利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

103 条记录 (耗时 0.026 秒)

    CONTROL OF THE DEGRADATION OF BIODEGRADABLE IMPLANTS USING A COATING
    1.
    发明申请
    CONTROL OF THE DEGRADATION OF BIODEGRADABLE IMPLANTS USING A COATING 审中-公开
    使用涂层控制生物可降解植入物的降解

    公开(公告)号：US20090208555A1

    公开(公告)日：2009-08-20

    申请号：US10596791

    申请日：2004-09-07

    申请人： Marc Kuttler ,  Claus Harder ,  Carsten Momma ,  Heinz Mueller ,  Daniel Lootz

    发明人： Marc Kuttler ,  Claus Harder ,  Carsten Momma ,  Heinz Mueller ,  Daniel Lootz

    IPC分类号： A61K9/00 ,  A61P9/10

    CPC分类号： A61F2/82 ,  A61F2210/0004 ,  A61L31/10 ,  A61L31/148

    摘要： The invention relates to an endovascular implant, which is at least largely biodegradable and whose in vivo degradation can be controlled. To achieve this, the implant comprises a tubular base body, open on its end faces and consisting of at least one biodegradable material, said base body having an in vivo, location-dependent first degradation characteristic D1(x), in addition to a coating that covers the base body completely or in sections and consists of a biodegradable material, said coating having an in vivo, location-dependent second degradation characteristic D2(x). According to the invention, a location-dependent cumulative degradation characteristic D(x) in one location (x) is made up of the sum of the respective degradation characteristics D1(x) and D2(x) in said location (x) and the location-dependent cumulative degradation characteristic D(x) is predetermined by a variation of the second degradation characteristic D2(x) in such a way that the degradation in the given location (x) of the implant takes place over a predeterminable time period at a predeterminable degradation rate.

    摘要翻译： 本发明涉及一种血管内植入物，其至少在很大程度上是可生物降解的并且其体内降解可被控制。 为了实现这一点，植入物包括管状基体，其在其端面上开口并由至少一种生物可降解材料组成，所述基体除了涂层之外还具有体内位置依赖性的第一降解特性D1（x） 其完全或部分地覆盖基体，并且由可生物降解的材料组成，所述涂层具有体内位置相关的第二降解特征D2（x）。 根据本发明，一个位置（x）中的位置相关的累积退化特性D（x）由所述位置（x）中的各自的劣化特性D1（x）和D2（x）之和构成， 位置相关的累积退化特性D（x）是通过第二劣化特性D2（x）的变化来预定的，使得植入物的给定位置（x）的劣化发生在预定时间段 可预测的降解率。

    Endoprosthesis comprising a magnesium alloy
    2.
    发明申请
    Endoprosthesis comprising a magnesium alloy 审中-公开
    包含镁合金的内假体

    公开(公告)号：US20060052864A1

    公开(公告)日：2006-03-09

    申请号：US11221344

    申请日：2005-09-07

    申请人： Claus Harder ,  Marc Kuttler ,  Bodo Gerold ,  Heinz Mueller

    发明人： Claus Harder ,  Marc Kuttler ,  Bodo Gerold ,  Heinz Mueller

    IPC分类号： A61F2/06

    CPC分类号： A61L31/148 ,  A61L31/022

    摘要： An endoprosthesis, in particular an intraluminal endoprosthesis such as a stent, comprises a carrier structure, which includes at least one component comprising a magnesium alloy of the following composition: Rare earth metals: between about 2.0 and about 5.0% by weight, with neodymium between about 1.5 and about 3.0% by weight Yttrium: between about 3.5% and about 4.5% by weight Zirconium: between about 0.3% and about 1.0% by weight Balance: between 0 and about 0.5% by weight wherein magnesium occupies the proportion by weight that remains to 100% by weight in the alloy.

    摘要翻译： 内置假体，特别是管腔内假体，例如支架，包括载体结构，其包括至少一种包含以下组成的镁合金的组分：稀土金属：约2.0至约5.0重量％之间，钕在 约1.5重量％至约3.0重量％钇：约3.5重量％至约4.5重量％锆：约0.3重量％至约1.0重量％平均：0至约0.5重量％其中镁占重量的比例， 在合金中保持为100重量％。

    Method and device for crimping a stent
    3.
    发明授权
    Method and device for crimping a stent 失效
    用于压接支架的方法和装置

    公开(公告)号：US06726713B2

    公开(公告)日：2004-04-27

    申请号：US09923808

    申请日：2001-08-07

    申请人： Max Schaldach ,  Detlef Behrend ,  Klaus-Peter Schmitz ,  Heinz Mueller ,  Daniel Lootz ,  Dietmar Esperschidt

    发明人： Max Schaldach ,  Detlef Behrend ,  Klaus-Peter Schmitz ,  Heinz Mueller ,  Daniel Lootz ,  Dietmar Esperschidt

    IPC分类号： A61F206

    CPC分类号： A61F2/958 ,  A61F2002/9522

    摘要： The invention concerns a method and a device for crimping a stent onto a balloon of a balloon catheter. The stent is arranged on the balloon so that an outside surface of the balloon and an inside surface of the stent contact each other to form a combination of balloon and stent. The combination is compressed to crimp the stent onto the balloon. The invention is distinguished in that the combination is compressed to varying degrees along the longitudinal axis of the combination.

    摘要翻译： 本发明涉及一种用于将支架卷曲到球囊导管的球囊上的方法和装置。 支架布置在气囊上，使得球囊的外表面和支架的内表面彼此接触以形成球囊和支架的组合。 将组合物压缩以将支架卷曲到气球上。 本发明的区别在于，组合沿着组合的纵向轴线被不同程度地压缩。

    Stent
    4.
    发明授权
    Stent 失效
    支架

    公开(公告)号：US06896695B2

    公开(公告)日：2005-05-24

    申请号：US09804975

    申请日：2001-03-13

    申请人： Heinz Mueller ,  Claus Harder

    发明人： Heinz Mueller ,  Claus Harder

    IPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2/06

    CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558

    摘要： A stent, in particular a coronary stent, comprising at least two tubular portions which are arranged adjacently in the longitudinal direction of the stent and which comprise a plurality of interconnected, substantially cell-shaped elements which have an orientation and are connected together in the longitudinal direction of the stent by way of at least one first connecting means, wherein the elements are of such an arrangement and/or configuration that the ends of the elements which are in the longitudinal direction of the stent define an edge contour extending around the stent in a wave-like configuration in the peripheral direction thereof, and wherein the mutually adjoining edge contours of two tubular portions extend around the stent substantially in in-phase relationship.

    摘要翻译： 一种支架，特别是冠状支架，包括至少两个管状部分，其沿着支架的纵向方向相邻布置并且包括多个相互连接的基本上为细胞形状的元件，其具有取向并且在纵向方向上连接在一起 支架的方向通过至少一个第一连接装置，其中元件具有这样的布置和/或构造，使得沿着支架的纵向方向的元件的端部限定围绕支架延伸的边缘轮廓 沿圆周方向的波状构造，并且其中两个管状部分的相互邻接的边缘轮廓基本上以相位相位延伸围绕支架延伸。

    Implant of low radial strength
    9.
    发明申请
    Implant of low radial strength 有权
    植入物径向强度低

    公开(公告)号：US20060064160A1

    公开(公告)日：2006-03-23

    申请号：US11222595

    申请日：2005-09-09

    申请人： Bodo Gerold ,  Claus Harder ,  Bernd Heublein ,  Heinz Mueller ,  Eva Heublein ,  Nora Heublein ,  Christoph Heublein

    发明人： Bodo Gerold ,  Claus Harder ,  Bernd Heublein ,  Heinz Mueller ,  Eva Heublein ,  Nora Heublein ,  Christoph Heublein

    IPC分类号： A61F2/06

    CPC分类号： A61F2/86 ,  A61F2/90 ,  A61F2/91 ,  A61L31/022

    摘要： The invention concerns an endovascular implant comprising a biodegradable material and having a tubular main body which is open at the ends and which is dilatable from an unexpanded condition into an expanded condition. The implant is so designed that when the implant in the expanded condition is subjected to a radially acting compression pressure in the range of between 5 and 30 kPa (0.05-0.3 bar) a cross-sectional area of the implant is reduced to 70% or less of the original cross-sectional area, or an internal volume of the implant is reduced to 70% or less of the original internal volume.

    摘要翻译： 本发明涉及一种包括可生物降解材料的血管内植入物，并且具有管状主体，该管状主体在端部处是开口的，并且可从未膨胀状态扩张到膨胀状态。 植入物的设计使得当处于膨胀状态的植入物经受5至30kPa（0.05-0.3巴）范围内的径向作用压缩压力时，植入物的横截面面积减小至70％或 较小的原始横截面积或植入物的内部体积减少到原始内部体积的70％或更小。