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1.发明授权Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them 有权二氢吲哚酮化合物，其制备方法和含有它们的药物组合物公开(公告)号：US08653073B2
公开(公告)日：2014-02-18
申请号：US13772984
申请日：2013-02-21
发明人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Imre Fejes , Michael Burnbridge , John Hickman , Alain Pierre
IPC分类号： A61K31/5377 , A61K31/445 , A61K31/404
CPC分类号： C07D417/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14
摘要： Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
摘要翻译： 式（I）化合物：其中：m和n表示1或2，A表示吡咯基，X表示C（O），S（O）或SO 2基团，R 1和R 2表示烷基， 与它们携带的氮原子一起形成杂环基，R3和R4与携带它们的原子一起形成杂环基，R 5表示氢原子或烷基，R 6表示氢原子或卤素原子。 含有该药物的药物可用于治疗癌症。
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2.发明申请DIHYDROINDOLONE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 有权二氢吲哚酮化合物，其制备方法和含有它们的药物组合物公开(公告)号：US20130331380A1
公开(公告)日：2013-12-12
申请号：US13772984
申请日：2013-02-21
发明人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Imre Fejes , Michael Burbridge , John Hickman , Alain Pierre
IPC分类号： C07D417/14 , C07D403/14 , C07D413/14
CPC分类号： C07D417/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14
摘要： Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
摘要翻译： 式（I）化合物：其中：m和n表示1或2，A表示吡咯基，X表示C（O），S（O）或SO 2基团，R 1和R 2表示烷基， 与它们携带的氮原子一起形成杂环基，R3和R4与携带它们的原子一起形成杂环基，R 5表示氢原子或烷基，R 6表示氢原子或卤素原子。 含有该药物的药物可用于治疗癌症。
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3.发明授权Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them 有权二氢吲哚酮化合物，其制备方法和含有它们的药物组合物公开(公告)号：US08541412B2
公开(公告)日：2013-09-24
申请号：US13373016
申请日：2011-11-02
IPC分类号： A61K31/5377 , A61K31/445 , A61K31/404
CPC分类号： C07D417/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14
摘要： Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
摘要翻译： 式（I）化合物：其中：m和n表示1或2，A表示吡咯基，X表示C（O），S（O）或SO 2基团，R 1和R 2表示烷基， 与它们携带的氮原子一起形成杂环基，R3和R4与携带它们的原子一起形成杂环基，R 5表示氢原子或烷基，R 6表示氢原子或卤素原子。 含有该药物的药物可用于治疗癌症。
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4.发明授权Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them 有权二氢吲哚酮化合物，其制备方法和含有它们的药物组合物公开(公告)号：US08133889B2
公开(公告)日：2012-03-13
申请号：US12806045
申请日：2010-08-04
申请人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Vincent Lacoste, legal representative , Pauline Lacoste, legal representative , Imre Fejes , Michael Burbridge , John Hickman , Alain Pierre
发明人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Imre Fejes , Michael Burbridge , John Hickman , Alain Pierre
IPC分类号： A61K31/5377 , A61K31/422 , A61K31/496 , A61K31/454 , C07D413/14 , A61P35/00
CPC分类号： C07D417/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14
摘要： Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
摘要翻译： 式（I）化合物：其中：m和n表示1或2，A表示吡咯基，X表示C（O），S（O）或SO 2基团，R 1和R 2表示烷基， 与它们携带的氮原子一起形成杂环基，R3和R4与携带它们的原子一起形成杂环基，R 5表示氢原子或烷基，R 6表示氢原子或卤素原子。 含有该药物的药物可用于治疗癌症。
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公开(公告)号：US20120046287A1
公开(公告)日：2012-02-23
申请号：US13373016
申请日：2011-11-02
申请人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Vincent Lacoste , Pauline Lacoste , Imre Fejes
发明人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Vincent Lacoste , Pauline Lacoste , Imre Fejes
IPC分类号： A61K31/5377 , A61K31/445 , A61P35/04 , A61K31/404
CPC分类号： C07D417/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14
摘要： Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
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6.发明申请Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them 有权二氢吲哚酮化合物，其制备方法和含有它们的药物组合物公开(公告)号：US20110034460A1
公开(公告)日：2011-02-10
申请号：US12806045
申请日：2010-08-04
申请人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Vincent Lacoste , Pauline Lacoste , Imre Fejes , Michael Burbridge , John Hickman , Alain Pierre
发明人： Jean-Claude Ortuno , Alexis Cordi , Jean-Michel Lacoste , Vincent Lacoste , Pauline Lacoste , Imre Fejes , Michael Burbridge , John Hickman , Alain Pierre
IPC分类号： A61K31/5377 , C07D413/14 , A61K31/422 , A61K31/496 , A61K31/454 , A61P35/00
CPC分类号： C07D417/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14
摘要： Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
摘要翻译： 式（I）化合物：其中：m和n表示1或2，A表示吡咯基，X表示C（O），S（O）或SO 2基团，R 1和R 2表示烷基， 与它们携带的氮原子一起形成杂环基，R3和R4与携带它们的原子一起形成杂环基，R 5表示氢原子或烷基，R 6表示氢原子或卤素原子。 含有该药物的药物可用于治疗癌症。
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