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公开(公告)号：US07252651B2
公开(公告)日：2007-08-07
申请号：US10337413
申请日：2003-01-07
IPC分类号： A61M5/32
CPC分类号： A61M5/3234 , A61M5/2033 , A61M5/2429 , A61M5/46 , A61M5/502 , A61M2005/2013 , A61M2005/3247 , A61M2037/0023
摘要： An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the locking mechanism prevents the needle from being placed in the injection position.
摘要翻译： 提供注射装置。 该装置包括具有限定第一开口的第一端的壳体。 柱塞被容纳在壳体的第一开口内以在第一和第二位置之间移动。 盒体设置在壳体中，并且具有用作药物的储存器的内部。 输送针设置在壳体内并且经由可中断流体通道与储存器流体连通。 锁定机构设置在壳体中。 在柱塞的第一位置，输送针由柱塞封闭，并且在柱塞的第二位置中，输送针被放置在注射位置，并且柱塞启动锁定机构，由此当柱塞返回到第一位置时，锁定 机构防止针头置于注射位置。
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公开(公告)号：US20120184914A1
公开(公告)日：2012-07-19
申请号：US13429555
申请日：2012-03-26
CPC分类号： A61M5/3234 , A61M5/2033 , A61M5/2429 , A61M5/46 , A61M5/502 , A61M2005/2013 , A61M2005/3247 , A61M2037/0023
摘要： An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the .locking mechanism prevents the needle from being placed in the injection position.
摘要翻译： 提供注射装置。 该装置包括具有限定第一开口的第一端的壳体。 柱塞被容纳在壳体的第一开口内以在第一和第二位置之间移动。 盒体设置在壳体中，并且具有用作药物的储存器的内部。 输送针设置在壳体内并且经由可中断流体通道与储存器流体连通。 锁定机构设置在壳体中。 在柱塞的第一位置，输送针由柱塞封闭，并且在柱塞的第二位置中，输送针位于注射位置，并且柱塞启动锁定机构，由此当柱塞返回到第一位置时。 锁定机构防止针头被置于注射位置。
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公开(公告)号：US07905866B2
公开(公告)日：2011-03-15
申请号：US11769214
申请日：2007-06-27
CPC分类号： A61M5/3234 , A61M5/2033 , A61M5/2429 , A61M5/46 , A61M5/502 , A61M2005/2013 , A61M2005/3247 , A61M2037/0023
摘要： An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the locking mechanism prevents the needle from being placed in the injection position.
摘要翻译： 提供注射装置。 该装置包括具有限定第一开口的第一端的壳体。 柱塞被容纳在壳体的第一开口内以在第一和第二位置之间移动。 盒体设置在壳体中，并且具有用作药物的储存器的内部。 输送针设置在壳体内并且经由可中断流体通道与储存器流体连通。 锁定机构设置在壳体中。 在柱塞的第一位置，输送针由柱塞封闭，并且在柱塞的第二位置中，输送针被放置在注射位置，并且柱塞启动锁定机构，由此当柱塞返回到第一位置时，锁定 机构防止针头置于注射位置。
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公开(公告)号：US08603040B2
公开(公告)日：2013-12-10
申请号：US13429555
申请日：2012-03-26
CPC分类号： A61M5/3234 , A61M5/2033 , A61M5/2429 , A61M5/46 , A61M5/502 , A61M2005/2013 , A61M2005/3247 , A61M2037/0023
摘要： An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the locking mechanism prevents the needle from being placed in the injection position.
摘要翻译： 提供注射装置。 该装置包括具有限定第一开口的第一端的壳体。 柱塞被容纳在壳体的第一开口内以在第一和第二位置之间移动。 盒体设置在壳体中，并且具有用作药物的储存器的内部。 输送针设置在壳体内并且经由可中断流体通道与储存器流体连通。 锁定机构设置在壳体中。 在柱塞的第一位置，输送针由柱塞封闭，并且在柱塞的第二位置中，输送针被放置在注射位置，并且柱塞启动锁定机构，由此当柱塞返回到第一位置时，锁定 机构防止针头置于注射位置。
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公开(公告)号：US08157768B2
公开(公告)日：2012-04-17
申请号：US12980574
申请日：2010-12-29
CPC分类号： A61M5/3234 , A61M5/2033 , A61M5/2429 , A61M5/46 , A61M5/502 , A61M2005/2013 , A61M2005/3247 , A61M2037/0023
摘要： An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the .locking mechanism prevents the needle from being placed in the injection position.
摘要翻译： 提供注射装置。 该装置包括具有限定第一开口的第一端的壳体。 柱塞被容纳在壳体的第一开口内以在第一和第二位置之间移动。 盒体设置在壳体中，并且具有用作药物的储存器的内部。 输送针设置在壳体内并且经由可中断流体通道与储存器流体连通。 锁定机构设置在壳体中。 在柱塞的第一位置，输送针由柱塞封闭，并且在柱塞的第二位置中，输送针位于注射位置，并且柱塞启动锁定机构，由此当柱塞返回到第一位置时。 锁定机构防止针头被置于注射位置。
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公开(公告)号：US20110098641A1
公开(公告)日：2011-04-28
申请号：US12980574
申请日：2010-12-29
IPC分类号： A61M5/50
CPC分类号： A61M5/3234 , A61M5/2033 , A61M5/2429 , A61M5/46 , A61M5/502 , A61M2005/2013 , A61M2005/3247 , A61M2037/0023
摘要： An injection device is provided. The device includes a housing having a first end defining a first opening. A plunger is received within the first opening of the housing to move between first and second positions. A cartridge is disposed in the housing and has an interior serving as a reservoir for a drug. A delivery needle is disposed within the housing and is in fluid communication with the reservoir via an interruptible fluid channel. A locking mechanism is disposed in the housing. In the first position of the plunger the delivery needle is enclosed by the plunger and in the second position of the plunger the delivery needle is placed in an injection position and the plunger activates the locking mechanism whereby when the plunger returns to the first position the locking mechanism prevents the needle from being placed in the injection position.
摘要翻译： 提供注射装置。 该装置包括具有限定第一开口的第一端的壳体。 柱塞被容纳在壳体的第一开口内以在第一和第二位置之间移动。 盒体设置在壳体中，并且具有用作药物的储存器的内部。 输送针设置在壳体内并且经由可中断流体通道与储存器流体连通。 锁定机构设置在壳体中。 在柱塞的第一位置，输送针由柱塞封闭，并且在柱塞的第二位置中，输送针被放置在注射位置，并且柱塞启动锁定机构，由此当柱塞返回到第一位置时，锁定 机构防止针头置于注射位置。
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7.发明授权公开(公告)号：US06808506B2
公开(公告)日：2004-10-26
申请号：US10357502
申请日：2003-02-04
申请人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
发明人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
IPC分类号： A61B1720
CPC分类号： A61M5/425 , A61M5/14244 , A61M5/3007 , A61M5/46 , A61M37/0015
摘要： An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. The dermal-access member extends at least 1 mm from the protrusion. A mechanism drives the device against the skin at a calculated speed of about 6 m/s to about 18 m/s.
摘要翻译： 提供了一种用于通过至少一层皮肤递送或取出流体的装置。 一种装置包括具有顶面，底面，侧缘和至少一个通道的主体。 底面包括与第一表面区域相邻并且与第一表面区域第一距离凹陷的第一表面区域和第二表面区域。 底面还包括设置在第二表面区域上的至少一个凸起突起。 突起具有从第一表面的高度大于第一距离。 在突起中提供至少一个真皮进入构件，并且与通道流体连通以输送或抽出流体。 真皮进入构件从突起延伸至少1mm。 机构以约6m / s至约18m / s的计算速度驱动装置抵靠皮肤。
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8.发明授权公开(公告)号：US07083592B2
公开(公告)日：2006-08-01
申请号：US10951217
申请日：2004-09-27
申请人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
发明人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
IPC分类号： A61B17/20
CPC分类号： A61M5/425 , A61M5/14244 , A61M5/3007 , A61M5/46 , A61M37/0015
摘要： An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. The dermal-access member extends at least 1 mm from the protrusion. A mechanism drives the device against the skin at a calculated speed of about 6 m/s to about 18 m/s.
摘要翻译： 提供了一种用于通过至少一层皮肤递送或取出流体的装置。 一种装置包括具有顶面，底面，侧缘和至少一个通道的主体。 底面包括与第一表面区域相邻并且与第一表面区域第一距离凹陷的第一表面区域和第二表面区域。 底面还包括设置在第二表面区域上的至少一个凸起突起。 突起具有从第一表面的高度大于第一距离。 在突起中提供至少一个真皮进入构件，并且与通道流体连通以输送或抽出流体。 真皮进入构件从突起延伸至少1mm。 机构以约6m / s至约18m / s的计算速度驱动装置抵靠皮肤。
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9.发明申请Device and method for delivering or withdrawing a substance through the skin 审中-公开通过皮肤递送或取出物质的装置和方法公开(公告)号：US20100292648A1
公开(公告)日：2010-11-18
申请号：US12845373
申请日：2010-07-28
申请人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
发明人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
IPC分类号： A61M5/00
CPC分类号： A61M5/425 , A61M5/14244 , A61M5/3007 , A61M5/46 , A61M37/0015
摘要： An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid.
摘要翻译： 提供了一种用于通过至少一层皮肤递送或取出流体的装置。 一种装置包括具有顶面，底面，侧缘和至少一个通道的主体。 底面包括与第一表面区域相邻并且与第一表面区域第一距离凹陷的第一表面区域和第二表面区域。 底面还包括设置在第二表面区域上的至少一个凸起突起。 突起具有从第一表面的高度大于第一距离。 在突起中提供至少一个真皮进入构件，并且与通道流体连通以输送或抽出流体。
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10.发明申请Device and method for delivering or withdrawing a substance through the skin 审中-公开通过皮肤递送或取出物质的装置和方法公开(公告)号：US20090112181A1
公开(公告)日：2009-04-30
申请号：US12341589
申请日：2008-12-22
申请人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
发明人： Alexander G. Lastovich , James K. Fentress , Julia Griggs , Ronald J. Pettis , Diane Sutter , Frank E. Martin , M. Ishaq Haider
IPC分类号： A61M5/32
CPC分类号： A61M5/425 , A61M5/14244 , A61M5/3007 , A61M5/46 , A61M37/0015
摘要： An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid.
摘要翻译： 提供了一种用于通过至少一层皮肤递送或取出流体的装置。 一种装置包括具有顶面，底面，侧缘和至少一个通道的主体。 底面包括与第一表面区域相邻并且与第一表面区域第一距离凹陷的第一表面区域和第二表面区域。 底面还包括设置在第二表面区域上的至少一个凸起突起。 突起具有从第一表面的高度大于第一距离。 在突起中提供至少一个真皮进入构件，并且与通道流体连通以输送或抽出流体。
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