公开(公告)号：US09879283B2

公开(公告)日：2018-01-30

申请号：US14879872

申请日：2015-10-09

Applicant: LIFE TECHNOLOGIES CORPORATION ,  THERMO FISHER SCIENTIFIC GENEART GMBH

Inventor： Namritha Ravinder ,  Korbinian Heil ,  Yizhu Guo ,  Xiquan Liang ,  Robert Potter ,  Sanjay Kumar

IPC: C12Q1/68 ,  C12N15/90 ,  C12N15/10 ,  C12P19/34 ,  C12N15/11

CPC classification number: C12N15/907 ,  C12N15/102 ,  C12N15/11 ,  C12N2310/3519 ,  C12P19/34 ,  C12Q1/686 ,  C12Q2525/143

Abstract: The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR reagents and the use of such reagents.

公开(公告)号：US10428327B2

公开(公告)日：2019-10-01

申请号：US15605586

申请日：2017-05-25

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Xiquan Liang ,  Robert Potter ,  Namritha Ravinder

IPC: C12N15/10 ,  C12N15/113 ,  C12N15/90

Abstract: The present disclosure generally relates to compositions and methods for improving the efficiency of homologous recombination. In particular, the disclosure relates to reagents and the use of such reagents.

公开(公告)号：US20160102322A1

公开(公告)日：2016-04-14

申请号：US14879872

申请日：2015-10-09

Applicant: LIFE TECHNOLOGIES CORPORATION ,  THERMO FISHER SCIENTIFIC GENEART GMBH

Inventor： Namritha Ravinder ,  Korbinian Heil ,  Yizhu Guo ,  Xiquan Liang ,  Robert Potter

IPC: C12N15/90 ,  C12N15/11 ,  C12P19/34

CPC classification number: C12N15/907 ,  C12N15/102 ,  C12N15/11 ,  C12N2310/3519 ,  C12P19/34 ,  C12Q1/686 ,  C12Q2525/143

Abstract: The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR reagents and the use of such reagents.

Abstract translation: 本公开一般涉及用于细胞遗传修饰的组合物和方法。 特别地，本公开涉及CRISPR试剂和这些试剂的用途。