DEVICE, SYSTEM AND METHOD FOR COLLECTING AND ELUTING AEROSOL PARTICLES FROM HUMAN BREATHS FOR ANALYSIS

    公开(公告)号:US20240215961A1

    公开(公告)日:2024-07-04

    申请号:US18556204

    申请日:2022-05-05

    申请人: Avelo AG

    发明人: Tobias Broger

    IPC分类号: A61B10/00 A61B5/08 A61B5/097

    摘要: A device, system and method for collecting and eluting aerosol particles contained in a breath sample of a human or animal for the purpose of sampling non-volatile respiratory pathogens present in the breath sample. In at least some embodiments, the present invention provides such a device, system and method to collect, preserve, concentrate and release pathogen-specific biomarkers from breath aerosols for the subsequent analysis with immunoassays and molecular assays for the clinical diagnosis of respiratory tract infections in humans. The sampling device comprises an aqueous solution dissolvable polymer membrane installed in a housing of the sampling device in the flow path of the breath aerosol that sorbs the aerosol particles. The sampling device further comprises an engagement means for releasably engaging an elution device to the housing for introducing an aqueous solution into the housing and for dissolving the polymer membrane upon contact with the aqueous solution.