公开(公告)号：US20210009329A1

公开(公告)日：2021-01-14

申请号：US16633995

申请日：2018-07-21

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Klaus Schumann ,  Rolf Böhm ,  Torsten Grunenberg ,  Bernd Grünes ,  Markus Bee ,  Anna Schlüter

IPC: B65D75/30 ,  B29C65/00

Abstract: Provided is a method for producing a sealed-edge pouch with a laminate composite stored therein. In some non-limiting embodiments or aspects the laminate composite is detached from a laminate composite web having a carrier film with substrates which are arranged thereon and are covered by means of a respective cover film. An intermediate body is supplied to the laminate composite web or to the laminate composite or is moulded into the carrier film such that the intermediate body or the intermediate bodies surrounds/surround all of the free surfaces of the substrate at least in regions. The laminate composite and all of the intermediate bodies are introduced between two packaging material webs. The packaging material webs are sealed to each other. Finally, the sealed-edge pouches are separated. A device for producing sealed-edge pouches and a sealed-edge pouch produced according to this method are also provided.

公开(公告)号：US11801986B2

公开(公告)日：2023-10-31

申请号：US16633995

申请日：2018-07-21

Applicant: LTS Lohmann Therapie—Systeme AG

Inventor： Klaus Schumann ,  Rolf Böhm ,  Torsten Grunenberg ,  Bernd Grünes ,  Markus Bee ,  Anna Schlüter

IPC: B65D75/30 ,  B29C65/00 ,  B29L31/00

CPC classification number: B65D75/30 ,  B29C66/1122 ,  B29C66/849 ,  B29L2031/7128

Abstract: Provided is a method for producing a sealed-edge pouch with a laminate composite stored therein. In some non-limiting embodiments or aspects the laminate composite is detached from a laminate composite web having a carrier film with substrates which are arranged thereon and are covered by means of a respective cover film. An intermediate body is supplied to the laminate composite web or to the laminate composite or is moulded into the carrier film such that the intermediate body or the intermediate bodies surrounds/surround all of the free surfaces of the substrate at least in regions. The laminate composite and all of the intermediate bodies are introduced between two packaging material webs. The packaging material webs are sealed to each other. Finally, the sealed-edge pouches are separated. A device for producing sealed-edge pouches and a sealed-edge pouch produced according to this method are also provided.

公开(公告)号：US20200009073A1

公开(公告)日：2020-01-09

申请号：US16577473

申请日：2019-09-20

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Reinhold Meconi ,  Klaus Schumann

IPC: A61K9/70

Abstract: The present invention is directed to transdermal therapeutic systems that are free of fibrous constituents, as well methods for producing such transdermal therapeutic systems. A preparation containing active substance is applied by a printing method onto the pressure-sensitive adhesive layer of the transdermal therapeutic system. Exemplary printing methods include application methods based upon a distributor plate of an application device.

公开(公告)号：US11478434B2

公开(公告)日：2022-10-25

申请号：US16577473

申请日：2019-09-20

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Reinhold Meconi ,  Klaus Schumann

IPC: A61K9/70 ,  A61K31/196 ,  A61K31/21 ,  A61K31/565 ,  A61K31/465

Abstract: The present invention is directed to transdermal therapeutic systems that are free of fibrous constituents, as well methods for producing such transdermal therapeutic systems. A preparation containing active substance is applied by a printing method onto the pressure-sensitive adhesive layer of the transdermal therapeutic system. Exemplary printing methods include application methods based upon a distributor plate of an application device.

公开(公告)号：US11439807B2

公开(公告)日：2022-09-13

申请号：US16657147

申请日：2019-10-18

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Mohammad Sameti ,  Ronald Hackbarth ,  Klaus Schumann ,  Christoph Schmitz

IPC: A61N1/04 ,  A61K31/27 ,  A61K31/4468 ,  A61K31/485 ,  A61K31/55 ,  A61K38/22 ,  A61K38/27 ,  A61K38/28 ,  A61K38/36 ,  A61M37/00 ,  A61N1/30

Abstract: The invention relates to a transdermal therapeutic system (TTS) for delivering pharmaceutical active ingredients. The TTS includes a cover layer and at least one active-ingredient-containing carrier material. At least one retaining element is located between the active-ingredient-containing carrier material and the cover layer, with the retaining element fixing the active-ingredient-containing carrier material onto the cover layer. The invention further relates to a method for fastening an active-ingredient-containing carrier material to a cover layer of a TTS in the presence of hook-and-loop strip segments and the use of a hook-and-loop strip in transdermal or iontophoretic administration of pharmaceutical or therapeutic active ingredients to patients.