公开(公告)号：US20190336454A1

公开(公告)日：2019-11-07

申请号：US16445582

申请日：2019-06-19

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine.

公开(公告)号：US20220323370A1

公开(公告)日：2022-10-13

申请号：US17660313

申请日：2022-04-22

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70 ,  A61K31/407

Abstract: The present invention relates to a transdermal therapeutic system (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure comprising a therapeutically effective amount of asenapine, said self-adhesive layer structure comprising: A) a backing layer; B) an asenapine-containing layer comprising: 1. asenapine in the form of the free base; and 2. a polymer selected from the group consisting of polysiloxanes and polyisobutylenes in an amount of more than 50% by weight based on the total weight of the asenapine-containing layer; and C) optionally an additional skin contact layer.

公开(公告)号：US20220241216A1

公开(公告)日：2022-08-04

申请号：US17597387

申请日：2020-07-08

Applicant: LTS LOHMANN THERAPIE-SYSTEME AG

Inventor： Marco EMGENBROICH ,  Peter KLAFFENBACH ,  Nico REUM ,  Gabriel WAUER ,  Patrick MOHR ,  Anna SCHLÜTER ,  Hans-Werner WOLF

IPC: A61K9/70 ,  A61K47/32 ,  A61K31/325 ,  A61F13/02 ,  A61F13/00

Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of an active agent comprising an active agent-containing layer structure, said active agent-containing layer structure comprising: A) a backing layer; B) an active agent-containing layer comprising at least one acrylic polymer; C) a skin contact layer; and wherein the skin contact layer is an adhesive layer comprising a silicone gel adhesive.

公开(公告)号：US20200179298A1

公开(公告)日：2020-06-11

申请号：US16623034

申请日：2018-06-25

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70 ,  A61K31/407 ,  A61P25/18

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising an asenapine-containing layer structure, said asenapine-containing layer structure comprising A) a backing layer and B) an asenapine-containing layer, wherein the transdermal therapeutic system comprises a silicone acrylic hybrid polymer.

公开(公告)号：US20200085759A1

公开(公告)日：2020-03-19

申请号：US16470322

申请日：2017-12-19

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70 ,  A61K31/407

Abstract: The present invention relates to a transdermal therapeutic system (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure comprising a therapeutically effective amount of asenapine, said self-adhesive layer structure comprising: A) a backing layer; B) an asenapine-containing layer comprising: 1. asenapine in the form of the free base; and 2. a polymer selected from the group consisting of polysiloxanes and polyisobutylenes in an amount of more than 50% by weight based on the total weight of the asenapine-containing layer; and C) optionally an additional skin contact layer.

公开(公告)号：US20190134254A1

公开(公告)日：2019-05-09

申请号：US16239862

申请日：2019-01-04

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Michael HORSTMANN ,  Christian HAUSEN ,  Patrick MOHR ,  Karin LUDWIG ,  Tobias KLEUDGEN

IPC: A61L15/44 ,  A61L15/58 ,  A61L15/24

Abstract: The present invention relates to adhesive bandages provided with a water-vapor permeable back layer and an adhesive layer, in which the adhesive layer includes 10 weight percent of a disperse internal phase of hydrophilic particles that are water-swellable in an outer phase that includes at least 10 weight percent of a styrene block copolymer and at least 20 weight percent of an ester resin of colophony, and that can further contain at least one anti-virus substance.

公开(公告)号：US20240374544A1

公开(公告)日：2024-11-14

申请号：US18686139

申请日：2022-08-29

Applicant: LTS LOHMANN THERAPIE-SYSTEME AG

Inventor： Eva-Marie PRINZ ,  Marco EMGENBROICH ,  Patrick MOHR ,  Stefan LORSCHEIDT

IPC: A61K31/155 ,  A61K9/70 ,  A61K47/10 ,  A61K47/12 ,  A61K47/32 ,  A61K47/34

Abstract: The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising guanfacine and a mono-carboxylic acid.

公开(公告)号：US20240285546A1

公开(公告)日：2024-08-29

申请号：US17786217

申请日：2020-10-02

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70 ,  A61K9/00 ,  A61K31/165 ,  A61K47/32 ,  A61P25/24

CPC classification number: A61K9/7069 ,  A61K9/0014 ,  A61K31/165 ,  A61K47/32 ,  A61P25/24

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of agomelatine comprising a self-adhesive layer structure containing a therapeutically effective amount of agomelatine, such agomelatine TTS for use in a method of treatment, a method of treatment comprising applying such agomelatine TTS, and processes of manufacture of such TTS.

公开(公告)号：US20210330601A1

公开(公告)日：2021-10-28

申请号：US17195267

申请日：2021-03-08

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70 ,  A61K31/407

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine.

公开(公告)号：US20210251914A1

公开(公告)日：2021-08-19

申请号：US17250162

申请日：2019-06-19

Applicant: LTS LOHMANN THERAPIE-SYSTEME AG

Inventor： Patrick MOHR ,  René RIETSCHER ,  René EIFLER ,  Olga BOURQUAIN

IPC: A61K9/70 ,  A61K31/407

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine.