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    Predictive Method for Controlling a Blood Processing System
    1.
    发明申请
    Predictive Method for Controlling a Blood Processing System 有权
    控制血液处理系统的预测方法

    公开(公告)号：US20100025336A1

    公开(公告)日：2010-02-04

    申请号：US12561419

    申请日：2009-09-17

    申请人： Lee F. CARTER ,  Jeremy P. KOLENBRANDER ,  James R. LADTKOW ,  Joseph A. SCIBONA ,  Jeffrey A. STEWARD ,  Chris FLETCHER

    发明人： Lee F. CARTER ,  Jeremy P. KOLENBRANDER ,  James R. LADTKOW ,  Joseph A. SCIBONA ,  Jeffrey A. STEWARD ,  Chris FLETCHER

    IPC分类号： B04B13/00

    CPC分类号： G01N15/042 ,  A61M1/3693 ,  B04B13/00 ,  B04B2013/006 ,  G01N15/05 ,  G01N2015/047

    摘要： The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. The method may include performing first and second measurements of an operating condition; analyzing the first and second measurements using a predictive data analysis algorithm; comparing the predicted operating condition to a desired operating condition; and adjusting at least one setting.

    摘要翻译： 本发明一般涉及监测和控制血液和血液样品的处理，特别是将血液和血液样品分离成其组分的方法。 一方面，本发明涉及用于测量来自密度离心机的分离室的透射光强度，散射光强度或二者的二维分布的光学方法。 该方法可以包括执行操作条件的第一和第二测量; 使用预测数据分析算法分析第一和第二测量; 将预测的操作条件与期望的操作条件进行比较; 并调整至少一个设置。

    Monitoring and Control System for Blood Processing
    3.
    发明申请
    Monitoring and Control System for Blood Processing 有权
    血液处理监控系统

    公开(公告)号：US20080283781A1

    公开(公告)日：2008-11-20

    申请号：US12168192

    申请日：2008-07-07

    申请人： Lee F. CARTER ,  Jeremy P. KOLENBRANDER ,  James R. LADTKOW ,  Joseph A. SCIBONA ,  Jeffrey A. STEWARD ,  Chris FLETCHER

    发明人： Lee F. CARTER ,  Jeremy P. KOLENBRANDER ,  James R. LADTKOW ,  Joseph A. SCIBONA ,  Jeffrey A. STEWARD ,  Chris FLETCHER

    IPC分类号： G01N15/05

    CPC分类号： G01N15/042 ,  A61M1/3693 ,  B04B13/00 ,  B04B2013/006 ,  G01N15/05 ,  G01N2015/047

    摘要： The invention relates to an optical cell for a separation chamber of a density centrifuge blood processing system for separating fluid components comprising an extraction chamber having a first external optical surface for transmitting at least a portion of an incident optical beam; and an extraction port having an axial bore for passing fluid components and a first external optical surface for transmitting at least a portion of the incident optical beam; wherein said first external optical surface of said extraction chamber and said first external optical surface of said extraction port are both positioned within the depth of field of a light collection element.

    摘要翻译： 本发明涉及一种用于分离流体组分的密度离心机血液处理系统的分离室的光学单元，该液体组分包括具有第一外部光学表面的提取室，用于透射入射光束的至少一部分; 以及具有用于通过流体部件的轴向孔的抽出口和用于透射入射光束的至少一部分的第一外部光学表面; 其中所述提取室的所述第一外部光学表面和所述提取端口的所述第一外部光学表面都位于光采集元件的深度范围内。

    System for Blood Separation with Shielded Extraction Port and Optical Control
    4.
    发明申请
    System for Blood Separation with Shielded Extraction Port and Optical Control 有权
    带屏蔽提取端口和光学控制的血液分离系统

    公开(公告)号：US20110143905A1

    公开(公告)日：2011-06-16

    申请号：US12959987

    申请日：2010-12-03

    申请人： Jeremy P. KOLENBRANDER ,  Brian M. HOLMES ,  Thomas J. FELT ,  James R. LADTKOW

    发明人： Jeremy P. KOLENBRANDER ,  Brian M. HOLMES ,  Thomas J. FELT ,  James R. LADTKOW

    IPC分类号： B04B13/00 ,  B04B15/00

    CPC分类号： G01N21/51 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0439 ,  A61M2205/3306 ,  B04B13/00 ,  B04B2013/006 ,  G01N2035/00495 ,  A61M2202/0071

    摘要： A centrifugal blood separation system comprising a rotor, a light source, an optical sensor, a control system, a separation vessel, and an optical cell on the separation vessel. The optical cell has a first extraction port extending radially outwardly into the optical cell, a red blood cell extraction port downstream from the first extraction port and extending into the optical cell beyond the first extraction port; and a dam between said first extraction port and said red blood cell extraction port, having an upper edge and a lower edge, wherein the first extraction port and the red cell extraction port are radially between the upper edge and the lower edge of the dam. Also, a first extraction port having a bore having a first diameter, a lumen having a second diameter smaller than the first diameter, and a frustro-conical passageway coupling the bore to the lumen.

    摘要翻译： 一种离心血液分离系统，包括转子，光源，光学传感器，控制系统，分离容器和分离容器上的光学单元。 所述光学单元具有径向向外延伸到所述光学单元中的第一提取端口，所述第一提取端口下游并延伸到所述光学单元超出所述第一提取端口的红细胞提取端口; 以及位于所述第一提取口和所述红细胞提取口之间的坝，具有上边缘和下边缘，其中所述第一提取口和所述红细胞提取口径向地位于所述坝的上边缘和下边缘之间。 此外，具有第一直径的孔，具有小于第一直径的第二直径的内腔的第一提取端口和将孔连接到内腔的截头圆锥形通道。