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9 条记录 (耗时 0.05 秒)

    Controlled- or delayed-release forms of topiramate
    4.
    发明授权
    Controlled- or delayed-release forms of topiramate 有权
    托吡酯的受控或延迟释放形式

    公开(公告)号：US06699840B2

    公开(公告)日：2004-03-02

    申请号：US10295995

    申请日：2002-11-18

    申请人： Örn Almarsson ,  Julius F. Remenar ,  Matthew L. Peterson

    发明人： Örn Almarsson ,  Julius F. Remenar ,  Matthew L. Peterson

    IPC分类号： A01N4304

    CPC分类号： A61K9/1652 ,  A61K9/0014 ,  A61K9/0019 ,  A61K47/10 ,  A61K47/32 ,  C07H5/04 ,  C07H5/06

    摘要： The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containing the same. In particular, the invention encompasses pharmaceutically acceptable salts of topiramate, including without limitation topiramate sodium, topiramate lithium, topiramate potassium, or polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, and amorphous forms thereof. The invention further encompasses novel co-crystals or complexes of topiramate, as well as pharmaceutical compositions comprising them. The invention also encompasses methods of treating or preventing a variety of diseases and conditions including, but not limited to, seizures, epileptic conditions, tremors, cerebral function disorders, obesity, neuropathic pain, affective disorders, tobacco cessation, migraines, and cluster headache.

    摘要翻译： 本发明包括托吡酯及其药学上可接受的多晶型物，溶剂合物，水合物，脱水剂，共晶体，无水或无定形形式的新型盐以及含有该盐的药物组合物和药物单位剂型。 特别地，本发明包括托吡酯的药学上可接受的盐，包括但不限于托吡酯钠，托吡酯锂，托吡酯钾或多晶型物，溶剂合物，水合物，脱水剂，共晶体，无水和无定形形式。 本发明还包括托吡酯的新型共晶体或络合物，以及包含它们的药物组合物。 本发明还包括治疗或预防各种疾病和病症的方法，包括但不限于癫痫发作，癫痫病症，震颤，脑功能障碍，肥胖症，神经性疼痛，情感障碍，戒烟，偏头痛和丛集性头痛。

    Topiramate sodium trihydrate
    7.
    发明授权
    Topiramate sodium trihydrate 有权
    托吡酯三水合物

    公开(公告)号：US06559293B1

    公开(公告)日：2003-05-06

    申请号：US10232589

    申请日：2002-09-03

    申请人： Örn Almarsson ,  Jules Remenar ,  Matthew L. Peterson

    发明人： Örn Almarsson ,  Jules Remenar ,  Matthew L. Peterson

    IPC分类号： C07H504

    CPC分类号： A61K9/1652 ,  A61K9/0014 ,  A61K9/0019 ,  A61K47/10 ,  A61K47/32 ,  C07H5/04 ,  C07H5/06

    摘要： The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containing the same. In particular, the invention encompasses pharmaceutically acceptable salts of topiramate, including without limitation topiramate sodium, topiramate lithium, topiramate potassium, or polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, and amorphous forms thereof. The invention further encompasses novel co-crystals or complexes of topiramate, as well as pharmaceutical compositions comprising them. The invention also encompasses methods of treating or preventing a variety of diseases and conditions including, but not limited to, seizures, epileptic conditions, tremors, cerebral function disorders, obesity, neuropathic pain, affective disorders, tobacco cessation, migraines, and cluster headache.

    摘要翻译： 本发明包括托吡酯及其药学上可接受的多晶型物，溶剂合物，水合物，脱水剂，共晶体，无水或无定形形式的新型盐以及含有该盐的药物组合物和药物单位剂型。 特别地，本发明包括托吡酯的药学上可接受的盐，包括但不限于托吡酯钠，托吡酯锂，托吡酯钾或多晶型物，溶剂合物，水合物，脱水剂，共晶体，无水和无定形形式。 本发明还包括托吡酯的新型共晶体或络合物，以及包含它们的药物组合物。 本发明还包括治疗或预防各种疾病和病症的方法，包括但不限于癫痫发作，癫痫病症，震颤，脑功能障碍，肥胖症，神经性疼痛，情感障碍，戒烟，偏头痛和丛集性头痛。

    Topiramate salts and compositions comprising and methods of making and using the same
    9.
    发明授权
    Topiramate salts and compositions comprising and methods of making and using the same 有权
    托吡酯盐和组合物及其制备和使用方法

    公开(公告)号：US07351695B2

    公开(公告)日：2008-04-01

    申请号：US10716976

    申请日：2003-11-19

    申请人： Öm Almarssoo ,  Jules Remenar ,  Matthew L. Peterson

    发明人： Öm Almarssoo ,  Jules Remenar ,  Matthew L. Peterson

    IPC分类号： A01N43/04 ,  A61K31/70 ,  A61K9/24

    CPC分类号： A61K9/1652 ,  A61K9/0014 ,  A61K9/0019 ,  A61K47/10 ,  A61K47/32 ,  C07H5/04 ,  C07H5/06

    摘要： The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as pharmaceutical compositions and pharmaceutical unit dosage forms containing the same. In particular, the invention encompasses pharmaceutically acceptable salts of topiramate, including without limitation topiramate sodium, topiramate lithium, topiramate potassium, or polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, and amorphous forms thereof. The invention further encompasses novel co-crystals or complexes of topiramate, as well as pharmaceutical compositions comprising them. The invention also encompasses methods of treating or preventing a variety of diseases and conditions including, but not limited to, seizures, epileptic conditions, tremors, cerebral function disorders, obesity, neuropathic pain, affective disorders, tobacco cessation, migraines, and cluster headache.

    摘要翻译： 本发明包括托吡酯及其药学上可接受的多晶型物，溶剂合物，水合物，脱水剂，共晶体，无水或无定形形式的新型盐以及含有该盐的药物组合物和药物单位剂型。 特别地，本发明包括托吡酯的药学上可接受的盐，包括但不限于托吡酯钠，托吡酯锂，托吡酯钾或多晶型物，溶剂合物，水合物，脱水剂，共晶体，无水和无定形形式。 本发明还包括托吡酯的新型共晶体或络合物，以及包含它们的药物组合物。 本发明还包括治疗或预防各种疾病和病症的方法，包括但不限于癫痫发作，癫痫病症，震颤，脑功能障碍，肥胖症，神经性疼痛，情感障碍，戒烟，偏头痛和丛集性头痛。