公开(公告)号：US06233595B1

公开(公告)日：2001-05-15

申请号：US09075074

申请日：1998-05-08

申请人： Lei Cheng ,  Frank J. Gorishek, IV ,  Yi Liu

发明人： Lei Cheng ,  Frank J. Gorishek, IV ,  Yi Liu

IPC分类号： G06F9302

CPC分类号： G06F7/4876 ,  G06F9/30014

摘要： A method for performing fast multiplication in a microprocessor is disclosed. The method comprises detecting multiplication operations that have a floating point operand and an integer operand, wherein the integer operand is an integer power of two. Once detected, a multiplication operation meeting these criteria may be executed by using an integer adder to sum the integer power and the floating point operand's exponent to from a product exponent. The bias of the integer operand's exponent may also be subtracted. A product mantissa is simply copied from the floating point operand's mantissa. The floating point operand's sign bit may be inverted to form the product's sign bit if the integer operand is negative. Advantageously, the product is generated using integer addition which is faster than floating point multiplication. The method may be implemented in hardware or software.

摘要翻译： 公开了一种在微处理器中执行快速乘法的方法。 该方法包括检测具有浮点操作数和整数操作数的乘法运算，其中整数操作数是2的整数幂。 一旦被检测到，可以通过使用整数加法器来执行满足这些标准的乘法运算，以从乘积指数将整数幂和浮点运算数的指数相加。 也可以减去整数操作数的指数的偏差。 产品尾数简单地从浮点运算符的尾数复制出来。 如果整数操作数为负，则浮点运算符的符号位可能会反转，以形成乘积符号位。 有利地，使用比浮点乘法更快的整数加法来产生乘积。 该方法可以在硬件或软件中实现。

公开(公告)号：US09155744B2

公开(公告)日：2015-10-13

申请号：US11722915

申请日：2006-10-27

申请人： Ming Li ,  Lei Cheng ,  Hong Wei Liu

发明人： Ming Li ,  Lei Cheng ,  Hong Wei Liu

IPC分类号： A61K31/56 ,  A61K31/704 ,  C07C62/32

CPC分类号： A61K31/704 ,  A61K31/192 ,  A61K31/56 ,  A61K35/34 ,  C07C62/32

摘要： A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.

摘要翻译： 用于再生心肌细胞治疗或修复由缺血性疾病引起的心肌损伤或损伤的药物组合物和方法。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。 活性成分化合物能够（a）增加肌原性前体细胞的活力，使所述前体细胞能够通过绝对缺血期生存; （b）在所述受伤的肌肉位于的所述心脏区域中重建损伤的血液供应网络; 和（c）提高所述前体细胞向下心肌的心肌分化效率，所述步骤同时进行或以任何特定的顺序进行。

公开(公告)号：US07555301B2

公开(公告)日：2009-06-30

申请号：US11507827

申请日：2006-08-21

申请人： Efstratios Skafidas ,  Ben Jones ,  John (Jack) Morton ,  Mike Gibson ,  Neil Patrick Kelly ,  Nestor Fesas ,  Mark William Benson ,  Richard John Rusnak ,  James Glick ,  Duy Khuong Do ,  Douglas A. Mammosser ,  Lei Cheng ,  Kevin Sean Broe ,  Natarajan Ekambaram

发明人： Efstratios Skafidas ,  Ben Jones ,  John (Jack) Morton ,  Mike Gibson ,  Neil Patrick Kelly ,  Nestor Fesas ,  Mark William Benson ,  Richard John Rusnak ,  James Glick ,  Duy Khuong Do ,  Douglas A. Mammosser ,  Lei Cheng ,  Kevin Sean Broe ,  Natarajan Ekambaram

IPC分类号： H04Q7/20

CPC分类号： H04W16/28 ,  H01Q1/246 ,  H01Q25/002 ,  H04B7/0491 ,  H04W16/14 ,  H04W16/24 ,  H04W24/00 ,  H04W72/04 ,  H04W72/082

摘要： A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment. In one embodiment, a mode of operation is selected from a plurality of modes of operation, enabling a wireless communications transmitter to be dynamically configured to reach a wireless communications devices at a greater distance from the transmitter without increased interference between communications channels (“range mode”) or to provide wireless communications to a greater number of wireless communications devices within a relatively closer distance to the wireless transmitter (“capacity mode”) or to provide wireless communications using a single channel to provide wireless communications at a relatively greatest distance from the transmitter (“super range mode”).

摘要翻译： 多址无线通信架构提供与位于被称为“扇区”的通信设备周围的空间区域的不同部分中的无线设备的选择性同时通信。 在一个实施例中，用于增加无线通信环境中的吞吐量和覆盖范围中的一个或多个的信道分配技术。 在一个实施例中，从多种操作模式中选择操作模式，使得无线通信发射机能够被动态配置为在距离发射机更远的距离处到达无线通信设备，而不增加通信信道之间的干扰（“范围模式 “）或者在与无线发射机相对较近的距离内向更多数量的无线通信设备提供无线通信（”容量模式“），或者使用单个信道来提供无线通信，以在距离无线发射机相对最远的距离处提供无线通信 发射机（“超级范围模式”）。

公开(公告)号：US20090022827A1

公开(公告)日：2009-01-22

申请号：US12176441

申请日：2008-07-21

申请人： Ming Li ,  Lei Cheng

发明人： Ming Li ,  Lei Cheng

IPC分类号： A61K36/73 ,  A61P35/04

CPC分类号： A61K36/73

摘要： A pharmaceutical composition including an extract from Geum japonicum and a method of treating cancer using the extract. In vitro and in vivo experimental data demonstrated that the extract can induce selectively apoptosis of cancer cells and kill the cancer cells without affect normal cells.

摘要翻译： 一种药用组合物，其特征在于，包括天麻提取物和使用所述提取物治疗癌症的方法。 体外和体内实验数据表明，提取物可以诱导癌细胞的选择性凋亡，并杀死癌细胞而不影响正常细胞。

公开(公告)号：US20090028959A1

公开(公告)日：2009-01-29

申请号：US11722915

申请日：2006-10-27

申请人： Ming Li ,  Lei Cheng ,  Wei Liu Hong

发明人： Ming Li ,  Lei Cheng ,  Wei Liu Hong

IPC分类号： A61K35/12 ,  A61K31/19 ,  A61K31/704 ,  A61P9/10

CPC分类号： A61K31/704 ,  A61K31/192 ,  A61K31/56 ,  A61K35/34 ,  C07C62/32

摘要： A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.

摘要翻译： 用于再生心肌细胞治疗或修复由缺血性疾病引起的心肌损伤或损伤的药物组合物和方法。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。 活性成分化合物能够（a）增加肌原性前体细胞的活力，使所述前体细胞能够通过绝对缺血期生存; （b）在所述受伤的肌肉位于的所述心脏区域中重建损伤的血液供应网络; 和（c）提高所述前体细胞向下心肌的心肌分化效率，所述步骤同时进行或以任何特定的顺序进行。

公开(公告)号：US20120252744A1

公开(公告)日：2012-10-04

申请号：US13517600

申请日：2012-06-14

申请人： Ming Li ,  Lei Cheng ,  Hong Wei Liu

发明人： Ming Li ,  Lei Cheng ,  Hong Wei Liu

IPC分类号： A61K31/7034 ,  A61P9/10

CPC分类号： A61K31/7034 ,  A61K9/0019 ,  A61K9/0053

摘要： A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (I).

摘要翻译： 一种药物组合物和通过生长新的血管来治疗缺血性心脏病的方法，所述新血管向整个梗塞区域的梗死心脏组织供氧和营养，并用于预防缺血事件中的心肌细胞凋亡。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。

公开(公告)号：US20120177759A1

公开(公告)日：2012-07-12

申请号：US13377501

申请日：2010-06-11

申请人： Ming Li ,  Lei Cheng

发明人： Ming Li ,  Lei Cheng

IPC分类号： A61K36/73 ,  A61P27/02 ,  A61P17/02 ,  A61P3/10

CPC分类号： A61K36/00 ,  A61K31/56 ,  A61K31/565 ,  A61K31/7028 ,  A61K31/7032 ,  A61K31/7034 ,  A61K36/23 ,  A61K36/73 ,  A61K2300/00 ,  Y02A50/411

摘要： Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum and methods for increasing longevity and survival potency or for preventing or treating various medical conditions, including diabetes, inflammation, wound healing, bed sores, and ocular disorders. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments

摘要翻译： 本文公开了植物天麻的化合物，提取物和活性级分以及用于增加寿命和存活效力或用于预防或治疗各种医学病症（包括糖尿病，炎症，伤口愈合，褥疮和眼部疾病）的方法。 本文提供的化合物可以配制成在所公开的方法中有用的药物组合物和药物。 还提供了化合物和提取物在制备药物制剂和药物中的用途

公开(公告)号：US20080124388A1

公开(公告)日：2008-05-29

申请号：US11722911

申请日：2006-10-27

申请人： Ming Li ,  Lei Cheng ,  Hong Wei Liu

发明人： Ming Li ,  Lei Cheng ,  Hong Wei Liu

IPC分类号： A61K31/7024 ,  A61K9/48 ,  A61K9/20

CPC分类号： A61K31/704 ,  A61K31/192 ,  A61K31/56 ,  A61K35/34 ,  C07C62/32

摘要： A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (I).

摘要翻译： 一种药物组合物和通过生长新的血管来治疗缺血性心脏病的方法，所述新血管向整个梗塞区域的梗死心脏组织供氧和营养，并用于预防缺血事件中的心肌细胞凋亡。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。

公开(公告)号：US20060281412A1

公开(公告)日：2006-12-14

申请号：US11507827

申请日：2006-08-21

申请人： Efstratios Skafidas ,  Ben Jones ,  John Morton ,  Mike Gibson ,  Neil Kelly ,  Nestor Fesas ,  Mark Benson ,  Richard Rusnak ,  James Glick ,  Duy Do ,  Douglas Mammoser ,  Lei Cheng ,  Kevin Broe ,  Natarajan Ekambaram

发明人： Efstratios Skafidas ,  Ben Jones ,  John Morton ,  Mike Gibson ,  Neil Kelly ,  Nestor Fesas ,  Mark Benson ,  Richard Rusnak ,  James Glick ,  Duy Do ,  Douglas Mammoser ,  Lei Cheng ,  Kevin Broe ,  Natarajan Ekambaram

IPC分类号： H04B1/00

CPC分类号： H04W16/28 ,  H01Q1/246 ,  H01Q25/002 ,  H04B7/0491 ,  H04W16/14 ,  H04W16/24 ,  H04W24/00 ,  H04W72/04 ,  H04W72/082

摘要： A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment. In one embodiment, a mode of operation is selected from a plurality of modes of operation, enabling a wireless communications transmitter to be dynamically configured to reach a wireless communications devices at a greater distance from the transmitter without increased interference between communications channels (“range mode”) or to provide wireless communications to a greater number of wireless communications devices within a relatively closer distance to the wireless transmitter (“capacity mode”) or to provide wireless communications using a single channel to provide wireless communications at a relatively greatest distance from the transmitter (“super range mode”).

公开(公告)号：US07136655B2

公开(公告)日：2006-11-14

申请号：US10870199

申请日：2004-06-16

申请人： Efstratios Skafidas ,  Ben Jones ,  John “Jack” Morton ,  Mike Gibson ,  Neil Patrick Kelly ,  Nestor Fesas ,  Mark William Benson ,  Richard John Rusnak ,  James Glick ,  Duy Khuong Do ,  Douglas A. Mammoser ,  Lei Cheng ,  Kevin Sean Broe ,  Natarajan Ekambaram

发明人： Efstratios Skafidas ,  Ben Jones ,  John “Jack” Morton ,  Mike Gibson ,  Neil Patrick Kelly ,  Nestor Fesas ,  Mark William Benson ,  Richard John Rusnak ,  James Glick ,  Duy Khuong Do ,  Douglas A. Mammoser ,  Lei Cheng ,  Kevin Sean Broe ,  Natarajan Ekambaram

IPC分类号： H04Q7/20

CPC分类号： H04W16/28 ,  H01Q1/246 ,  H01Q25/002 ,  H04B7/0491 ,  H04W16/14 ,  H04W16/24 ,  H04W24/00 ,  H04W72/04 ,  H04W72/082

摘要： A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment. In one embodiment, a mode of operation is selected from a plurality of modes of operation, enabling a wireless communications transmitter to be dynamically configured to reach a wireless communications devices at a greater distance from the transmitter without increased interference between communications channels (“range mode”) or to provide wireless communications to a greater number of wireless communications devices within a relatively closer distance to the wireless transmitter (“capacity mode”) or to provide wireless communications using a single channel to provide wireless communications at a relatively greatest distance from the transmitter (“super range mode”).