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    Candida isoleucyl-tRNA synthetase proteins, nucleic acids and strains comprising same
    1.
    发明授权
    Candida isoleucyl-tRNA synthetase proteins, nucleic acids and strains comprising same 失效
    念珠菌异亮氨酰-tRNA合成酶蛋白，核酸和包含其的菌株

    公开(公告)号：US5885815A

    公开(公告)日：1999-03-23

    申请号：US742026

    申请日：1996-11-01

    申请人： Mandana Sassanfar ,  Christoph Kaufmann ,  Paul L. Gallant ,  Janice E. Kranz ,  Fariba Houman

    发明人： Mandana Sassanfar ,  Christoph Kaufmann ,  Paul L. Gallant ,  Janice E. Kranz ,  Fariba Houman

    IPC分类号： C12N9/00 ,  C07H21/04 ,  C12N1/14 ,  C12N15/00

    CPC分类号： C12N9/93

    摘要： The present invention relates to isolated and/or recombinant nucleic acids which encode Candida isoleucyl-tRNA synthetases, portions thereof, or fusion proteins comprising a Candida isoleucyl-tRNA synthetase or portion thereof. Also disclosed are constructs comprising the nucleic acids of the present invention, host cells comprising a recombinant nucleic acid or construct, and methods of producing a Candida isoleucyl-tRNA synthetase, portion thereof, or fusion protein comprising same. Also described are tester strains, which are cells engineered to rely on the function of a Candida isoleucyl-tRNA synthetase or functional fragment thereof encoded by an introduced cloned gene, and which can be used in a method of detecting an inhibitor of Candida isoleucyl-tRNA synthetase function.The invention further relates to isolated and/or recombinant Candida isoleucyl-tRNA synthetases, portions thereof, or fusion proteins comprising a Candida isoleucyl-tRNA synthetase or portion thereof, methods of use of these polypeptides in an assay to identify inhibitors of Candida isoleucyl-tRNA synthetase function, and antibodies reactive with Candida isoleucyl-tRNA synthetases.

    摘要翻译： 本发明涉及编码异亮氨酸tRNA合成酶，其部分或包含异亮氨酸假丝酵母-tRNA合成酶或其部分的融合蛋白的分离和/或重组核酸。 还公开了包含本发明的核酸的构建体，包含重组核酸或构建体的宿主细胞，以及产生异亮氨酸假丝酵母-tRNA合成酶，其部分或包含其的融合蛋白的方法。 还描述了测试菌株，其是被依赖于由引入的克隆基因编码的假丝酵母异亮氨酰-tRNA合成酶或其功能片段的功能而工程化的细胞，并且其可用于检测异亮氨酸假丝酵母-tRNA抑制剂的方法 合成酶功能。 本发明还涉及分离的和/或重组的异亮氨酸假丝酵母-tRNA合成酶，其部分或包含异亮氨酸假丝酵母-tRNA合成酶或其部分的融合蛋白，在测定中使用这些多肽的鉴定方法，以鉴定异亮氨酸假丝酵母-tRNA的抑制剂 合成酶功能和与假丝酵母异亮氨酰-tRNA合成酶反应的抗体。

    Jet device for mixing fluid
    2.
    发明申请
    Jet device for mixing fluid 审中-公开
    用于混合流体的喷射装置

    公开(公告)号：US20060286905A1

    公开(公告)日：2006-12-21

    申请号：US10567785

    申请日：2004-07-13

    申请人： Markus Brockfeld ,  Christoph Kaufmann ,  Frank-Otto Goerlitz

    发明人： Markus Brockfeld ,  Christoph Kaufmann ,  Frank-Otto Goerlitz

    IPC分类号： B24B49/00

    CPC分类号： B02B3/04 ,  B02B3/00

    摘要： A grinding and/or polishing machine for grain crops such as rice, wheat or other types of grain crops, comprising a grinding rotor surrounding a sifting basket. The grinding rotor is embodied as a hollow shaft and has openings enabling air to enter the working area. The air enters the hollow shaft via an upper and a lower air inlet. The working area is defined by a vertically displaceable catchment plate on the side of the product outlet. The displaceability of said catchment plate is adjusted by a membrane drive.

    摘要翻译： 一种用于粮食作物如米，小麦或其他类型粮食作物的研磨和/或抛光机，包括围绕筛分篮的研磨转子。 研磨转子被实施为空心轴，并具有使空气进入工作区域的开口。 空气通过上部和下部空气入口进入空心轴。 工作区域由产品出口侧面的可垂直移位的集水板限定。 通过膜驱动器调节所述集水板的位移性。

    System for increasing the production of spinning machines
    3.
    发明授权
    System for increasing the production of spinning machines 失效
    增加纺纱机生产系统

    公开(公告)号：US5511371A

    公开(公告)日：1996-04-30

    申请号：US274783

    申请日：1994-07-14

    申请人： Christoph Kaufmann

    发明人： Christoph Kaufmann

    IPC分类号： D01H13/00 ,  D01H13/32 ,  D01H13/14

    CPC分类号： D01H13/32

    摘要： The system includes a control system for deriving control variables from parameters which influence the productivity of the spinning machine (RS). Besides parameters which are measured by sensors, for the purposes of the control consideration is also given to those parameters which are not measurable or measurable only with difficulty. The last-mentioned parameters are included in the control system by means of a fuzzy logic, for which purpose the control system exhibits a fuzzy controller (FC).

    摘要翻译： 该系统包括用于从影响纺纱机（RS）的生产率的参数中导出控制变量的控制系统。 除了由传感器测量的参数之外，为了控制考虑的目的，还给出了难以测量或可测量的那些参数。 最后提到的参数通过模糊逻辑包括在控制系统中，为此，控制系统显示出模糊控制器（FC）。

    Laboratory sample transfer apparatus with interchangeable tools
    6.
    发明申请
    Laboratory sample transfer apparatus with interchangeable tools 审中-公开

    公开(公告)号：US20060085162A1

    公开(公告)日：2006-04-20

    申请号：US10965936

    申请日：2004-10-15

    申请人： Torleif Bjornson ,  Christoph Kaufmann ,  Nikolaus Ingenhoven ,  Hans-Jorg Grill

    发明人： Torleif Bjornson ,  Christoph Kaufmann ,  Nikolaus Ingenhoven ,  Hans-Jorg Grill

    IPC分类号： G06F15/00

    CPC分类号： B01L3/02 ,  B01L3/0227 ,  B01L2200/143 ,  B01L2300/023

    摘要： Apparatuses for and a method of transferring an assay protocol developed with an operator carried, hand held sample transfer tool to a robotic sample processor of a laboratory workstation are disclosed. The method comprises the execution of an assay protocol with a sample transfer apparatus (1), comprising a laboratory working area (2) with a first position retrieval system (3); a hand held sample transfer tool (10) with an active tool piece (5), which is manually carried by an operator (11); and a data processing unit (6) comprising a calculator (7), a memory (8), and a display (9); the data processing unit (6), and the first position retrieval system (3) being in communication connection with each other. The method also comprises detection of the actual position of the active tool piece (5) at every assay protocol step with the first position retrieval system (3) of the laboratory working area (2) in at least one of the X, Y, and Z directions of a 2-D or 3-D coordinate system and storing these data as a position data set. The method in addition comprises detection of all individual protocol parameters at every assay protocol step as a parameter data set and adding this parameter data set to the position data set, thereby creating a position/parameter data set. The method further comprises processing of all position/parameter data sets of the assay protocol as a virtual protocol and storing this virtual assay protocol with the data processing unit (6); and loading of the virtual assay protocol into the data processing unit of the laboratory workstation and attaching the hand held sample transfer tool or its basic components to the robotic sample processor of the laboratory workstation. The virtual assay protocol then can be manually executed at other places or automatically executed with the robotic sample processor of the laboratory workstation.