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公开(公告)号：US5145840A
公开(公告)日：1992-09-08
申请号：US679236
申请日：1991-04-02
摘要： A method of treating idiopathic thrombocytopaenia purpura with 2',3'-dideoxy-3'-azidonucleosides, in particular 3'-azido-3'-deoxythymidine, is disclosed.
摘要翻译： 公开了用2'，3'-二脱氧-3'-叠氮核苷特别是3'-叠氮-3'-脱氧胸苷治疗特发性血小板减少症紫癜的方法。
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公开(公告)号：US5086044A
公开(公告)日：1992-02-04
申请号：US510590
申请日：1990-04-18
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： C07H19/06 , C07H19/16 , Y10S514/934
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose. Additionally, there is disclosed the treatment of Kaposi's sarcoma with 3'-azido-3'-deoxythymidine (AZT) and the synergistic activity in the treatment of humans infected with HTLV-III of AZT and interferon as well as AZT and acyclovir.
摘要翻译： 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上可接受的碱性盐来公开用艾滋病病毒携带或感染艾滋病病毒或具有抗艾滋病病毒抗体的艾滋病或人类的治疗。 还公开了3'-叠氮基-3'-脱氧胸苷的5'-单，二和三磷酸或其药学上可接受的碱性盐用于相同目的。 另外，公开了用3'-叠氮基-3'-脱氧胸苷（AZT）处理卡波西氏肉瘤的方法，以及AZT和干扰素以及AZT和阿昔洛韦感染HTLV-III的人的治疗中的协同作用。
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公开(公告)号：US4780453A
公开(公告)日：1988-10-25
申请号：US945234
申请日：1986-12-23
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： A61K31/70 , A61K31/7072 , A61K38/212 , C07H19/06 , C07H19/10 , Y10S424/15 , Y10S514/934 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/966
摘要： Treatment of cats carrying or infected with the Feline Leukemia virus or having antibodies to the Feline leukemia virus is disclosed using the compound 3'-azido''-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
摘要翻译： 使用化合物3'-叠氮基 - 脱氧胸苷或其药学上可接受的碱性盐来公开携带或感染猫白血病病毒或具有针对猫科白血病病毒抗体的猫的处理。 还公开了3'-叠氮基-3'-脱氧胸苷的5'-单，二和三磷酸或其药学上可接受的碱性盐用于相同目的。
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公开(公告)号：US4847244A
公开(公告)日：1989-07-11
申请号：US110947
申请日：1987-10-20
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
摘要： Treatments of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
摘要翻译： 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上可接受的碱式盐来公开对携带或感染艾滋病病毒或具有AIDS病毒抗体的AIDS或人的治疗。 还公开了3'-叠氮基-3'-脱氧胸苷的5'-单，二和三磷酸或其药学上可接受的碱性盐用于相同目的。
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公开(公告)号：US4828838A
公开(公告)日：1989-05-09
申请号：US111208
申请日：1987-10-21
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： A61K31/70 , A61K31/7072 , A61K38/212 , C07H19/06 , C07H19/10 , Y10S424/15 , Y10S514/934 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/966
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
摘要翻译： 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上可接受的碱性盐来公开用艾滋病病毒携带或感染艾滋病病毒或具有抗艾滋病病毒抗体的AIDS或人的治疗。 还公开了3'-叠氮基-3'-脱氧胸苷的5'-单，二和三磷酸或其药学上可接受的碱性盐用于相同目的。
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公开(公告)号：US4818750A
公开(公告)日：1989-04-04
申请号：US110968
申请日：1987-10-20
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-dexoythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
摘要翻译： 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上的碱式盐来公开用艾滋病病毒携带或感染艾滋病病毒或具有艾滋病病毒抗体的AIDS或人的治疗。 还公开了3'-叠氮基-3'-脱甲基胸苷的5'-单，二和三磷酸或其药学上可接受的碱性盐用于相同目的。
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公开(公告)号：US4818538A
公开(公告)日：1989-04-04
申请号：US111205
申请日：1987-10-21
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： A61K31/70 , A61K31/7072 , A61K38/212 , C07H19/06 , C07H19/10 , Y10S424/15 , Y10S514/934 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/966
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5.dbd.-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
摘要翻译： 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上可接受的碱性盐来公开用艾滋病病毒携带或感染艾滋病病毒或具有抗艾滋病病毒抗体的AIDS或人的治疗。 还公开了用于相同目的的3'-叠氮基-3'-脱氧胸苷的5' - 单 - ，二 - 和三磷酸或其药学上可接受的碱性盐的用途。
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公开(公告)号：US4724232A
公开(公告)日：1988-02-09
申请号：US776899
申请日：1985-09-17
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： A61K31/70 , A61K31/7072 , A61K38/212 , C07H19/06 , C07H19/10 , Y10S424/15 , Y10S514/934 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/966
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
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公开(公告)号：US4874609A
公开(公告)日：1989-10-17
申请号：US153258
申请日：1988-02-08
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： A61K31/70 , A61K31/7072 , A61K38/212 , C07H19/06 , C07H19/10 , Y10S424/15 , Y10S514/934 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/966
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
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公开(公告)号：US4857511A
公开(公告)日：1989-08-15
申请号：US152977
申请日：1988-02-08
申请人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
发明人： Janet L. Rideout , David W. Barry , Sandra N. Lehrman , Martha H. St. Clair , Phillip A. Furman
CPC分类号： A61K31/70 , C07H19/06 , C07H19/10 , C07H19/16 , Y10S514/885 , Y10S514/934
摘要： Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
摘要翻译： 使用化合物3'-叠氮基-3'-脱氧胸苷或其药学上可接受的碱性盐来公开用艾滋病病毒携带或感染艾滋病病毒或具有抗艾滋病病毒抗体的AIDS或人的治疗。 还公开了3'-叠氮基-3'-脱氧胸苷的5'-单，二和三磷酸或其药学上可接受的碱性盐用于相同目的。
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