公开(公告)号：US20040022475A1

公开(公告)日：2004-02-05

申请号：US10417976

申请日：2003-04-17

申请人： Luna Innovations, Inc.

发明人： Charles D. Pennington

IPC分类号： G02B006/00

CPC分类号： G01N21/774 ,  B82Y20/00 ,  G01N21/553 ,  G01N2021/7716 ,  G02B6/02033 ,  G02B6/02095 ,  G02B6/1221 ,  G02B6/1226

摘要： A biosensor having enhanced sensitivity to physical or chemical parameters comprises a waveguide and a coating disposed on the waveguide. The coating has a refractive index that enhances the sensitivity of the biosensor to physical or chemical parameters. In a preferred embodiment, the coating comprises at least one dendrimer disposed on the waveguide, wherein the coating has a refractive index ranging from about 1.0 to about 1.5. A method for fabrication of the biosensor is also provided.

摘要翻译： 具有对物理或化学参数的敏感性增强的生物传感器包括布置在波导上的波导和涂层。 涂层具有提高生物传感器对物理或化学参数的敏感性的折射率。 在优选的实施方案中，涂层包含设置在波导上的至少一个树状聚合物，其中涂层的折射率范围为约1.0至约1.5。 还提供了生物传感器的制造方法。

公开(公告)号：US20040218847A1

公开(公告)日：2004-11-04

申请号：US10805081

申请日：2004-03-19

申请人： Luna Innovations, Inc.

发明人： Joshua P. Averett ,  Jennifer L. Elster ,  Mark E. Jones ,  Charles D. Pennington ,  Roger L. VanTassell

IPC分类号： G02B006/00

CPC分类号： G01D5/35383 ,  G01D5/35303 ,  G01N33/54373

摘要： A fiber-optic method for making simultaneous multiple parameter measurements employs an optical fiber sensor having at least one long period grating disposed therein. An excitation is created in the optical fiber sensor wherein a plurality of evanescent field sensing depths result. At least two long period grating signatures are created. When the optical fiber sensor is exposed to at least one material, changes in the material are identified by simultaneously measuring and comparing shifts in each long period grating signature; correlating the shifts to changes in the material; and solving a series of equations that compare changes in the coupling wavelength for a specific loss band. A reactive coating may be applied to the optical fiber sensor proximate to the long period grating such that changes in the reactive coating as it reacts with the material may also be monitored.

摘要翻译： 用于进行同时多参数测量的光纤方法使用具有设置在其中的至少一个长周期光栅的光纤传感器。 在光纤传感器中产生激发，其中产生多个消逝场感测深度。 创建至少两个长周期光栅签名。 当光纤传感器暴露于至少一种材料时，通过同时测量和比较每个长周期光栅标记中的位移来识别材料的变化; 将转移与材料变化相关联; 并求解一系列方程，比较特定损耗带的耦合波长变化。 可以将反应性涂层施加到靠近长周期光栅的光纤传感器，使得当反应性涂层与材料反应时的变化也可以被监测。