公开(公告)号：US20190250174A1

公开(公告)日：2019-08-15

申请号：US16276077

申请日：2019-02-14

申请人： SAMSUNG ELECTRONICS CO., LTD.

发明人： Eun Jeong JANG ,  Ki Ju LEE

IPC分类号： G01N33/80 ,  G01N35/00 ,  G01N33/50 ,  B01L3/00 ,  B01L9/00

CPC分类号： G01N33/80 ,  B01L3/508 ,  B01L9/52 ,  B01L2200/143 ,  B01L2300/025 ,  G01N33/5005 ,  G01N35/00732 ,  G01N2035/00752 ,  G01N2035/00772 ,  G01N2035/00831

摘要： A blood testing apparatus includes an analyzer configured to analyze blood components of an animal that are included in a test medium; an output device configured to display analysis results of the blood components; and a controller configured to determine a species of the animal based on at least one from among types of the blood components and the analysis results of the blood components and control the output device to display the determined species of the animal.

公开(公告)号：US20190249171A1

公开(公告)日：2019-08-15

申请号：US16272870

申请日：2019-02-11

申请人： Illumina, Inc.

发明人： Yir-Shyuan Wu ,  Filiz Gorpe-Yasar ,  Tarun Kumar Khurana ,  Victoria Popic ,  Erich B. Jaeger ,  Mostafa Ronaghi

IPC分类号： C12N15/10 ,  C12Q1/6806 ,  B01L3/00 ,  B01L7/00

CPC分类号： C12N15/1068 ,  B01L3/508 ,  B01L7/52 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/123 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q2523/101 ,  C12Q2527/156 ,  C12Q2531/119 ,  C12Q2535/122 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q2565/629

摘要： Systems, methods, and compositions provided herein relate to preparation of beads encapsulating long DNA fragments for high-throughput spatial indexing. Some embodiments include preparation of nucleic acid libraries within the bead, wherein the bead includes pores that allow diffusion of reagents while retaining genetic material.

公开(公告)号：US20190201907A1

公开(公告)日：2019-07-04

申请号：US16215837

申请日：2018-12-11

申请人： Thermo Electron Scientific Instruments LLC

发明人： Nathaniel S. Safron ,  Matthew Wayne Meyer ,  John Magie Coffin

IPC分类号： B01L9/00 ,  B01L3/00

CPC分类号： B01L9/52 ,  B01F11/0022 ,  B01F11/0034 ,  B01F2215/0037 ,  B01L3/508 ,  B01L2300/0609 ,  B01L2300/0663 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/123 ,  B01L2400/043 ,  B01L2400/0433

摘要： A mixing apparatus includes a well plate assembly including a fixed support, and a well movable with respect to the fixed support. A fixed sensor mount has a first portion disposed above the well and a second portion disposed within the well. A plurality of electromagnets are operable to move the well plate assembly vertically with respect to the fixed sensor mount and the fixed support.

公开(公告)号：US20190201899A1

公开(公告)日：2019-07-04

申请号：US16226590

申请日：2018-12-19

申请人： STMICROELECTRONICS S.R.L.

发明人： Marco CEREDA ,  Lillo RAIA ,  Alessandro Paolo BRAMANTI

IPC分类号： B01L3/00 ,  C12N15/10

CPC分类号： B01L9/527 ,  B01L3/5023 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/5029 ,  B01L3/508 ,  B01L3/5082 ,  B01L3/50825 ,  B01L3/52 ,  B01L3/523 ,  B01L3/527 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0621 ,  B01L2200/0642 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/022 ,  B01L2300/023 ,  B01L2300/044 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/08 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/16 ,  B01L2300/1827 ,  B01L2400/04 ,  B01L2400/0406 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/049 ,  B01L2400/0677 ,  B29C43/021 ,  B29C43/14 ,  B29C43/18 ,  B29L2031/753

摘要： A solid reagent containment unit is formed by a support; a frame body fixed to the support and delimiting internally, together with the support, an analysis volume; a reagent-adhesion structure within the analysis volume; and at least one reagent cavity, which extends within the reagent-adhesion structure. The reagent-adhesion structure is of an adhesion material embossable at temperatures lower by 6-8° C. than its own melting point and has a melting point such as not to interfere with the analysis. The reagent cavity forms a retention wall, laterally surrounding the reagent cavity, and houses dried reagents. The adhesion material is chosen among wax, such as paraffin, a polymer, such as polycaprolactone, a solid fat, such as cocoa butter, and a gel, such as hydrogel or organogel.

公开(公告)号：US20190195752A1

公开(公告)日：2019-06-27

申请号：US16291542

申请日：2019-03-04

申请人： Lee H. Angros

发明人： Lee H. Angros

IPC分类号： G01N1/30 ,  B05D1/02 ,  B05D1/20 ,  B01L3/00 ,  B01L99/00 ,  B05C1/02 ,  B05C13/02 ,  B05D1/28 ,  B05D7/00 ,  B05C11/02

CPC分类号： G01N1/30 ,  B01L3/0258 ,  B01L3/508 ,  B01L99/00 ,  B01L2200/12 ,  B01L2300/0822 ,  B01L2300/16 ,  B01L2300/161 ,  B05C1/025 ,  B05C9/06 ,  B05C9/14 ,  B05C11/028 ,  B05C13/02 ,  B05D1/02 ,  B05D1/20 ,  B05D1/28 ,  B05D7/5483 ,  B05D2252/04 ,  G01N2001/305 ,  Y10T156/179 ,  Y10T156/1798

摘要： An apparatus and method for producing a coated analytic substrate using a compact and portable automated instrument located in the laboratory setting at the point of use which can consistently produce one or a plurality of coated analytic substrates “on demand” for using the analytic substrate immediately after coating, preferably without a step of rinsing the coated analytic substrate before use. The apparatus preferably uses applicator cartridges having a reservoir containing the coating compositions used to form the coatings. Preferably the cartridges are removable and interchangeable to facilitate the production of individual analytic substrates having different coatings or different coating patterns. These coated analytic substrates have superior specimen adhesion characteristics due to the improved quality of the coatings applied by the coating apparatus and due to the quickness with which the coated analytic substrates can be used in the lab after production.

公开(公告)号：US20180340838A1

公开(公告)日：2018-11-29

申请号：US15987869

申请日：2018-05-23

申请人： Barry Nicholson, JR.

发明人： Barry Nicholson, JR.

IPC分类号： G01K1/02 ,  G01K3/10 ,  B01L3/00 ,  G06K19/077

CPC分类号： G01K1/024 ,  B01L3/508 ,  B01L3/54 ,  B01L3/545 ,  B01L9/52 ,  B01L2200/147 ,  B01L2300/021 ,  B01L2300/022 ,  B01L2300/025 ,  B01L2300/0627 ,  G01K1/143 ,  G01K3/10 ,  G01K7/223 ,  G02B21/34 ,  G06K19/07758

摘要： This disclosure describes a slide comprising a substrate, a RFID or WISP, and a temperature sensor, wherein the slide is capable of communicating with an external communications device via the RFID or WISP. In some implementations, the RFID or WISP of the slide comprises an antenna, an integrated circuit, a memory unit, and a power source, such that it is capable of measuring and logging data related to time and temperature. In some implementations, the RFID or WISP and temperature sensor are embedded in the substrate to prevent direct contact with mounted specimens. In some implementations the slide further comprises displayed content. In some implementations, the displayed content is linked to a database of information. The various implementations of this invention may describe a slide utilizing any number of the features described above in any combination.

公开(公告)号：US20180243743A1

公开(公告)日：2018-08-30

申请号：US15756176

申请日：2015-09-02

申请人： Thoms PERROUD ,  Dan TRAN ,  Daniel HOFFMEYER ,  Tiffany LAY ,  Manjeet DHINDSA ,  TECAN TRADING AG

发明人： THOMAS PERROUD ,  Dan TRAN ,  Daniel HOFFMEYER ,  Tiffany LAY ,  Manjeet DHINDSA

IPC分类号： B01L3/00

CPC分类号： C02F1/484 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502761 ,  B01L3/502792 ,  B01L3/508 ,  B01L2200/025 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/123 ,  B01L2400/0427 ,  B01L2400/043

摘要： A digital microfluidics system with electrodes attached to a substrate and covered by a hydrophobic surface, and a control unit for manipulating liquid droplets by electrowetting; providing in close proximity to electrodes a magnetic conduit for directing a magnetic field of a backing magnet to the first hydrophobic surface; providing on the hydrophobic surface a liquid droplet that has magnetically responsive beads; moving by electrowetting the liquid droplet with the magnetically responsive beads until a part of which is placed atop of the magnetic conduit; actuating the backing magnet of the magnetic conduit and attracting/concentrating magnetically responsive beads; and while actuating the backing magnet, moving by electrowetting the liquid droplet with decreased number of magnetically responsive beads away from the specific magnetic conduit. Also disclosed are a method for suspending magnetically responsive beads in liquid portions or droplets in digital microfluidics and a disposable cartridge to carry out the methods.

公开(公告)号：US20180200711A1

公开(公告)日：2018-07-19

申请号：US15918798

申请日：2018-03-12

申请人： STEMCELL TECHNOLOGIES INC

发明人： Oliver Egeler ,  Steven Woodside

IPC分类号： B01L3/00

CPC分类号： B01L3/508 ,  B01L3/5085 ,  B01L2200/026 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/165 ,  B01L2300/166 ,  C12M1/00 ,  C12M23/04 ,  C12M23/12 ,  C12M23/20 ,  C12M41/36

摘要： A meniscus reducing member for use in a vessel for containing a liquid may include a physical surface feature overlying at least a portion of an interior surface of the vessel. The physical surface feature may have first and second inner surfaces that are generally parallel and at least a third surface extending between the first and second surfaces. The first inner surface, second inner surface and third surfaces may be configured to physically alter a receding contact angle between the liquid and the physical surface feature. A coating material may be applied to at least one of the surfaces of the physical surface feature to chemically alter the receding contact angle between the liquid and the coated surface whereby the receding contact angle formed between the liquid and the meniscus reducing member is between about 90 degrees and less than 180 degrees.

公开(公告)号：US20180195937A1

公开(公告)日：2018-07-12

申请号：US15911660

申请日：2018-03-05

申请人： Lee H. Angros

发明人： Lee H. Angros

IPC分类号： G01N1/30 ,  B05D1/28 ,  B05D7/00 ,  B01L3/00 ,  B01L99/00 ,  B05C1/02 ,  B05C13/02 ,  B05D1/02 ,  B05D1/20 ,  B05C11/02 ,  B01L3/02 ,  B05C9/06 ,  B05C9/14

CPC分类号： G01N1/30 ,  B01L3/0258 ,  B01L3/508 ,  B01L99/00 ,  B01L2200/12 ,  B01L2300/0822 ,  B01L2300/16 ,  B01L2300/161 ,  B05C1/025 ,  B05C9/06 ,  B05C9/14 ,  B05C11/028 ,  B05C13/02 ,  B05D1/02 ,  B05D1/20 ,  B05D1/28 ,  B05D7/5483 ,  B05D2252/04 ,  G01N2001/305 ,  Y10T156/179 ,  Y10T156/1798

摘要： An apparatus and method for producing a coated analytic substrate using a compact and portable automated instrument located in the laboratory setting at the point of use which can consistently produce one or a plurality of coated analytic substrates “on demand” for using the analytic substrate immediately after coating, preferably without a step of rinsing the coated analytic substrate before use. The apparatus preferably uses applicator cartridges having a reservoir containing the coating compositions used to form the coatings. Preferably the cartridges are removable and interchangeable to facilitate the production of individual analytic substrates having different coatings or different coating patterns. These coated analytic substrates have superior specimen adhesion characteristics due to the improved quality of the coatings applied by the coating apparatus and due to the quickness with which the coated analytic substrates can be used in the lab after production.

公开(公告)号：US09976946B2

公开(公告)日：2018-05-22

申请号：US15134528

申请日：2016-04-21

申请人： Instrumentation Laboratory Company

发明人： Brian Joseph Bosy ,  Josef Kerimo

IPC分类号： G01N21/01 ,  G01N21/05 ,  G01N21/27 ,  G01N21/03 ,  G01N33/49

CPC分类号： G01N21/05 ,  B01L3/508 ,  B01L2200/0689 ,  B01L2300/0822 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/27 ,  G01N33/4915 ,  G01N2021/058 ,  G01N2021/115 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/0668

摘要： A sample cell apparatus for use in spectroscopic determination of an analyte in a body fluid sample includes a first plate member made from an optically clear material and a second plate member made from an optically clear material and opposing the first plate member. A channel extending into a surface of the first plate member and an opposing surface of the second plate member houses a floating seal. The floating seal surrounds a fluid chamber that retains a sample of body fluid for optical measurement. The fluid chamber may be opened for flushing by separating the first plate member from the second plate member. During measurements the fluid chamber is closed to define a repeatable optical path-length therethrough by urging the first plate member against the second plate member without compressing the floating seal between the first plate member and the second plate member.