摘要:
A vascular stent having one or more channels in the outer surface. The channel(s) provide increased flexibility, enhanced perfusion, increased chronic positional stability, and convenient dispensing of a medication. Preferably the stent is machined into a mesh-like pattern and the channel(s) are machined into the stent elements of the pattern. The channels may be oriented in a variety of ways. Parallel orientation tends to provide greater enhancement of perfusion whereas perpendicular orientation provides differential flexibility. For greater control of differential flexibility, the channel may be further machined in the stent element, producing a regain of greater flexibility.
摘要:
A mass and heat exchanger includes at least one first substrate with a surface for supporting a continuous flow of a liquid thereon that either absorbs, desorbs, evaporates or condenses one or more gaseous species from or to a surrounding gas; and at least one second substrate operatively associated with the first substrate. The second substrate includes a surface for supporting the continuous flow of the liquid thereon and is adapted to carry a heat exchange fluid therethrough, wherein heat transfer occurs between the liquid and the heat exchange fluid.
摘要:
Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.
摘要:
A nucleic acid probe assay which combines nucleic acid amplification with solution hybridization using capture and reporter probes followed by or simultaneously with immobilization on a solid support is provided. An assay sensitivity equal to 5 copies of HIV I DNA was achieved.
摘要翻译:提供了一种核酸探针测定法,其使用捕获和报道探针将核酸扩增与溶液杂交结合在一起,同时固定在固体支持物上。 获得等于5拷贝的HIV I DNA的测定灵敏度。
摘要:
Envelope viruses (e.g. Newcastle disease virus (NDV)) are formulated for storage at moderately cold temperatures (e.g. −20° C.). The formulation is an aqueous solution containing the enveloped virus at a concentration of from 106 PFU/mL to 1012 PFU/mL; and a non-reducing saccharide (e.g. sucrose). When the non-reducing saccharide is a disaccharide it is present in the solution at a concentration of from 5% (w/v) to 50% (w/v), and when it is a monosaccharide it is present in the solution at a concentration of from 2.5% (w/v) to 25% (w/v). The solution has an osmotic pressure of about 250 mOs or higher, and has a pH of from 5 to 10.
摘要:
A method of treating a human subject with cancer is disclosed. A pharmaceutical composition is administered to the subject, the pharmaceutical composition comprising human leukocytes and a replication-competent oncolytic virus in suspension in a physiologically acceptable solution. Alternatively the pharmaceutical composition comprises human leukocytes or platelets infected with an oncolytic virus.
摘要:
According to one embodiment of the present invention an electrolyte sheet includes a body of varied thickness, the electrolyte sheet having a textured surface with multiple protruding features. The protruding features form an undercut angle with respect to the normal of the electrolyte sheet, the undercut angle being more than 0 degrees and less than 15 degrees.
摘要:
A circuit breaker contact assembly includes a line conductor having a folded back fixed contact end, a fixed contact mounted on the contact end, and a movable contact arm having an inner edge and first and second ends. A movable contact is mounted on the first end. The movable contact arm is pivotable about the second end between a closed position in which the inner edge extends adjacent the contact end with the movable contact in contact with the fixed contact to form a reverse current loop, and an open position in which the movable contact is pivoted away from the fixed contact. The contact arm includes a first inner longitudinal member extending along the inner edge and a second outer longitudinal member. The first inner longitudinal member has a higher electrical conductivity than the second outer longitudinal member, which has a higher shear strength and a lower specific density.
摘要:
The support for the moving contact of a circuit breaker has a piston that is driven by arc gases generated by initial separation of the contacts through magnetic repulsion to rapidly open the contacts. A pair of telescoping shield sleeves that have aligned openings through which the moving contact is extended to close with the fixed contact are oppositely driven transversely to piston movement by the arc gases to cut off the arc.