公开(公告)号：US20190125692A1

公开(公告)日：2019-05-02

申请号：US16094933

申请日：2017-04-20

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Markus MÜLLER ,  Claudia Maria HAMMES ,  Christoph SCHMITZ ,  Michael LINN ,  Mohammad SAMETI ,  Peter KLAFFENBACH

IPC: A61K9/70 ,  A61K38/28 ,  A61K9/00 ,  A61K47/38

Abstract: The invention relates to film-like forms of administration for the transmucosal delivery of antidiabetic peptides via the oral mucosa and to processes for the production thereof Antidiabetic peptides refers to peptides which are an active compound for the treatment of diabetes mellitus, and includes insulins, insulin analogs, incretins and incretin mimetics.

公开(公告)号：US20200046963A1

公开(公告)日：2020-02-13

申请号：US16657147

申请日：2019-10-18

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Mohammad SAMETI ,  Ronald HACKBARTH ,  Klaus SCHUMANN ,  Christoph SCHMITZ

IPC: A61N1/04 ,  A61K31/27 ,  A61K31/4468 ,  A61K31/485 ,  A61K31/55 ,  A61K38/22 ,  A61K38/27 ,  A61K38/28 ,  A61K38/36 ,  A61M37/00 ,  A61N1/30

Abstract: The invention relates to a transdermal therapeutic system (TTS) for delivering pharmaceutical active ingredients. The TTS includes a cover layer and at least one active-ingredient-containing carrier material. At least one retaining element is located between the active-ingredient-containing carrier material and the cover layer, with the retaining element fixing the active-ingredient-containing carrier material onto the cover layer. The invention further relates to a method for fastening an active-ingredient-containing carrier material to a cover layer of a TTS in the presence of hook-and-loop strip segments and the use of a hook-and-loop strip in transdermal or iontophoretic administration of pharmaceutical or therapeutic active ingredients to patients.

公开(公告)号：US20190231710A1

公开(公告)日：2019-08-01

申请号：US16380069

申请日：2019-04-10

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Michael HORSTMANN ,  Mohammad SAMETI ,  Tobias JUNG

IPC: A61K9/70

Abstract: The present invention relates to a transdermal therapeutic system, preferably a transdermal patch, having an active ingredient-containing matrix formed substantially of a water-insoluble base material, such as rubber and synthetic polymers, into which is incorporated water-soluble and/or water-swellable inclusion bodies, e.g. inclusion bodies formed from polyvinyl alcohol or polyethylene glycol, that further include micronized or nanoscale active ingredient particles.

公开(公告)号：US20160303361A1

公开(公告)日：2016-10-20

申请号：US15105821

申请日：2014-12-17

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Mohammad SAMETI ,  Ronald HACKBARTH ,  Klaus SCHUMANN ,  Christoph SCHMITZ

IPC: A61N1/04 ,  A61M37/00 ,  A61K31/4468 ,  A61K31/485 ,  A61K38/36 ,  A61K31/55 ,  A61K38/28 ,  A61K38/22 ,  A61K38/27 ,  A61N1/30 ,  A61K31/27

CPC classification number: A61N1/0448 ,  A61K31/27 ,  A61K31/4468 ,  A61K31/485 ,  A61K31/55 ,  A61K38/2271 ,  A61K38/27 ,  A61K38/28 ,  A61K38/36 ,  A61M37/00 ,  A61M2037/0007 ,  A61M2207/00 ,  A61N1/0428 ,  A61N1/0436 ,  A61N1/303

Abstract: The invention relates to a transdermal therapeutic system (TTS) for delivering pharmaceutical active ingredients. The TTS includes a cover layer and at least one active-ingredient-containing carrier material. At least one retaining element is located between the active-ingredient-containing carrier material and the cover layer, with the retaining element fixing the active-ingredient-containing carrier material onto the cover layer. The invention further relates to a method for fastening an active-ingredient-containing carrier material to a cover layer of a TTS in the presence of hook-and-loop strip segments and the use of a hook-and-loop strip in transdermal or iontophoretic administration of pharmaceutical or therapeutic active ingredients to patients.

Abstract translation: 本发明涉及用于递送药物活性成分的透皮治疗系统（TTS）。 TTS包括覆盖层和至少一种含活性成分的载体材料。 至少一个保持元件位于含活性成分的载体材料和覆盖层之间，保持元件将含活性成分的载体材料固定到覆盖层上。 本发明还涉及一种用于在存在钩和环带段的情况下将含活性成分的载体材料紧固到TTS的覆盖层的方法，以及在透皮或离子电渗疗法中使用钩环条带 向患者施用药物或治疗活性成分。