公开(公告)号：US20230407391A1

公开(公告)日：2023-12-21

申请号：US18209766

申请日：2023-06-14

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Steven M. MENCHEN ,  Alan BLANCHARD ,  Luisa ANDRUZZI ,  Shaheer KHAN ,  Dmitriy GREMYACHINSKIY ,  Alfred LUI ,  Craig STOLARCZYK ,  Tanya SOKOLSKY ,  Prasanna Krishnan THWAR

IPC: C12Q1/6876 ,  C12Q1/6834 ,  C08F8/40

CPC classification number: C12Q1/6876 ,  C12Q1/6834 ,  C08F8/40

Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.

公开(公告)号：US20180223359A1

公开(公告)日：2018-08-09

申请号：US15945348

申请日：2018-04-04

Applicant: Life Technologies Corporation

Inventor： Steven M. MENCHEN ,  Alan BLANCHARD ,  Luisa ANDRUZZI ,  Shaheer H. KHAN ,  Dmitriy GREMYACHINSKIY ,  Alfred LUI ,  Craig STOLARCZYK ,  Tanya SOKOLSKY ,  Prasanna Krishnan THWAR

IPC: C12Q1/6876 ,  C08F8/40 ,  C12Q1/6834

Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.