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公开(公告)号:US20190390229A1
公开(公告)日:2019-12-26
申请号:US16095147
申请日:2017-04-20
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Robert Jason POTTER , Jason CARTER
Abstract: The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR reagents and the use of such reagents. Further disclosed are nucleic acid compositions with reduced cytotoxicity.