公开(公告)号：US20190071314A1

公开(公告)日：2019-03-07

申请号：US16122872

申请日：2018-09-05

Applicant: LEMONEX INC. ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Dal-Hee MIN ,  Cheolhee WON ,  Sejin PARK ,  Seongchan KIM

IPC: C01B37/02 ,  C12N5/00 ,  A61K9/50 ,  A61K9/51 ,  B01J13/02 ,  B82Y5/00

Abstract: A composition includes porous silica particles to carry a cell fate modulating factor therein. A method for modulating cell fate includes treating various cells with the composition. The cell fate modulating factor is delivered to a stable target receptor, toxicity to subject cells for delivery may be reduced, a fate of the subject cells can be controlled through sustained release of at least 99 wt. % of the cell fate modulating factor.