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公开(公告)号:US20130218476A1
公开(公告)日:2013-08-22
申请号:US13850287
申请日:2013-03-25
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Francis CHENG , Chengyong YANG , Casey McFARLAND , Ying WANG
CPC classification number: G16B99/00 , C12Q1/68 , C12Q1/6827 , G01N21/64 , G01N25/04 , G01N25/48 , G16B40/00 , C12Q2527/107 , C12Q2537/165 , C12Q2563/173
Abstract: The present application provides for various embodiments of methods for the analysis of high resolution melt (HRM) curve data; where statistical assay variations in melt curve data may result from system noise in an analysis system. Such system noise may arise from various sources, such as the thermal non-uniformity of a thermocycler block in a thermal cycler apparatus, a detection system, etc. Additionally, various methods for the analysis of HRM curve data may provide an identification of a sample without the need for a user inputted information.
Abstract translation: 本申请提供了用于分析高分辨率熔体(HRM)曲线数据的方法的各种实施方案; 其中熔体曲线数据的统计测定变化可能由分析系统中的系统噪声引起。 这种系统噪声可能来自各种来源,例如热循环仪装置中的热循环器块的热不均匀性,检测系统等。另外,用于分析HRM曲线数据的各种方法可以提供样品的鉴定 而不需要用户输入的信息。