公开(公告)号：US20170189537A1

公开(公告)日：2017-07-06

申请号：US15463698

申请日：2017-03-20

申请人： Mallinckrodt Pharma IP Trading D.A.C.

发明人： Richard I. Senderoff ,  Jeffrey D. Meyer ,  Emily N. Rollins ,  Steven D. Hughes ,  Richard M. Garcia ,  Paul D. Bishop ,  Gerald W. Lasser

IPC分类号： A61K47/42 ,  A61K9/06 ,  A61K47/32 ,  A61K9/00 ,  A61K38/48 ,  A61K47/38

CPC分类号： A61K47/42 ,  A61K9/0024 ,  A61K9/06 ,  A61K38/4833 ,  A61K47/10 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  C12Y304/21005 ,  Y10T428/2982

摘要： Provided herein are hemostatic compositions. In one embodiment, the hemostatic composition includes cross-linked polymer microspheres, such as cross-linked gelatin microspheres with pores. In another embodiment, the hemostatic composition comprises an additive such as a wetting agent, a suspending agent, or both. The hemostatic compositions may also include a hemostatic agent such as thrombin, and may include a high concentration of thrombin. The hemostatic compositions may also include plasma. Also provided herein are devices for dispersing said hemostatic compositions in a diluent, and delivering said dispersed hemostatic composition. The hemostatic compositions may also fabricated with a selected geometry as administration suggests.

公开(公告)号：US20170189538A1

公开(公告)日：2017-07-06

申请号：US15463715

申请日：2017-03-20

申请人： Mallinckrodt Pharma IP Trading D.A.C.

发明人： Richard I. Senderoff ,  Jeffrey D. Meyer ,  Emily N. Rollins ,  Steven D. Hughes ,  Richard M. Garcia ,  Paul D. Bishop ,  Gerald W. Lasser

IPC分类号： A61K47/42 ,  A61K9/06 ,  A61K38/48 ,  A61K47/38 ,  A61K47/10

CPC分类号： A61K47/42 ,  A61K9/0024 ,  A61K9/06 ,  A61K38/4833 ,  A61K47/10 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  C12Y304/21005 ,  Y10T428/2982

摘要： Provided herein are hemostatic compositions. In one embodiment, the hemostatic composition includes cross-linked polymer microspheres, such as cross-linked gelatin microspheres with pores. In another embodiment, the hemostatic composition comprises an additive such as a wetting agent, a suspending agent, or both. The hemostatic compositions may also include a hemostatic agent such as thrombin, and may include a high concentration of thrombin. The hemostatic compositions may also include plasma. Also provided herein are devices for dispersing said hemostatic compositions in a diluent, and delivering said dispersed hemostatic composition. The hemostatic compositions may also fabricated with a selected geometry as administration suggests.