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1.发明授权Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries 有权用于再生肌纤维治疗肌肉损伤的药物组合物和方法公开(公告)号：US09155744B2
公开(公告)日：2015-10-13
申请号：US11722915
申请日：2006-10-27
申请人： Ming Li , Lei Cheng , Hong Wei Liu
发明人： Ming Li , Lei Cheng , Hong Wei Liu
IPC分类号： A61K31/56 , A61K31/704 , C07C62/32
CPC分类号： A61K31/704 , A61K31/192 , A61K31/56 , A61K35/34 , C07C62/32
摘要： A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.
摘要翻译： 用于再生心肌细胞治疗或修复由缺血性疾病引起的心肌损伤或损伤的药物组合物和方法。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。 活性成分化合物能够（a）增加肌原性前体细胞的活力，使所述前体细胞能够通过绝对缺血期生存; （b）在所述受伤的肌肉位于的所述心脏区域中重建损伤的血液供应网络; 和（c）提高所述前体细胞向下心肌的心肌分化效率，所述步骤同时进行或以任何特定的顺序进行。
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2.发明申请AGENT AND METHOD FOR ELIMINATING MALIGNANCE OF CANCER CELLS WITHOUT HARMFUL EFFECT TO NORMAL CELLS 审中-公开用于消除癌细胞恶性病变的代理和方法，对正常细胞没有有害的作用公开(公告)号：US20090022827A1
公开(公告)日：2009-01-22
申请号：US12176441
申请日：2008-07-21
CPC分类号： A61K36/73
摘要： A pharmaceutical composition including an extract from Geum japonicum and a method of treating cancer using the extract. In vitro and in vivo experimental data demonstrated that the extract can induce selectively apoptosis of cancer cells and kill the cancer cells without affect normal cells.
摘要翻译： 一种药用组合物，其特征在于，包括天麻提取物和使用所述提取物治疗癌症的方法。 体外和体内实验数据表明，提取物可以诱导癌细胞的选择性凋亡，并杀死癌细胞而不影响正常细胞。
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3.发明申请PHARMACEUTICAL COMPOSITION AND METHOD FOR REGENERATING MYOFIBERS IN THE TREATMENT OF MUSCLE INJURIES 有权药物组合物和方法用于在治疗肌肉损伤时再生肌孕酮公开(公告)号：US20090028959A1
公开(公告)日：2009-01-29
申请号：US11722915
申请日：2006-10-27
申请人： Ming Li , Lei Cheng , Wei Liu Hong
发明人： Ming Li , Lei Cheng , Wei Liu Hong
IPC分类号： A61K35/12 , A61K31/19 , A61K31/704 , A61P9/10
CPC分类号： A61K31/704 , A61K31/192 , A61K31/56 , A61K35/34 , C07C62/32
摘要： A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.
摘要翻译： 用于再生心肌细胞治疗或修复由缺血性疾病引起的心肌损伤或损伤的药物组合物和方法。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。 活性成分化合物能够（a）增加肌原性前体细胞的活力，使所述前体细胞能够通过绝对缺血期生存; （b）在所述受伤的肌肉位于的所述心脏区域中重建损伤的血液供应网络; 和（c）提高所述前体细胞向下心肌的心肌分化效率，所述步骤同时进行或以任何特定的顺序进行。
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4.发明申请Pharmaceutical Composition and Method for Neoangiogenesis/Revascularization Useful in Treating Ischemic Heart Disease 审中-公开用于治疗缺血性心脏病的新血管生成/血运重建的药物组合物和方法公开(公告)号：US20120252744A1
公开(公告)日：2012-10-04
申请号：US13517600
申请日：2012-06-14
申请人： Ming Li , Lei Cheng , Hong Wei Liu
发明人： Ming Li , Lei Cheng , Hong Wei Liu
IPC分类号： A61K31/7034 , A61P9/10
CPC分类号： A61K31/7034 , A61K9/0019 , A61K9/0053
摘要： A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (I).
摘要翻译： 一种药物组合物和通过生长新的血管来治疗缺血性心脏病的方法，所述新血管向整个梗塞区域的梗死心脏组织供氧和营养，并用于预防缺血事件中的心肌细胞凋亡。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。
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公开(公告)号：US20120177759A1
公开(公告)日：2012-07-12
申请号：US13377501
申请日：2010-06-11
CPC分类号： A61K36/00 , A61K31/56 , A61K31/565 , A61K31/7028 , A61K31/7032 , A61K31/7034 , A61K36/23 , A61K36/73 , A61K2300/00 , Y02A50/411
摘要： Disclosed herein are compounds, extracts, and active fractions of the plant Geum japonicum and methods for increasing longevity and survival potency or for preventing or treating various medical conditions, including diabetes, inflammation, wound healing, bed sores, and ocular disorders. The compounds provided herein can be formulated into pharmaceutical compositions and medicaments that are useful in the disclosed methods. Also provided are the use of the compounds and extracts in preparing pharmaceutical formulations and medicaments
摘要翻译： 本文公开了植物天麻的化合物，提取物和活性级分以及用于增加寿命和存活效力或用于预防或治疗各种医学病症（包括糖尿病，炎症，伤口愈合，褥疮和眼部疾病）的方法。 本文提供的化合物可以配制成在所公开的方法中有用的药物组合物和药物。 还提供了化合物和提取物在制备药物制剂和药物中的用途
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6.发明申请Pharmaceutical Composition And Method For Neoangiogenesis/Revascularization Useful In Treating Ischemic Heart Diseases 审中-公开用于治疗缺血性心脏病的新血管生成/血运重建的药物组合物和方法公开(公告)号：US20080124388A1
公开(公告)日：2008-05-29
申请号：US11722911
申请日：2006-10-27
申请人： Ming Li , Lei Cheng , Hong Wei Liu
发明人： Ming Li , Lei Cheng , Hong Wei Liu
IPC分类号： A61K31/7024 , A61K9/48 , A61K9/20
CPC分类号： A61K31/704 , A61K31/192 , A61K31/56 , A61K35/34 , C07C62/32
摘要： A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (I).
摘要翻译： 一种药物组合物和通过生长新的血管来治疗缺血性心脏病的方法，所述新血管向整个梗塞区域的梗死心脏组织供氧和营养，并用于预防缺血事件中的心肌细胞凋亡。 药物组合物含有具有式（I）的骨架结构的活性成分化合物。
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公开(公告)号：US10298946B2
公开(公告)日：2019-05-21
申请号：US14355785
申请日：2012-07-24
IPC分类号： H04N19/46 , H04N19/70 , H04N19/174
摘要： Provided is a method for encoding parameter sets at slice level. The method includes: when there are one or more parameter sets, in which the coding tool parameters are identical to the coding tool parameters of a part of coding tools used for the current slice, in the existing parameter sets, encoding the identifiers of parameter sets into bit-stream of the current slice, wherein a parameter set contains common information of the coding tools used in the process of encoding/decoding slice(s). Correspondingly, also provided is a method for decoding parameter sets at slice level and a device for encoding and decoding parameter sets at slice level, which can make full use of the encoded parameter set information when the slice header refers to a plurality of parameter sets, implement flexible configuration of the coding tools used in the process of encoding/decoding slice(s) and reduce information redundancy.
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公开(公告)号：US10012224B2
公开(公告)日：2018-07-03
申请号：US13807399
申请日：2010-10-11
申请人： Ming Li , Zhengzhong Li
发明人： Ming Li , Zhengzhong Li
IPC分类号： F02B75/06 , F04B39/00 , F16H21/22 , F02B75/32 , F16F15/28 , F16H21/36 , F01B9/06 , F04B53/00
CPC分类号： F04B39/0094 , F01B9/06 , F02B75/32 , F04B9/045 , F04B27/053 , F04B53/006 , F16F15/283 , F16H21/22 , F16H21/36 , Y10T74/18208
摘要： A crank circular slider mechanism includes a crankshaft having at least one crank pin; at least one circular slider with an eccentric hole which fits over the crank pin; at least one reciprocating element with a circular slider-receiving hole, which receives the circular slider in a rotatable manner; and at least one dynamic balance rotary block with an eccentric hole that fits over the crank pin. The dynamic balance rotary block and the adjacent circular slider are fixed together. By means of proper selection of a mounting place and a mass of the dynamic balance rotary block, the mechanism can convert reciprocating inertia of the reciprocating element into rotation inertia so as to obtain a balancing effect. An internal combustion engine and a compressor may be equipped with the crank circular slider mechanism.
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公开(公告)号：US10000844B2
公开(公告)日：2018-06-19
申请号：US13698884
申请日：2011-08-30
申请人： Wei Kong , Zijing Lin , Ming Li , Bin Xie , Haiqian Wang , Yousong Jiang , Ekishu Nagae
发明人： Wei Kong , Zijing Lin , Ming Li , Bin Xie , Haiqian Wang , Yousong Jiang , Ekishu Nagae
CPC分类号： C23C14/351 , C23C14/35 , H01F7/081 , H01J25/50 , H01J37/3405 , H01J37/3452 , H01J37/3461
摘要： A magnetic field generator arranged behind a target and for generating a magnetic field on a front surface of the target based on magnetic force lines can include a ring-shaped outer magnetic body having a pole axis in a parallel direction (X-direction) with respect to the target surface, a center magnetic body arranged on an inner side of the outer magnetic body and having a pole axis in a parallel direction (X-direction) with the direction of the pole axis of the outer magnetic body, a yoke plate for supporting the outer magnetic body and the center magnetic body from behind, and a magnetic permeable plate for changing a magnetic field distribution of the front surface of the target. The magnetic permeable plate is arranged so as to be supported by the yoke plate from behind.
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