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公开(公告)号：US11560601B2
公开(公告)日：2023-01-24
申请号：US16864946
申请日：2020-05-01
发明人： Rajinder Singh , Leslie Ooi Cheng Li , Leslie Low Eng Ti , Rahimah Abdul Rahman , Meilina Ong Abdullah , Jayanthi Nagappan , Rozana Rosli , Mohd Amin Ab Halim , Rajanaidu Nookiah , Chan Kuang Lim , Norazah Azizi , Ravigadevi Sambanthamurthi , Rob Martienssen , Steven W. Smith , Nathan D. Lakey , Andrew Van Brunt , Jared Ordway , Michael Hogan , Chunyan Wang
IPC分类号： C12Q1/6895 , C12Q1/6827
摘要： Methods, compositions, and kits for predicting and controlling fruit color in palm.
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公开(公告)号：US11517607B2
公开(公告)日：2022-12-06
申请号：US16507838
申请日：2019-07-10
发明人： Robert P. Weinberg , Chokyun Rha , Anthony J. Sinskey , Yew Ai Tan , Ravigadevi Sambanthamurthi
IPC分类号： A61K36/889 , A23D9/007 , A23L33/115 , A23L33/105 , A61K36/00
摘要： Present invention discloses an oil palm composition for use in prevention or treatment of Alzheimer's disease. The composition is useful in impeding formation of neurotoxic peptide. Present invention can be used in preparation of a medicament in a therapeutic effective amount for prevention or treatment of Alzheimer's disease and diseases related thereto.
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公开(公告)号：US20180236022A1
公开(公告)日：2018-08-23
申请号：US15897896
申请日：2018-02-15
发明人： Ravigadevi Sambanthamurthi , Yew Ai Tan , Syed Fairus Syed Abu Bakar , Che Anishas Che Idris , Soon Sen Leow , Mohd Jamil Elias , Wan Saridah Wan Omar , Mohd Sofian Mohamad Ideris , Jabariah Md. Ali
IPC分类号： A61K36/889 , A61K31/05
CPC分类号： A61K36/889 , A61K31/05 , A61K2236/00
摘要： This disclosure is directed to a novel bioactive compound obtained from oil palm based materials and compositions containing said bioactive compound. The bioactive compound obtained in accordance with the present invention has a molecular mass of 482. The bioactive compound also has potent HIV reverse transcriptase activity and antioxidant activity.
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公开(公告)号：US09962421B2
公开(公告)日：2018-05-08
申请号：US15621078
申请日：2017-06-13
发明人： T. G. Sambandan , ChoKyun Rha , Anthony J. Sinskey , Ravigadevi Sambanthamurthi , Yew Ai Tan , Kalyana Sundram P. Manickam , Mohd Basri Wahid
IPC分类号： A61K36/889
CPC分类号： A61K36/889
摘要： A composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives extracted from any part of oil palm including but not confined to the vegetation liquor of palm oil milling and palm oil mill effluent, and a method for use in the preparation of a composition containing caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives. The method includes the steps of pre-concentrating an extract containing the caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives and isolating said caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives from said extract by liquid chromatography, wherein the elution activity of said caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, caffeoylshikimic acids and their derivatives vary depending on the stationary phase and the composition of the mobile phase.
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公开(公告)号：US20150315662A1
公开(公告)日：2015-11-05
申请号：US14701425
申请日：2015-04-30
发明人： Meilina Ong Abdullah , Ooi Siew Eng , Leslie Low Eng Ti , Rajinder Singh , Rajanaidu Nookiah , Ravigadevi Sambanthamurthi , Nan Jiang , Steven W. Smith , Nathan D. Lakey , Rob Martienssen , Jared Ordway , Michael Hogan
IPC分类号： C12Q1/68 , G06F19/22 , C12N15/113
CPC分类号： G06F19/22 , C12N15/113 , C12N2310/14 , C12Q1/6895 , C12Q2537/164 , C12Q2600/13 , C12Q2600/154 , C12Q2600/158 , C12Q2600/16 , G06F19/18
摘要： Methods, compositions, kits, and computer program code are provided for predicting somaclonal abnormality (e.g., a Mantled phenotype) in a plant and or sorting plants based on the predicted presence or absence of somaclonal abnormality.
摘要翻译： 提供方法，组合物，试剂盒和计算机程序代码，用于基于预测的存在或不存在体细胞异常异常来预测植物中的体细胞异常（例如，Mantled表型）和/或分选植物。
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公开(公告)号：US20150037793A1
公开(公告)日：2015-02-05
申请号：US14334825
申请日：2014-07-18
发明人： Rajinder SINGH , Leslie Low Eng Ti , Leslie Ooi Cheng Li , Meilina Ong Abdullah , Rajanaidu Nookiah , Ravigadevi Sambanthamurthi , Jared Ordway , Nathan D. Lakey , Steven W. Smith , Rob Martienssen , Michael Hogan
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895 , C12Q2600/13 , C12Q2600/158
摘要： Methods, compositions, and kits for determining SHELL genotype and predicting shell fruit form of oil palm plants.
摘要翻译： 用于确定SHELL基因型和预测油棕榈植物壳壳形式的方法，组合物和试剂盒。
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公开(公告)号：US20130131158A1
公开(公告)日：2013-05-23
申请号：US13633041
申请日：2012-10-01
IPC分类号： A61K36/889 , A61K31/192 , A61K31/353 , A61K31/047
CPC分类号： A61K36/889 , A61K31/047 , A61K31/192 , A61K31/353
摘要： The present invention relates to a composition of phenolic antioxidants obtained from oil palm, and more particularly this invention relates to a composition for promoting immunity in general and most essentially against Human Immunodeficiency Virus (HIV) related infections. Accordingly, the composition having the said oil palm compounds can effectively inhibit various viruses, further supporting oil palm compounds as one of the broad spectrum antiviral drugs.
摘要翻译： 本发明涉及由油棕获得的酚类抗氧化剂的组合物，更具体地说，本发明涉及一般用于促进免疫的组合物，最基本上是针对人类免疫缺陷病毒（HIV）相关感染的组合物。 因此，具有所述油棕榈化合物的组合物可以有效地抑制各种病毒，进一步支持作为广谱抗病毒药物之一的油棕榈化合物。
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公开(公告)号：US11371104B2
公开(公告)日：2022-06-28
申请号：US16828452
申请日：2020-03-24
发明人： Rajinder Singh , Leslie Low Eng Ti , Leslie Ooi Cheng Li , Meilina Ong Abdullah , Rajanaidu Nookiah , Ravigadevi Sambanthamurthi , Steven W. Smith , Nathan D. Lakey , Rob Martienssen , Jared Ordway , Michael Hogan
IPC分类号： A01H1/04 , C12Q1/6895 , C12N15/82 , C07K14/415
摘要： Nucleic acid sequences for predicting and controlling shell phenotype in palm.
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公开(公告)号：US11000564B2
公开(公告)日：2021-05-11
申请号：US15898477
申请日：2018-02-17
发明人： Soon Sen Leow , Ravigadevi Sambanthamurthi , Yew Ai Tan , Kalyana Sundram P. Manickam , Mohd Basri wahid
IPC分类号： A61K36/889 , A61K31/05
摘要： A composition comprising extracts containing oil palm phenolics in an amount effective for use in a method of reducing cholesterol biosynthesis and thus preventing obesity. The composition up regulates fatty acid beta oxidation and down regulates cholesterol biosynthesis in livers. The composition is useful for prevention of obesity associated diseases. The composition delays the onset of obesity and attenuates the inflammatory response of atherogenic diet, whereby the composition aids to suppress the inflammatory response thereby ameliorating artherosclerosis. The composition delays weight gain or obesity thereby preventing the effects of dyslipidemia.
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10.发明授权公开(公告)号：US10342844B2
公开(公告)日：2019-07-09
申请号：US15400556
申请日：2017-01-06
IPC分类号： A61K36/00 , A61K36/889 , A61K45/06 , A61K31/05 , A23L33/105 , A61K9/00
摘要： Present invention relates to a composition to inhibit cancer cell proliferation, wherein said composition comprises oil palm extracts. The composition is useful for prevention of pancreatic cancer by inhibiting clonogenicity, inducing apoptosis, regulating gene expression, inducing anti-invasive effect, and induces cell cycle arrest in S phase. Present invention also discloses a composition that inhibits NF-κB activity and reduces cell invasion, cell migration and metastasis. Present invention further discloses the use of therapeutically effective amount of a composition in inhibiting the growth of pancreatic cancer.
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