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公开(公告)号：US20210170643A1
公开(公告)日：2021-06-10
申请号：US16764312
申请日：2018-07-05
发明人： Young-Min HWANG , Koo-Chul KWON , Woo-Sun SHIM , Nae-Gyu KANG
摘要： The present disclosure relates to an apparatus and a process which can continuously produce microneedles using a conveyor system and decomposition or vacuum. By using the microneedle production method and apparatus according to the present disclosure, continuous mass production of microneedles is available, and therefore it is possible to reduce the input of manpower and produce a large amount of products compared to the conventional production method.
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公开(公告)号：US20200222299A1
公开(公告)日：2020-07-16
申请号：US16648457
申请日：2017-09-19
发明人： Jun-Seok YEOM , Woo-Sun SHIM , Young-Min HWANG , Seung-Min YOO , Seol-Hoon LEE , Nae-Gyu KANG
摘要： The present disclosure relates to a soluble microneedle and a filler composition with an excellent anti-wrinkle effect. Using the microneedle according to the present disclosure, crosslinked hyaluronic acid (hyaluronic acid filler material) can be intradermally or subcutaneously administered by a simple method, and a swelling property of the crosslinked hyaluronic acid is improved after administration, thereby exhibiting the excellent anti-wrinkle effect.
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公开(公告)号：US20180116938A1
公开(公告)日：2018-05-03
申请号：US15565114
申请日：2016-04-06
发明人： Woo-Sun SHIM , Sun-Hwa LEE , Young-Min HWANG , Nae-Gyu KANG
CPC分类号： A61K8/64 , A61K8/02 , A61K8/027 , A61K8/731 , A61K8/735 , A61K8/85 , A61K9/0021 , A61K9/0024 , A61K9/1647 , A61K9/70 , A61K9/7023 , A61K38/18 , A61K38/1808 , A61K2800/412 , A61M37/00 , A61M37/0015 , A61Q19/08
摘要： The present invention relates to a skin administration system capable of ensuring the stability of peptides or proteins and enhancing the delivery rate of peptides or proteins through the skin and, more particularly, to a microneedle comprising peptides or proteins.
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公开(公告)号：US20200324096A1
公开(公告)日：2020-10-15
申请号：US16766544
申请日：2018-07-05
发明人： Young-Min HWANG , Woo-Sun SHIM , Nae-Gyu KANG
摘要： The present disclosure relates to a method for manufacturing a microneedle containing a coating part on a needle tip and an apparatus used for the method. When a microneedle is manufactured using the coating method and apparatus according to the present disclosure, a coating part in which a target material is impregnated can be easily inserted into skin and effective dissolution is possible. Further, the target material is allowed to show excellent skin permeability with the dissolution of the coating part of the microneedle manufactured according to the present disclosure, thereby a quantitative amount of target material can be effectively delivered into the skin.
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公开(公告)号：US20180071208A1
公开(公告)日：2018-03-15
申请号：US15564544
申请日：2016-04-06
发明人： Woo-Sun SHIM , Sun-Hwa LEE , Young-Min HWANG , Jung-A KIM , Nae-Gyu KANG
CPC分类号： A61K9/0021 , A61K8/027 , A61K8/0275 , A61K8/14 , A61K8/347 , A61K8/498 , A61K8/731 , A61K8/735 , A61K8/85 , A61K9/141 , A61K9/1641 , A61K9/1647 , A61K9/7023 , A61K31/122 , A61K31/352 , A61K2800/412 , A61M37/0015 , A61M2037/0053 , A61Q19/08
摘要： The present invention relates to a system for administering a poorly-soluble compound to the skin, the system being capable of exerting an excellent effect by stably impregnating the poorly-soluble compound and effectively delivering the poorly-soluble compound into the skin, and the present invention is technically characterized by a microneedle to which microparticles comprising a poorly-soluble compound are added. In addition, the present invention provides a method for administering a poorly-soluble compound to the skin, the method being characterized by using the microneedle.
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公开(公告)号：US20170209391A1
公开(公告)日：2017-07-27
申请号：US15328233
申请日：2015-04-23
发明人： Woo-Sun SHIM , Dong-Chan KIM , Young-Min HWANG , Sun-Hwa LEE , Nae-Gyu KANG , Sun-Gyoo PARK , Cheon-Koo LEE
CPC分类号： A61K31/07 , A61K9/0021 , A61K9/16 , A61K9/1641 , A61K9/1647 , A61K47/10 , A61K47/26 , A61K47/36 , A61K47/38 , A61M37/0015 , A61M2037/0023 , A61M2037/0053 , A61M2037/0061
摘要： The present disclosure relates to a system for administering retinol into skin that ensures stability of retinol, reduces skin irritation of retinol, and continues to exert effects, wherein the system is a microneedle including microparticles containing retinol or retinol derivatives. The present disclosure further provides a method for manufacturing a retinol administration system that reduces skin irritation, exerts effects of retinol for a long time, and ensures stability of retinol very unstable to light, wet and temperature. The present disclosure further provides a method for administering retinol into skin using the microneedle.
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