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1.发明授权Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof 有权包含全身作用活性剂的杀虫剂口服兽药组合物，其方法和用途公开(公告)号：US09259417B2
公开(公告)日：2016-02-16
申请号：US14627499
申请日：2015-02-20
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska
IPC: A61K31/42 , A61K31/194 , A61K9/00 , A61K45/06 , C07D261/04 , A61K31/4985 , A61K31/7048 , A61K31/365 , A61K31/27 , A61K31/437 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/44
CPC classification number: A61K31/42 , A01N43/80 , A23K20/00 , A61K9/0056 , A61K9/0068 , A61K31/194 , A61K31/27 , A61K31/325 , A61K31/365 , A61K31/437 , A61K31/4985 , A61K31/7048 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/42 , A61K47/44 , C07D261/04 , A61K2300/00
Abstract: This invention relates to veterinary compositions for treating and/or preventing fleas or ticks infection or infestation in an animal comprising an isoxazoline active agent of Formula (II): or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.
Abstract translation: 本发明涉及用于治疗和/或预防动物中跳蚤或蜱感染或感染的兽用组合物，其包含式（II）的异恶唑啉活性剂：或其药学上可接受的盐; 和药学上可接受的载体。
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2.发明授权Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof 有权包含全身作用活性剂的杀虫剂口服兽药组合物，其方法和用途公开(公告)号：US09233100B2
公开(公告)日：2016-01-12
申请号：US13754969
申请日：2013-01-31
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC: A61K45/06 , A61K31/27 , A61K31/365 , A61K31/42 , A61K31/4985 , A61K31/7048 , C07D261/04 , A61K31/437 , A61K9/00 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/44 , A61K31/194
CPC classification number: A61K31/42 , A01N43/80 , A23K20/00 , A61K9/0056 , A61K9/0068 , A61K31/194 , A61K31/27 , A61K31/325 , A61K31/365 , A61K31/437 , A61K31/4985 , A61K31/7048 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/42 , A61K47/44 , C07D261/04 , A61K2300/00
Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
Abstract translation: 本发明涉及用于对抗动物体内寄生虫和内寄生虫的口服兽药组合物，其包含与药学上可接受的载体组合的至少一种全身作用的活性剂。 本发明还提供了用于消除，控制和预防动物中的寄生虫感染和侵染的改进方法，包括将本发明的组合物施用于有需要的动物。
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3.发明申请LONG-ACTING INJECTABLE FORMULATIONS COMPRISING AN ISOXAZOLINE ACTIVE AGENT, METHODS AND USES THEROF 审中-公开包含ISOXAZOLINE活性剂的长效注射剂配方，其方法和用途公开(公告)号：US20160256442A1
公开(公告)日：2016-09-08
申请号：US15054260
申请日：2016-02-26
Applicant: MERIAL, INC.
Inventor： Susan Mancini Cady , Peter Cheifetz , Izabela Galeska
Abstract: This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.
Abstract translation: 本发明涉及用于对抗动物寄生虫的长效注射制剂，其包含至少一种异恶唑啉活性剂，泊洛沙姆和共溶剂。 本发明还提供了用于消除，控制和预防动物中的寄生虫感染和侵染的改进方法，包括将本发明的长效注射制剂施用于有需要的动物。
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4.发明申请公开(公告)号：US20190105305A1
公开(公告)日：2019-04-11
申请号：US15936778
申请日：2018-03-27
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC: A61K31/42 , A61K31/365 , A61K31/4985 , C07D261/04 , A61K45/06 , A23K20/00 , A61K47/42 , A61K31/325 , A01N43/80 , A61K31/194 , A61K47/44 , A61K47/36 , A61K47/32 , A61K47/14 , A61K9/00 , A61K47/12 , A61K47/10 , A61K31/437 , A61K31/27 , A61K31/7048
Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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5.发明申请公开(公告)号：US20160143285A1
公开(公告)日：2016-05-26
申请号：US15009996
申请日：2016-01-29
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC: A01N43/80
Abstract: This invention relates to veterinary compositions for treating and/or preventing fleas or ticks infection or infestation in an animal comprising an isoxazoline active agent of Formula (II): or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20180185336A1
公开(公告)日：2018-07-05
申请号：US15904798
申请日：2018-02-26
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC: A61K31/42 , A61K31/365 , A61K31/4985 , A61K31/27 , A61K31/437 , A61K9/00 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/44 , A61K31/7048 , C07D261/04 , A61K45/06 , A23K20/00 , A61K47/42 , A61K31/325 , A01N43/80 , A61K31/194
Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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公开(公告)号：US09931320B2
公开(公告)日：2018-04-03
申请号：US14977680
申请日：2015-12-22
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC: A61K31/42 , A61K45/06 , A61K47/42 , A61K31/325 , A61K31/365 , A61K31/7048 , A61K31/4985 , A61K9/00 , A61K47/36 , C07D261/04 , A61K31/27 , A61K31/437 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/44 , A61K31/194 , A01N43/80 , A23K20/00
CPC classification number: A61K31/42 , A01N43/80 , A23K20/00 , A61K9/0056 , A61K9/0068 , A61K31/194 , A61K31/27 , A61K31/325 , A61K31/365 , A61K31/437 , A61K31/4985 , A61K31/7048 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/42 , A61K47/44 , C07D261/04 , A61K2300/00
Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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8.发明申请EXTENDED RELEASE INJECTABLE FORMULATIONS COMPRISING AN ISOXAZOLINE ACTIVE AGENT, METHODS AND USES THEREOF 审中-公开包含ISOXAZOLINE活性剂的扩展性释放的制剂，其方法和用途公开(公告)号：US20170020848A1
公开(公告)日：2017-01-26
申请号：US15092491
申请日：2016-04-06
Applicant: MERIAL INC.
Inventor： Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Loic Le Hir de Fallois
CPC classification number: A61K31/42 , A61K9/00 , A61K9/0019 , A61K31/422 , A61K47/10 , A61K47/22 , A61K2300/00
Abstract: This invention relates to extended release injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a pharmaceutically acceptable polymer, and a solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the extended release injectable formulations of the invention to the animal in need thereof.
Abstract translation: 本发明涉及用于对抗动物寄生虫的延长释放可注射制剂，其包含至少一种异恶唑啉活性剂，药学上可接受的聚合物和溶剂。 本发明还提供了用于消除，控制和预防动物中的寄生虫感染和侵染的改进方法，包括向有需要的动物施用本发明的延长释放可注射制剂。
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9.发明申请公开(公告)号：US20170239218A1
公开(公告)日：2017-08-24
申请号：US15441297
申请日：2017-02-24
Applicant: MERIAL INC.
Inventor： Loic Patrick Le Hir de Fallois , Charles Q. Meng , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska
IPC: A61K31/415 , A61K9/00 , A61K47/10 , A01N43/80
CPC classification number: A61K31/415 , A01N43/80 , A61K9/0019 , A61K9/0095 , A61K9/08 , A61K9/10 , A61K9/107 , A61K31/42 , A61K31/422 , A61K47/10 , A61K47/14 , C07D261/04 , C07D413/04 , C07D471/04 , C07D491/107 , A01N25/02 , A01N25/22
Abstract: This invention relates to long-acting injectable compositions for combating parasites in animals, comprising at least one isoxazoline active agent, a liquid PEG and/or a neutral oil, optionally a co-solvent, and optionally a pharmaceutically acceptable additive or excipient. This invention also provides new isoxazoline active agents with long-lasting efficacy against ectoparasites. The invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the novel isoxazoline compounds and long-acting injectable compositions of the invention to the animal in need thereof.
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公开(公告)号：US20160374994A1
公开(公告)日：2016-12-29
申请号：US14977680
申请日：2015-12-22
Applicant: MERIAL INC.
Inventor： Mark David Soll , Diane Larsen , Susan Mancini Cady , Peter Cheifetz , Izabela Galeska , Saijun Gong
IPC: A61K31/42 , A61K45/06 , A61K47/42 , A61K31/325 , A61K31/365 , A61K31/7048 , A61K31/4985 , A61K9/00 , A61K47/36
CPC classification number: A61K31/42 , A01N43/80 , A23K20/00 , A61K9/0056 , A61K9/0068 , A61K31/194 , A61K31/27 , A61K31/325 , A61K31/365 , A61K31/437 , A61K31/4985 , A61K31/7048 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/42 , A61K47/44 , C07D261/04 , A61K2300/00
Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
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