公开(公告)号：US20160010146A1

公开(公告)日：2016-01-14

申请号：US14809418

申请日：2015-07-27

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Robert GREEN ,  Dennis Wang ,  Julio Mulero ,  Robert Lagace

IPC: C12Q1/68

CPC classification number: C12Q1/6827 ,  C12Q1/686 ,  C12Q1/6888 ,  C12Q2537/143 ,  C12Q2600/156

Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.

Abstract translation: 公开了使用高度复杂的序列位点SE33（ACTBP2）在单次和多重PCR反应中进行人类鉴定的引物组合物，方法和试剂盒。 另外，所公开的是在SE33基因座内的三种新发现的单核苷酸多态性（SNP），其可以导致视为移动性偏移或等位基因缺失的不一致。 还公开了可用于人类鉴定的试剂盒。

公开(公告)号：US20220205023A1

公开(公告)日：2022-06-30

申请号：US17585161

申请日：2022-01-26

Applicant: Life Technologies Corporation

Inventor： Robert GREEN ,  Dennis WANG ,  Julio MULERO ,  Robert LAGACE

IPC: C12Q1/6827 ,  C12Q1/6888

Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.