埋在石蜡中以形成其中所述组织样本被包埋在所述组织盒中的石蜡的一部分，其中所述包埋包括将熔融石蜡加入到所述组织盒的内部区域中，并允许所述石蜡变成固体。

公开(公告)号：US20160216176A1

公开(公告)日：2016-07-28

申请号：US15091653

申请日：2016-04-06

Applicant: Leica Biosystems Nussloch GmbH

Inventor： Stella KNORR ,  Andrew GUY ,  Ralf ECKERT ,  Fiona TARBET ,  Fernando DIAS ,  Chris RYAN ,  Neil SANUT

IPC: G01N1/31 ,  B01L3/00

CPC classification number: G01N1/31 ,  B01L3/508 ,  B01L3/5457 ,  B01L2200/14 ,  B01L2300/021 ,  B01L2300/043 ,  B01L2300/0609 ,  B01L2300/12 ,  B01L2300/123 ,  G01N1/36 ,  G01N2001/315 ,  G01N2001/366

Abstract: An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.

Abstract translation: 一种用于保持组织样本的装置，包括具有第一组织接合表面和至少一个偏置元件的保持构件，所述第一组织接合表面通过所述偏置元件可移动地附接到所述保持构件; 以及具有第二组织接合表面并且构造成与所述保持构件接合以形成所述第一和第二组织接合表面彼此面对的内部区域的底座，其中所述至少一个偏置元件将所述第一组织接合表面推向所述第二组织 接合表面以将组织样本保持在内部区域中。

公开(公告)号：US20140273084A1

公开(公告)日：2014-09-18

申请号：US14204587

申请日：2014-03-11

Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBH

Inventor： Florian BOEHL ,  Stella KNORR ,  Peter KOTLARSKI ,  Graeme ROBERTSON ,  Chris RYAN ,  Ian SOHN ,  Wilfred BAUWENS ,  Fernando DIAS

IPC: G01N1/31

CPC classification number: G01N1/31 ,  B01L3/508 ,  B01L2300/0609 ,  G01N1/36 ,  G01N2001/315 ,  G01N2001/366

Abstract: An apparatus for holding a tissue sample having a retaining member with a first tissue engaging surface and at least one biasing element. The first tissue engaging surface is moveably attached to the retaining member. The apparatus also has a base comprising a second tissue engaging surface which is configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other. The apparatus also has a retracting member connected to the retaining member which is configured to retract the first tissue engaging surface and compress the biasing element to form a gap between the tissue sample and one of the first tissue engaging surface and the second tissue engaging surface.

Abstract translation: 一种用于保持具有第一组织接合表面的保持构件的组织样本和至少一个偏置元件的装置。 第一组织接合表面可移动地附接到保持构件。 该装置还具有包括第二组织接合表面的底座，该第二组织接合表面构造成与保持构件接合以形成第一和第二组织接合表面彼此面对的内部区域。 该装置还具有连接到保持构件的缩回构件，该缩回构件被构造成缩回第一组织接合表面并且压缩偏置元件以在组织样本与第一组织接合表面和第二组织接合表面中的一个之间形成间隙。

公开(公告)号：US20140271407A1

公开(公告)日：2014-09-18

申请号：US14204375

申请日：2014-03-11

Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBH

Inventor： Stella KNORR ,  Andrew GUY ,  Ralf ECKERT ,  Fiona TARBET ,  Fernando DIAS ,  Chris RYAN ,  Neil SANUT

IPC: G01N1/31

CPC classification number: G01N1/31 ,  B01L3/508 ,  B01L3/5457 ,  B01L2200/14 ,  B01L2300/021 ,  B01L2300/043 ,  B01L2300/0609 ,  B01L2300/12 ,  B01L2300/123 ,  G01N1/36 ,  G01N2001/315 ,  G01N2001/366

Abstract: An apparatus for holding a tissue sample including a retaining member having a first tissue engaging surface and at least one biasing element, the first tissue engaging surface being moveably attached to the retaining member by said biasing element; and a base having a second tissue engaging surface and configured to engage the retaining member to form an interior area with the first and second tissue engaging surfaces facing each other, wherein the at least one biasing element urges the first tissue engaging surface toward the second tissue engaging surface to retain the tissue sample therebetween in the interior area.

Abstract translation: 一种用于保持组织样本的装置，包括具有第一组织接合表面和至少一个偏置元件的保持构件，所述第一组织接合表面通过所述偏置元件可移动地附接到所述保持构件; 以及具有第二组织接合表面并且构造成与所述保持构件接合以形成所述第一和第二组织接合表面彼此面对的内部区域的底座，其中所述至少一个偏压元件将所述第一组织接合表面推向所述第二组织 接合表面以将组织样本保持在内部区域中。