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    VENTILATION PATTERN FOR HEMODYNAMIC PARAMETER DETERMINATION DURING MECHANICAL VENTILATION
    1.
    发明申请
    VENTILATION PATTERN FOR HEMODYNAMIC PARAMETER DETERMINATION DURING MECHANICAL VENTILATION 有权

    公开(公告)号：US20210220588A1

    公开(公告)日：2021-07-22

    申请号：US17250055

    申请日：2018-06-11

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61M16/00

    Abstract: A method for changing the effective ventilation of a mechanically ventilated subject to enable or carry out non-invasive determination of hemodynamic parameters is disclosed. The method includes a step of ventilating the subject using a ventilation pattern comprising at least one phase of increased ventilation and at least one phase of decreased ventilation, wherein the phase of decreased ventilation comprises at least one prolonged breath including a respiratory pause (IRP). The respiratory pause is initiated when the lung pressure (Palv) of the subject is between a minimum lung pressure and a maximum lung pressure of the subject during the prolonged breath.

    MEDICAL PRESSURE MEASURING DEVICE AND BREATHING APPARATUS
    3.
    发明申请
    MEDICAL PRESSURE MEASURING DEVICE AND BREATHING APPARATUS 审中-公开

    公开(公告)号：US20200155784A1

    公开(公告)日：2020-05-21

    申请号：US16615220

    申请日：2017-06-21

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61M16/08 ,  A61M16/00 ,  G01L19/06 ,  G01L9/00

    Abstract: The present disclosure relates to a medical pressure measuring device (100) for measuring a pressure of a pressurized breathing gas supplied to a subject by a breathing apparatus (200). The device (100) comprises a pressure sensor (110) arranged at a point of measurement (195) and configured to measure the pressure of a sample gas at a sampling point (190). The sampling point (190) and the point of measurement (195) are connected by a pressure sampling tube (180) in which a pressure wave of the sample gas can propagate from the sampling point (190) to the point of measurement (195). The pressure sampling tube (180) has a sampling tube volume and an acoustic impedance.The medical pressure measuring device (100) further comprises a damping arrangement (120) arranged to be brought into fluid communication with the pressure sampling tube (180). The damping arrangement (120) comprises a flow restrictor (130) and a receptor chamber arrangement (140). The receptor chamber arrangement (140) comprises a receptor chamber (141). The receptor chamber arrangement (140) is an arrangement for receiving the pressure wave of the sample gas. The flow restrictor (130) correlates to the acoustic impedance of the pressure sampling tube (180) so as to prevent acoustic resonance in the pressure sampling tube (180). The receptor chamber (141) correlates at least to the volume of the pressure sampling tube (180), so as to prevent acoustic resonance in the pressure sampling tube (180).

    ESTIMATION OF MIXED VENOUS OXYGEN SATURATION
    4.
    发明申请
    ESTIMATION OF MIXED VENOUS OXYGEN SATURATION 有权

    公开(公告)号：US20220378323A1

    公开(公告)日：2022-12-01

    申请号：US17755957

    申请日：2019-12-10

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61B5/083 ,  A61M16/00

    Abstract: The present disclosure relates to a method for continuous and noninvasive estimation of mixed venous blood saturation [SvO2] in a mechanically ventilated subject (3). The method comprises the steps of measuring (S1; S10) an expiratory carbon dioxide [CO2] content in expiration gas exhaled by the subject, measuring (S2; S20) an expiratory flow or volume of expiration gas exhaled by the subject, estimating (S3; S30) a cardiac output [CO] or an effective pulmonary blood flow [EPBF] of the subject from the measured expiratory CO2 content and the measured expiratory flow or volume using a capnodynamic Fick method, and estimating (S4; S40) SvO2 based on the estimated CO or the EPBF of the subject.

    Ventilation Pattern for Non-Invasive Determination of ELV, EPBF, Cardiac Output and/or CO2 Content in Venous Blood
    5.
    发明申请
    Ventilation Pattern for Non-Invasive Determination of ELV, EPBF, Cardiac Output and/or CO2 Content in Venous Blood 审中-公开

    公开(公告)号：US20200297956A1

    公开(公告)日：2020-09-24

    申请号：US15780199

    申请日：2015-12-16

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61M16/00

    Abstract: The present invention relates to non-invasive determination of the effective lung volume [ELV], cardiac output, effective pulmonary blood flow [EPBF] and/or the carbon dioxide content of venous blood of a mechanically ventilated subject (3). The subject (3) is ventilated using a ventilation pattern comprising at least one phase of decreased ventilation and at least one phase of increased ventilation, wherein each of said phases comprises at least two breaths during which a level of CO2 expired by said subject assumes a substantially steady state (SS1, SS2). At least one of said phases of decreased and increased ventilation comprises at least a first breath for generating a substantial change in the level of expired CO2 compared to a preceding breath, and at least a second breath being different in duration and/or volume than said first breath, for causing the level of expired CO2 to assume said substantially steady state (SS1, SS2).

    DETERMINATION OF NEUROMUSCULAR EFFICIENCY DURING MECHANICAL VENTILATION
    6.
    发明申请
    DETERMINATION OF NEUROMUSCULAR EFFICIENCY DURING MECHANICAL VENTILATION 审中-公开

    公开(公告)号：US20190351166A1

    公开(公告)日：2019-11-21

    申请号：US16479184

    申请日：2017-02-03

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61M16/00 ,  A61B5/0488 ,  A61B5/087 ,  A61B5/00

    Abstract: The present disclosure relates to a method, computer program and breathing apparatus for determination of at least one physiological parameter including the neuromechanical efficiency [NME] of a patient (3) being mechanically ventilated by the breathing apparatus (1). This is achieved by obtaining (S2, S4) samples of an airway pressure (Paw), a patient flow (Ø), a change in lung volume (V) caused by the patient flow, and an electrical activity of a respiratory muscle of the patient (3), during ventilation of the patient at a first level of ventilatory assist and a second and different level of ventilatory assist, and determining (S5) the at least one physiological parameter, including NME, from the airway pressure samples, the patient flow samples, the samples of the change in lung volume, and the samples of the electrical activity of the respiratory muscle, obtained at the different levels of ventilatory assist.

    AUTOMATIC EVALUATION OF A FILLING VOLUME OF AN OESOPHAGEAL BALLOON CATHETER
    7.
    发明申请
    AUTOMATIC EVALUATION OF A FILLING VOLUME OF AN OESOPHAGEAL BALLOON CATHETER 有权

    公开(公告)号：US20220008698A1

    公开(公告)日：2022-01-13

    申请号：US17310152

    申请日：2019-02-20

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61M25/10 ,  A61M16/04 ,  G16H40/20 ,  G16H20/40 ,  G16H50/70 ,  G16H40/40

    Abstract: The present disclosure relates to a method for automatic evaluation of a filling volume of an oesophageal balloon catheter (26) inserted into a mechanically ventilated patient (3). The method comprises obtaining (S3-S4) samples of an airway pressure, Paw, and an oesophageal pressure, Pes, of the patient during an occlusion period in which respiration of the patient is prevented, evaluating (S5) the filling volume of the oesophageal balloon catheter by determining a ratio, ΔPes/ΔPaw, between Pes and Paw from a regression analysis of the Pes and Paw samples, and communicating (S6) a result of the evaluation to a user.

    LUNG RECRUITMENT IN MECHANICAL VENTILATION
    8.
    发明申请
    LUNG RECRUITMENT IN MECHANICAL VENTILATION 有权

    公开(公告)号：US20210228827A1

    公开(公告)日：2021-07-29

    申请号：US17250049

    申请日：2018-10-17

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Sigun ISRAELSSON ,  Magnus HALLBÄCK ,  Anders HÄGGSTRÖM ,  Mari ANDERSSON

    IPC: A61M16/00 ,  A61M16/08 ,  G16H40/63

    Abstract: A ventilation system includes a breathing apparatus which provides mechanical ventilation to a patient. The breathing apparatus is configured to perform an automated full recruitment manoeuvre, FRM, comprising a recruitment phase and a PEEP titration phase. In the PEEP titration phase the breathing apparatus is configured to gradually decrease the level of PEEP and to deliver a number of breaths at each of a plurality of PEEP levels, monitor at least one parameter from which an optimal PEEP of the patient may be determined, predict whether the optimal PEEP will be possible to reliably determine later on during the PEEP titration phase, and automatically abort the FRM manoeuvre if it is predicted that it will not be possible to reliably determine the optimal PEEP.

    DETERMINATION OF CARDIAC OUTPUT OR EFFECTIVE PULMONARY BLOOD FLOW DURING MECHANICAL VENTILATION
    10.
    发明申请
    DETERMINATION OF CARDIAC OUTPUT OR EFFECTIVE PULMONARY BLOOD FLOW DURING MECHANICAL VENTILATION 审中-公开

    公开(公告)号：US20190142284A1

    公开(公告)日：2019-05-16

    申请号：US16098080

    申请日：2016-05-03

    Applicant: MAQUET CRITICAL CARE AB

    Inventor： Magnus HALLBÄCK

    IPC: A61B5/029 ,  A61B5/0205 ,  A61B5/00 ,  A61M16/00

    Abstract: The present disclosure relates to a method for determination of cardiac output or EPBF of a mechanically ventilated subject (3). The method comprises the steps of introducing (S2) a change in the effective ventilation of the subject (3), measuring (S1) expiratory flow and CO2 during a sequence of analysed breaths during which the effective ventilation of the subject (3) varies, and determining (S3) the cardiac output or EPBF of the subject (3) using the flow and CO2 measurements. The method further comprises the steps of measuring (S1) also a relative variation in cardiac output or EPBF during the sequence of analysed breaths, and using the relative variation in the determination (S3) of cardiac output or EPBF.

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