公开(公告)号：US20220026365A1

公开(公告)日：2022-01-27

申请号：US17378479

申请日：2021-07-16

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Mark F. Oldham ,  Eric S. Nordman ,  Hongye Sun ,  Steven Boege

IPC: G01N21/64

Abstract: A scanning detection system is provided wherein emissions from locations in a flow cell are detected. In some embodiments, the system can comprise an excitation source, a photocleavage source, and modulating optics configured to cause an excitation beam generated by the excitation source to irradiate a first group of the fixed locations and to cause a photocleavage beam generated by the photocleavage source to irradiate a second group of the fixed locations, which is separate and apart from the first group of fixed locations. Methods of detecting sequencing reactions using such a system are also provided.

公开(公告)号：US11092548B2

公开(公告)日：2021-08-17

申请号：US16155831

申请日：2018-10-09

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Mark F. Oldham ,  Eric S. Nordman ,  Hongye Sun ,  Steven Boege

IPC: G01N21/00 ,  G01N21/64

Abstract: A scanning detection system is provided wherein emissions from locations in a flow cell are detected. In some embodiments, the system can comprise an excitation source, a photocleavage source, and modulating optics configured to cause an excitation beam generated by the excitation source to irradiate a first group of the fixed locations and to cause a photocleavage beam generated by the photocleavage source to irradiate a second group of the fixed locations, which is separate and apart from the first group of fixed locations. Methods of detecting sequencing reactions using such a system are also provided.