-
公开(公告)号：US08105833B2
公开(公告)日：2012-01-31
申请号：US12535576
申请日：2009-08-04
CPC分类号： C12N5/0062 , C12N2501/385 , C12N2501/999 , C12N2506/00
摘要： A method for forming an organ and/or tissue from undifferentiated cells derived from a vertebrate animal in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid X receptor ligand (e.g., a retinoic acid X receptor agonist or antagonist), and a method for forming a pancreas from undifferentiated cells derived from a vertebrate animal in vitro or a method for forming a tissue having morphology and function of a pancreas from undifferentiated cells derived from a vertebrate in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid receptor ligand, together with activin, that does not substantially bind to the retinoic acid receptor subtype γ.
摘要翻译： 一种用于从体外衍生自脊椎动物的未分化细胞形成器官和/或组织的方法，其包括在视黄酸X受体配体（例如视黄酸）存在下培养源自脊椎动物的未分化细胞的步骤 酸X受体激动剂或拮抗剂）以及从体外衍生自脊椎动物的未分化细胞形成胰腺的方法或用于从体外衍生自脊椎动物的未分化细胞形成具有胰腺形态和功能的组织的方法，其中 包括在视黄酸受体配体存在下培养源自脊椎动物的未分化细胞与活化素一起基本上不结合视黄酸受体亚型γ的步骤。
-
公开(公告)号：US20070161105A1
公开(公告)日：2007-07-12
申请号：US10549816
申请日：2004-03-17
CPC分类号： C12N5/0062 , C12N2501/385 , C12N2501/999 , C12N2506/00
摘要： A method for forming an organ and/or tissue from undifferentiated cells derived from a vertebrate animal in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid X receptor ligand (e.g., a retinoic acid X receptor agonist or antagonist), and a method for forming a pancreas from undifferentiated cells derived from a vertebrate animal in vitro or a method for forming a tissue having morphology and function of a pancreas from undifferentiated cells derived from a vertebrate in vitro, which comprises the step of culturing the undifferentiated cells derived from a vertebrate animal in the presence of a retinoic acid receptor ligand, together with activin, that does not substantially bind to the retinoic acid receptor subtype γ.
摘要翻译： 一种用于从体外衍生自脊椎动物的未分化细胞形成器官和/或组织的方法，其包括在视黄酸X受体配体（例如，视黄酸）存在下培养源自脊椎动物的未分化细胞的步骤 酸X受体激动剂或拮抗剂）以及从体外衍生自脊椎动物的未分化细胞形成胰腺的方法或用于从体外衍生自脊椎动物的未分化细胞形成具有胰腺形态和功能的组织的方法，其中 包括在视黄酸受体配体存在下培养来源于脊椎动物的未分化细胞以及基本上不与维甲酸受体亚型γ结合的激活素的步骤。
-
搜索结果
2 条记录 (耗时 0.016 秒)