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公开(公告)号:US11566221B2
公开(公告)日:2023-01-31
申请号:US16344497
申请日:2017-10-20
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Soojung Shin , Yiping Yan , Daniel Beacham
IPC: C12N5/0793 , C12N5/00 , C12N5/0735 , C12N5/074
Abstract: Embodiments herein provide methods of differentiating neural stem cells to neuronal cells while concomitantly retarding neural stem cell proliferation. Resultant cultures demonstrate reduced clumping of cells, increased purity of neuronal cells and accelerated electrophysiology as compared to control methods.