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    OPTICAL COHERENCE TOMOGRAPHY FOR BIOLOGICAL IMAGING
    4.
    发明申请
    OPTICAL COHERENCE TOMOGRAPHY FOR BIOLOGICAL IMAGING 有权
    光学相关图像生物成像

    公开(公告)号：US20100305452A1

    公开(公告)日：2010-12-02

    申请号：US12790703

    申请日：2010-05-28

    申请人： John F. Black ,  Maegan K. Spencer ,  Michael Zung ,  Charles W. McNall ,  Evangeline Lumabas ,  Michael H. Rosenthal ,  John B. Simpson

    发明人： John F. Black ,  Maegan K. Spencer ,  Michael Zung ,  Charles W. McNall ,  Evangeline Lumabas ,  Michael H. Rosenthal ,  John B. Simpson

    IPC分类号： A61B6/00

    CPC分类号： A61B5/6852 ,  A61B5/0066

    摘要： Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.

    摘要翻译： 这里描述的是用于光学相干断层扫描（OCT）的导管，其包括具有第一折射率的光纤芯和具有第二折射率的界面介质，其中第一和第二折射率不匹配，使得接收电子器件被配置为接收 从参考接口和目标反射的光辐射在总噪声范围内工作，该噪声范围在散粒噪声极限的5 dB以内。 这些OCT导管可以包括具有嵌入在界面介质中的反射涂层的硅模镜。 光纤可以固定在导管的远端处，并且可以在附接到导管主体的近端的手柄内管理，并且被配置为允许导管主体和光纤相对的两个旋转 到处理。

    OCT CATHETER WITH LOW REFRACTIVE INDEX OPTICAL MATERIAL
    5.
    发明公开
    OCT CATHETER WITH LOW REFRACTIVE INDEX OPTICAL MATERIAL 审中-公开

    公开(公告)号：US20230141567A1

    公开(公告)日：2023-05-11

    申请号：US17920654

    申请日：2021-04-22

    申请人： John B. Simpson ,  Kin Foong Chan ,  Simpson Interventions, Inc.

    发明人： John B. Simpson ,  Kin Foong Chan ,  Wendy Lam ,  Sergio Salinas ,  Evangeline Lumabas

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0066 ,  A61B5/0084 ,  A61B5/6876

    摘要： Embodiments of the disclosure include apparatuses, systems, and methods for a catheter with a single element for both imaging and interventions. The catheter may have a distal tip which is positionable in a patient (e.g., in a lumen of a vessel). The distal tip may have an optical component which includes both a reflecting surface and a tapered distal end. The reflecting surface may redirect light (e.g., light received along an optical fiber of the catheter) into an imaging beam, which may be directed to a wall of the vessel. The tapered distal end may be a crossing tool used to cross an occluded or partially-occluded section of the vessel. In some embodiments, the reflecting surface and tapered distal end may be the same surface of the optical component. A low refractive index optical filler may be provided to reduce image artifacts at the imaging interface with the patient's fluid and tissue.