公开(公告)号：US20250114593A1

公开(公告)日：2025-04-10

申请号：US18933759

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR ,  David LINSKY

IPC: A61M60/855 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/408 ,  A61M60/833

Abstract: Apparatus and methods are described including a delivery catheter and a delivery tube configured to extend from outside a subject's body into the subject's left ventricle via the delivery catheter. A locking unit is configured to couple to a proximal end of the delivery catheter and the delivery tube is configured to pass through the locking unit. The locking unit includes at least one internal seal configured to surround the delivery tube and to inhibit backflow of blood of the subject, from the delivery catheter, through the locking unit. The locking unit also includes a clip, which has only two states, which consist of a closed state, in which the clip grips the delivery tube so as to inhibit movement of the delivery tube relative to the delivery catheter, and an open state, in which the clip does not grip the delivery tube. Other applications are also described.

公开(公告)号：US20240277990A1

公开(公告)日：2024-08-22

申请号：US18635275

申请日：2024-04-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/216 ,  A61M60/408 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/178 ,  A61M60/216 ,  A61M60/408 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

Abstract: Apparatus and methods are provided, including a left-ventricular assist device that includes an impeller configured for insertion into a subject's left ventricle. A delivery tube passes through the subject's aorta, from outside the subject into the left ventricle. The delivery tube includes an outer layer that varies along a length of the delivery tube such that a flexural rigidity of the delivery tube at a first portion of the delivery tube, which is configured to traverse the aortic valve, is less than the flexural rigidity at a second portion, which is configured to traverse at least a portion of the aortic arch, and the flexural rigidity at the second portion is less than the flexural rigidity at a third portion, which is configured to traverse the descending aorta. Other applications are also described.

公开(公告)号：US20250073446A1

公开(公告)日：2025-03-06

申请号：US18933749

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/216 ,  A61M60/17 ,  A61M60/414 ,  A61M60/825 ,  A61M60/90

Abstract: Apparatus and methods are described including a solid axial shaft having a shaft diameter that is less than 0.8 mm, an impeller configured for insertion into a left ventricle of a heart of a subject and coupled to the axial shaft, and a hollow drive cable coupled, at a distal end of the drive cable, to the axial shaft, and configured to rotate so as to rotate the axial shaft, thereby causing the impeller to pump blood of the subject from the left ventricle. Other applications are also described.

公开(公告)号：US20250065104A1

公开(公告)日：2025-02-27

申请号：US18933729

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/237

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller, which includes a proximal bushing disposed over the axial shaft, a distal bushing disposed over the axial shaft distally from the proximal bushing, and one or more blades. Each of the blades includes a single inner helical elongate element, a single outer helical elongate element, and a film of material extending between the inner helical elongate element and the outer helical elongate element. The blades are proximally coupled to the proximal bushing and distally coupled to the distal bushing such that, as the axial shaft rotates, the blades rotate, thereby pumping blood of the subject. Other applications are also described.

公开(公告)号：US20240269457A1

公开(公告)日：2024-08-15

申请号：US18640222

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/17 ,  A61M60/13 ,  A61M60/414 ,  A61M60/554 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81

CPC classification number: A61M60/17 ,  A61M60/13 ,  A61M60/414 ,  A61M60/554 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3331 ,  A61M2205/502 ,  A61M2210/125 ,  A61M2230/30

Abstract: Apparatus and methods are described including a device configured for insertion into a left ventricle of a heart of a subject. A delivery tube is coupled to the device and configured to traverse an aortic arch of the subject while the device is within the left ventricle. An elongation-resistant fiber runs axially along the delivery tube so as to bias an orientation of the delivery tube while the delivery tube traverses the aortic arch such that the elongation-resistant fiber is disposed inside a curve of the aortic arch, thereby biasing an orientation of the device. Other applications are also described.

公开(公告)号：US20240261563A1

公开(公告)日：2024-08-08

申请号：US18637655

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/414 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/414 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825 ,  A61M2039/1077

Abstract: Apparatus and methods are described including inserting a drive-cable end of a drive cable, which includes a plurality of coiled wires, and a hollow-shaft end of a hollow shaft, which hollow-shaft end is shaped to define multiple shaft pores, into opposing ends of a coupling tube having a wall shaped to define multiple tabs. The drive cable is coupled to the shaft by pushing at least some of the tabs into the shaft pores, respectively. Other applications are also described.

公开(公告)号：US20240261562A1

公开(公告)日：2024-08-08

申请号：US18635286

申请日：2024-04-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/414 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/857

CPC classification number: A61M60/414 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/857

Abstract: Apparatus and methods are provided, including inserting a drive-cable-bearing tube, which includes one or more inwardly-facing ceramic portions, into a body of a subject and through an aorta of the subject, such that the inwardly-facing ceramic portions are within an aortic arch of the subject, while a drive cable, which is coupled to an intracorporeal device at a distal end of the drive-cable-bearing tube and includes one or more outwardly-facing ceramic portions, passes through the drive-cable-bearing tube such that the outwardly-facing ceramic portions are aligned with the inwardly-facing ceramic portions. The drive cable is rotated within the drive-cable-bearing tube, thereby rotating the intracorporeal device, while the outwardly-facing ceramic portions are aligned with the inwardly-facing ceramic portions. Other applications are also described.

公开(公告)号：US20250073445A1

公开(公告)日：2025-03-06

申请号：US18933745

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/216 ,  A61M60/122 ,  A61M60/414 ,  A61M60/825 ,  A61M60/90

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. Proximal and distal radial bearings surround the axial shaft and are configured to radially stabilize the axial shaft while the axial shaft rotates. Proximal and distal sleeves, which are less flexible than the axial shaft, are disposed around the axial shaft, such that the proximal and distal sleeves contact the proximal and distal radial bearings, respectively, as the axial shaft rotates. A ratio between a length of the axial shaft and a combined length of the proximal sleeve and distal sleeve is between 2:1 and 6:1. Other applications are also described.

公开(公告)号：US20240285928A1

公开(公告)日：2024-08-29

申请号：US18635292

申请日：2024-04-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/237 ,  A61M60/174 ,  A61M60/857

CPC classification number: A61M60/237 ,  A61M60/174 ,  A61M60/857

Abstract: Apparatus and methods are provided, including inserting an impeller and a delivery tube into a subject's body, the delivery tube including a braid having a pick density that varies along the delivery tube's length such that a flexural rigidity of the delivery tube at a first portion of the delivery tube is less than the flexural rigidity at a second portion of the delivery tube, and the flexural rigidity at the second portion is less than the flexural rigidity at a third portion of the delivery tube. The impeller and delivery tube are positioned such that the impeller is disposed within the subject's left ventricle and the delivery tube passes the subject's aorta into the left ventricle. Using a drive cable, which passes through the delivery tube, the impeller is rotated so as to pump blood from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20240277999A1

公开(公告)日：2024-08-22

申请号：US18639094

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/825 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/865

CPC classification number: A61M60/825 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion, over a guidewire, into a subject's body, and for rotation within the subject's body. The axial shaft is shaped to define a shaft lumen for passage of the guidewire therethrough. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A thrust bearing is disposed distally from the axial shaft so as to inhibit distal movement of the axial shaft beyond the thrust bearing. The thrust bearing is shaped to define a bearing lumen that is configured to be continuous with the shaft lumen. At least a portion of the bearing lumen is frustoconically-shaped, a wider end of the frustoconically-shaped portion of the bearing lumen facing distally. Other applications are also described.