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公开(公告)号:US20050106641A1
公开(公告)日:2005-05-19
申请号:US10981130
申请日:2004-11-03
申请人: Lawrence Kauvar , Remy Cromer , William Harriman
发明人: Lawrence Kauvar , Remy Cromer , William Harriman
IPC分类号: C12N5/08 , G01N20060101 , G01N15/06 , G01N21/64 , G01N27/447 , G01N30/74 , G01N30/88 , G01N33/50 , G01N33/53 , G01N33/543 , G01N33/567 , G01N33/58
CPC分类号: G01N15/0625 , G01N21/6428 , G01N21/6458 , G01N27/44726 , G01N30/74 , G01N30/88 , G01N33/505 , G01N33/5052 , G01N33/54313 , G01N33/585 , G01N2021/6441 , G01N2030/8813 , G01N2030/8827 , Y10T436/112499 , Y10T436/13 , Y10T436/25125 , Y10T436/25375
摘要: New applications for the use of distinguishable particulate labels available in a variety of hues and sized in the submicron range are described. These applications include profiling of cellular components, obtaining secretion patterns, identifying a multiplicity of components in chromatographic or electrophoretic techniques and identification of desired immunoglobulin secreting cells.
摘要翻译: 描述了使用可用于各种色调并且在亚微米范围内尺寸的可区分颗粒标签的新应用。 这些应用包括细胞组分的分析,获得分泌模式,在色谱或电泳技术中鉴定多种组分并鉴定所需的免疫球蛋白分泌细胞。
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公开(公告)号:US20080038755A1
公开(公告)日:2008-02-14
申请号:US11777218
申请日:2007-07-12
CPC分类号: C07K16/00 , G01N33/5005 , G01N33/56966 , G01N33/56972 , G01N33/6842 , G01N33/6845 , G01N33/6854
摘要: A multiplicity of applications of the CellSpot™ assay method are described. Among these applications are extension to integral membrane protein probes, extension to secretion from bacterial cells, identification of antibodies with enhanced affinity, identification of clones with increased secretion levels, and use of massively parallel screening to identify rare efficacious antibodies.
摘要翻译: 描述了CellSpot TM测定方法的多种应用。 在这些应用中,这些应用是扩展到整合膜蛋白探针,从细菌细胞分泌的延伸,增强亲和力的抗体鉴定,鉴定具有增加的分泌水平的克隆,以及使用大规模平行筛选来鉴定罕见的有效抗体。
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