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公开(公告)号:US20190177281A1
公开(公告)日:2019-06-13
申请号:US16099141
申请日:2017-05-02
申请人: Sromovasam THIRUMALAI RAJAN , Sajja ESWARAIAH , Sagyam RAJESHWAR REDDY , Macharla PRABHAKAR , Boge RAJESHAM , MSN LABORATORIES PRIVATE LIMITED
发明人: Srinivasan Thirumalai RAJAN , Eswaraiah SAJJA , Rajeshwar Reddy SAGYAM , Prabhakar MACHARLA , Rajesham BOGE
IPC分类号: C07D233/64
摘要: The present invention relates to an improved process for the preparation of 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid compound of formula-1, and polymorphs thereof, the compound of formula-1 is further represented by the following structural formula:
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公开(公告)号:US20180312538A1
公开(公告)日:2018-11-01
申请号:US15770118
申请日:2016-10-20
摘要: The present invention is relates to an improved process for the preparation (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabi-cyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone of formula I.
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