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公开(公告)号:US20030186871A1
公开(公告)日:2003-10-02
申请号:US10321204
申请日:2002-12-16
申请人: METABOLEX, INC.
发明人: Steve Waters , Shonna Moodie , Brian Lavan , Thomas A. Gustafson
IPC分类号: A61K038/24 , C12Q001/68 , G01N033/53 , G01N033/567
CPC分类号: C12Q1/26 , G01N33/6893 , G01N33/88 , G01N2500/00 , G01N2500/02 , G01N2800/042
摘要: The present invention provides compositions and methods for diagnosing and treating diabetes, insulin resistance and dyslipidemia. In particular, the invention provides methods of identifying modulators of AKR1C as well as methods of diagnosing diabetes by measuring the levels of AKR1C or 9null, 11null-PGF2null in a patient.