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1.发明申请ISATIN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS 有权ISATIN化合物，用于治疗变应性疾病和疾病的组合物和方法公开(公告)号：US20140275075A1
公开(公告)日：2014-09-18
申请号：US13798383
申请日：2013-03-13
Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Inventor： Craig C. BEESON , Christopher C. LINDSEY , Yuri K. PETERSON , Baerbel ROHRER
IPC: C07D209/36 , C07D403/06 , C07D401/06
CPC classification number: C07D401/06 , C07D209/34 , C07D209/36 , C07D209/38 , C07D401/04 , C07D403/04 , C07D403/06
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
Abstract translation: 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗退行性疾病和病症。
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Patent Agency Ranking
2.发明申请公开(公告)号：US20170121353A1
公开(公告)日：2017-05-04
申请号：US15407748
申请日：2017-01-17
Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Inventor： Craig C. Beeson , Christopher C. Lindsey , Yuri K. PETERSON , Baerbel Rohrer
IPC: C07F7/08 , C07D401/14 , C07D403/06 , C07D401/04
CPC classification number: C07F7/0814 , C07D231/14 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07F7/10
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
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公开(公告)号：US20140024677A1
公开(公告)日：2014-01-23
申请号：US13859546
申请日：2013-04-09
Applicant: MUSC Foundation For Research Development
Inventor： Rick G. SCHNELLMANN , Craig C. BEESON , Yuri K. PETERSON
IPC: A61K31/4704 , A61K31/138 , A61K31/137
CPC classification number: A61K31/4704 , A61K31/137 , A61K31/138 , A61K31/167
Abstract: Methods and compositions for inducing mitochondrial biogenesis are provided. In some aspects, methods for the treatment of diseases such as acute kidney disease (AKI) or a muscle wasting disease by administering tomoxetine, nisoxetine, fenoterol, formoterol, or procaterol to an individual are provided.
Abstract translation: 提供了诱导线粒体生物发生的方法和组合物。 在一些方面，提供了通过向个体施用托莫西汀，尼索西汀，非诺特罗，福莫特罗或丙卡特罗来治疗诸如急性肾脏疾病（AKI）或肌肉消瘦疾病的疾病的方法。
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4.发明申请THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS 有权噻唑化合物，治疗变应性疾病和疾病的组合物和方法公开(公告)号：US20160130241A1
公开(公告)日：2016-05-12
申请号：US14995803
申请日：2016-01-14
Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Inventor： Craig C. BEESON , Christopher C. LINDSEY , Yuri K. PETERSON , Baerbel ROHRER
IPC: C07D277/56 , C07D417/04
CPC classification number: C07D277/56 , C07D417/04
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
Abstract translation: 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗退行性疾病和病症。
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5.发明申请THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS 审中-公开噻唑化合物，治疗变应性疾病和疾病的组合物和方法公开(公告)号：US20140275178A1
公开(公告)日：2014-09-18
申请号：US13798421
申请日：2013-03-13
Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Inventor： Craig C. BEESON , Christopher C. LINDSEY , Yuri K. PETERSON , Baerbel ROHRER
IPC: C07D277/56 , C07D417/04
CPC classification number: C07D277/56 , C07D417/04
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
Abstract translation: 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗退行性疾病和病症。
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6.发明申请PYRAZOLE COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS 有权吡唑化合物，组合物和治疗变应性疾病和疾病的方法公开(公告)号：US20140274950A1
公开(公告)日：2014-09-18
申请号：US13798394
申请日：2013-03-13
Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Inventor： Craig C. BEESON , Christopher C. LINDSEY , Yuri K. PETERSON , Baerbel ROHRER
IPC: C07D403/06 , C07D403/04 , C07F7/10
CPC classification number: C07F7/0814 , C07D231/14 , C07D401/04 , C07D401/06 , C07D401/14 , C07D403/04 , C07D403/06 , C07F7/10
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
Abstract translation: 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗退行性疾病和病症。
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