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1.
公开(公告)号:US20230373984A1
公开(公告)日:2023-11-23
申请号:US18251084
申请日:2021-10-29
申请人: LG CHEM, LTD.
发明人: Jin Ok HAM , Ho Yeon LEE , Ji Yoon KIM , Sung Won KIM , Seul Ah CHUN , Sang Dae LEE , Jong Won PARK
IPC分类号: C07D413/14
CPC分类号: C07D413/14 , C07B2200/13
摘要: The present invention relates to a crystalline form I represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form I represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.
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公开(公告)号:US20240317716A1
公开(公告)日:2024-09-26
申请号:US18575570
申请日:2022-07-01
申请人: LG CHEM, LTD.
发明人: Seok Ju LEE , Hui Rak JEONG , Jin Ok HAM , Doo Sup SHIN
IPC分类号: C07D403/04
CPC分类号: C07D403/04
摘要: The present invention relates to a method for preparing a xanthine oxidase inhibitor and, more specifically, to a method for preparing a compound of chemical formula 2 by using ester hydrolysis and a recrystallization method.
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3.
公开(公告)号:US20240051944A1
公开(公告)日:2024-02-15
申请号:US18258717
申请日:2021-12-22
申请人: LG CHEM, LTD.
发明人: Ji Yoon KIM , Ho Yeon LEE , Jin Ok HAM , Seul Ah CHUN , Sung Won KIM
IPC分类号: C07D403/06
CPC分类号: C07D403/06 , C07B2200/13
摘要: The present invention relates to a crystalline form II represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form II represented by formula 1 of the present invention may be characterized by XRPD patterns, DSC profiles, TGA profiles, and/or DVS profiles.
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4.
公开(公告)号:US20240002322A1
公开(公告)日:2024-01-04
申请号:US18248721
申请日:2021-10-12
申请人: LG CHEM, LTD.
发明人: Sung Wook KIM , Ki Dae KIM , Soo Min LEE , Ho Yeon LEE , Jin Ok HAM
CPC分类号: C07C45/676 , C07B2200/13 , C07C67/29
摘要: The present invention relates to a novel method for producing an intermediate expressed by chemical formula 5 that can be effectively used in synthesis of sphingosine-1-phosphate receptor agonist.
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5.
公开(公告)号:US20230399321A1
公开(公告)日:2023-12-14
申请号:US18251101
申请日:2021-10-29
申请人: LG CHEM, LTD.
发明人: Jin Ok HAM , Ho Yeon LEE , Ji Yoon KIM , Sung Won KIM , Seul Ah CHUN , Sang Dae LEE , Jong Won PARK
IPC分类号: C07D413/14
CPC分类号: C07D413/14 , C07B2200/13
摘要: The present invention relates to a crystalline form II represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form II represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.
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6.
公开(公告)号:US20240043407A1
公开(公告)日:2024-02-08
申请号:US18258711
申请日:2021-12-22
申请人: LG CHEM, LTD.
发明人: Ji Yoon KIM , Sang Dae LEE , Ri Ra KIM , Sung Won KIM , Ho Yeon LEE , Seul Ah CHUN , Jin Ok HAM
IPC分类号: C07D403/06
CPC分类号: C07D403/06 , C07B2200/13
摘要: The present invention relates to a crystalline form I represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form I represented by formula 1 of the present invention may be characterized by XRPD patterns, DSC profiles, TGA profiles, and/or DVS profiles.
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7.
公开(公告)号:US20240010633A1
公开(公告)日:2024-01-11
申请号:US18251111
申请日:2021-10-29
申请人: LG CHEM, LTD.
发明人: Jin Ok HAM , Ho Yeon LEE , Ji Yoon KIM , Sung Won KIM , Seul Ah CHUN , Sang Dae LEE , Jong Won PARK
IPC分类号: C07D403/06
CPC分类号: C07D403/06 , C07B2200/13
摘要: The present invention relates to a crystalline form IV represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form IV represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.
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8.
公开(公告)号:US20240239783A1
公开(公告)日:2024-07-18
申请号:US18558148
申请日:2022-05-06
申请人: LG CHEM, LTD.
发明人: Ho Yeon LEE , Jin Ok HAM , Sang Dae LEE , Ji Yoon KIM , Jong Won PARK , Sung Won KIM , Seul Ah CHUN
IPC分类号: C07D413/14 , A61K31/5377
CPC分类号: C07D413/14 , A61K31/5377
摘要: The present invention relates to a crystal form VII of a compound represented by chemical formula 1, a method for preparing same, and a pharmaceutical composition comprising same. The crystal form VII of the compound represented by chemical formula 1, according to the present invention, can be characterized by an XRD pattern, a DSC profile, and/or a TGA profile.
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9.
公开(公告)号:US20240228473A1
公开(公告)日:2024-07-11
申请号:US18557866
申请日:2022-05-06
申请人: LG CHEM, LTD.
发明人: Jin Ok HAM , Ho Yeon LEE , Sang Dae LEE , Ji Yoon KIM , Jong Won PARK , Sung Won KIM , Seul Ah CHUN
IPC分类号: C07D413/14 , A61K31/5377
CPC分类号: C07D413/14 , A61K31/5377
摘要: The present invention relates to a crystalline form V of a compound represented by chemical formula 1, a method for preparing same, and a pharmaceutical composition comprising same. Crystalline form V of the compound represented by chemical formula 1 according to the present invention may be characterized by an XRD pattern, a DSC profile, and/or a TGA profile.
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10.
公开(公告)号:US20230382895A1
公开(公告)日:2023-11-30
申请号:US18251129
申请日:2021-10-29
申请人: LG CHEM, LTD.
发明人: Jin Ok HAM , Ho Yeon LEE , Ji Yoon KIM , Sung Won KIM , Seul Ah CHUN , Sang Dae LEE , Jong Won PARK
IPC分类号: C07D403/06
CPC分类号: C07D403/06 , C07B2200/13
摘要: The present invention relates to a crystalline form III represented by formula 1, a method for preparing the same, and a pharmaceutical composition comprising the same. The crystalline form III represented by formula 1 of the present invention may be characterized by XRD patterns, DSC profiles, and/or TGA profiles.
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