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公开(公告)号：US10117967B2
公开(公告)日：2018-11-06
申请号：US15729668
申请日：2017-10-11
IPC分类号： A61L27/20 , A61L27/18 , A61L27/38 , A61L27/22 , C08L67/02 , C07K14/78 , C12N5/077 , C08B37/08 , C08J3/075
摘要： The embodiments herein disclose a method of fabricating composite scaffolds for skin tissue regeneration. The methacrylated hyaluronic acid (HAMA) and methacrylated gelatin (GelMA) are synthesized. The poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds are synthesized. The hydrogel is synthesized. The composite scaffold comprising hydrogel and poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds is fabricated. A plurality of physico-chemical characteristics of the composite scaffold comprising hydrogel and poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds are analysed. The physico-chemical characteristics comprises mechanical properties, swelling ratio and enzymatic degradation and scanning electron microscope imaging. The fibroblast cells are encapsulated within the composite scaffold comprising hydrogel and poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds and hydrogels. The fibroblast cells are seeded on composite scaffold and PGS-PCL scaffold. The fibroblast cell viability, fibroblast cell attachment, fibroblast cell spreading, fibroblast cell proliferation and fibroblast cell metabolism are analysed in composite scaffolds, PGS-PCL scaffolds and hydrogels.
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2.发明申请公开(公告)号：US20100076435A1
公开(公告)日：2010-03-25
申请号：US12239780
申请日：2008-09-28
CPC分类号： A61B17/6475
摘要： A Mini External Fixate device is disclosed in closed operations in order to fix fractures of elbow bone especially olecranon and cure its problems including mal-unions and non-unions, correcting elbow deformities, lengthening the bone length up to 5 cm. The device comprises three curved plates which are connected by a threaded rod. The device may further comprise two half pin consuls which go through each curved plate in one direction. The half pin consuls may extend as far as they are connected to the fracture, while they don't reach the other side of the bone. Half pins may be used instead of full pins in this device. The half pin consuls may be attached to the curved plate by means of a wire fixation bolt. A hinge may be attached to the extreme of the threaded rod.
摘要翻译： 公开了一种微型外固定装置，用于固定肘骨特别是鹰嘴骨折，治愈其不适症状，纠正肘关节畸形，延长骨长达5厘米。 该装置包括通过螺纹杆连接的三个弯曲板。 该装置还可以包括在一个方向上穿过每个弯曲板的两个半针领带。 半针领带可以延伸到与骨折相连的距离，而它们不会到达骨的另一侧。 这个设备可以使用半引脚而不是全引脚。 半针总成可以通过线固定螺栓附接到弯曲板。 铰链可以连接到螺杆的极端。
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3.发明授权公开(公告)号：US08083740B2
公开(公告)日：2011-12-27
申请号：US12239780
申请日：2008-09-28
IPC分类号： A61F5/04
CPC分类号： A61B17/6475
摘要： A Mini External Fixate device is disclosed in closed operations in order to fix fractures of elbow bone especially olecranon and cure its problems including mal-unions and non-unions, correcting elbow deformities, lengthening the bone length up to 5 cm. The device comprises three curved plates which are connected by a threaded rod. The device may further comprise two half pin consuls which go through each curved plate in one direction. The half pin consuls may extend as far as they are connected to the fracture, while they don't reach the other side of the bone. Half pins may be used instead of full pins in this device. The half pin consuls may be attached to the curved plate by means of a wire fixation bolt. A hinge may be attached to the extreme of the threaded rod.
摘要翻译： 公开了一种微型外固定装置，用于固定肘骨特别是鹰嘴骨折，治愈其不适症状，纠正肘关节畸形，延长骨长达5厘米。 该装置包括通过螺纹杆连接的三个弯曲板。 该装置还可以包括在一个方向上穿过每个弯曲板的两个半针领带。 半针领带可以延伸到与骨折相连的距离，而它们不会到达骨的另一侧。 这个设备可以使用半引脚而不是全引脚。 半针总成可以通过线固定螺栓附接到弯曲板。 铰链可以连接到螺杆的极端。
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