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1.发明授权Multi-stream data collection system for noninvasive measurement of blood constituents 有权用于非侵入性测量血液成分的多流数据收集系统公开(公告)号：US09277880B2
公开(公告)日：2016-03-08
申请号：US12829352
申请日：2010-07-01
申请人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B5/1455 , A61B5/145 , A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
摘要翻译： 本公开涉及用于测量各种血液成分或分析物（例如葡萄糖）的非侵入性方法，装置和系统。 在一个实施例中，光源包括LED和超发光LED。 光源发射至少约1610nm，约1640nm和约1665nm的波长的光。 在一个实施例中，检测器包括以特殊几何形状布置的多个光电检测器，其包括基本上线性的基本相等的间隔几何形状，基本上线性的基本上不等间隔的几何形状以及基本上网格的几何形状。
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公开(公告)号：US08570503B2
公开(公告)日：2013-10-29
申请号：US13525166
申请日：2012-06-15
申请人： Hung Vo , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Hung Vo , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： G01J1/42
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a heat sink that can direct heat away from the light source.
摘要翻译： 用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括可以将热量从光源引导出来的散热器。
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3.发明申请MULTI-STREAM DATA COLLECTION SYSTEM FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS 审中-公开多流量数据采集系统用于非血液测量血液成分公开(公告)号：US20100030040A1
公开(公告)日：2010-02-04
申请号：US12534827
申请日：2009-08-03
申请人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Jeroen Poeze , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
摘要翻译： 本公开涉及用于测量各种血液成分或分析物（例如葡萄糖）的非侵入性方法，装置和系统。 在一个实施例中，光源包括LED和超发光LED。 光源发射至少约1610nm，约1640nm和约1665nm的波长的光。 在一个实施例中，检测器包括以特殊几何形状布置的多个光电检测器，其包括基本上线性的基本相等的间隔几何形状，基本上线性的基本上不等间隔的几何形状以及基本上网格的几何形状。
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公开(公告)号：US20120253150A1
公开(公告)日：2012-10-04
申请号：US13525166
申请日：2012-06-15
申请人： Sean Merritt , Marcelo Lamego , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Sean Merritt , Marcelo Lamego , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B6/00 , A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to a sensor having a set of photodetectors that are arranged at various locations to enable the measurement of blood glucose. The photodetectors are arranged across multiple locations. For example, the detector may comprise multiple photodetector arrays that are arranged to have a sufficient difference in mean path length to allow for noise cancellation and noise reduction. Walls may be used in the detector to separate individual photodetectors and prevent mixing of detected optical radiation between the different locations on the measurement site. A window may also be employed to facilitate the passing of optical radiation at various wavelengths for measuring glucose in the tissue.
摘要翻译： 本公开涉及具有一组光电检测器的传感器，其被布置在各种位置以能够测量血糖。 光电探测器布置在多个位置。 例如，检测器可以包括多个光电检测器阵列，其布置成在平均路径长度上具有足够的差异以允许噪声消除和降噪。 可以在检测器中使用壁来分离各个光电检测器，并防止检测的光辐射在测量位置上的不同位置之间的混合。 还可以使用窗口来促进用于测量组织中葡萄糖的各种波长的光辐射的通过。
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公开(公告)号：US08203704B2
公开(公告)日：2012-06-19
申请号：US12534823
申请日：2009-08-03
申请人： Sean Merritt , Marcelo Lamego , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Sean Merritt , Marcelo Lamego , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： G01J1/42
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to a sensor having a set of photodetectors that are arranged at various locations to enable the measurement of blood glucose. The photodetectors are arranged across multiple locations. For example, the detector may comprise multiple photodetector arrays that are arranged to have a sufficient difference in mean path length to allow for noise cancellation and noise reduction. Walls may be used in the detector to separate individual photodetectors and prevent mixing of detected optical radiation between the different locations on the measurement site. A window may also be employed to facilitate the passing of optical radiation at various wavelengths for measuring glucose in the tissue.
摘要翻译： 本公开涉及具有一组光电检测器的传感器，其被布置在各种位置以能够测量血糖。 光电探测器布置在多个位置。 例如，检测器可以包括多个光电检测器阵列，其布置成在平均路径长度上具有足够的差异以允许噪声消除和降噪。 可以在检测器中使用壁来分离各个光电检测器，并防止检测的光辐射在测量位置上的不同位置之间的混合。 还可以使用窗口来促进用于测量组织中葡萄糖的各种波长的光辐射的通过。
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公开(公告)号：USD621516S1
公开(公告)日：2010-08-10
申请号：US29323409
申请日：2008-08-25
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公开(公告)号：US20100030041A1
公开(公告)日：2010-02-04
申请号：US12534825
申请日：2009-08-03
申请人： Johannes Bruinsma , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Johannes Bruinsma , Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to an emitter that is suitable for a noninvasive blood constituent sensor. The emitter is configured as a point optical source that comprises a plurality of LEDs that emit a sequence of pulses of optical radiation across a spectrum of wavelengths. In some embodiments, the plurality of sets of optical sources may each comprise at least one top-emitting LED and at least one super luminescent LED. In some embodiments, the emitter comprises optical sources that transmit optical radiation in the infrared or near-infrared wavelengths suitable for detecting glucose. In order to achieve the desired SNR for detecting analytes like glucose, the emitter may be driven using a progression from low power to higher power. In addition, the emitter may have its duty cycle modified to achieve a desired SNR.
摘要翻译： 本发明涉及适用于无创血液成分传感器的发射器。 发射器被配置为点光源，其包括发射穿过波长频谱的光辐射的脉冲序列的多个LED。 在一些实施例中，多组光源可以各自包括至少一个顶部发射LED和至少一个超级发光LED。 在一些实施例中，发射器包括透射适合于检测葡萄糖的红外或近红外波长的光辐射的光源。 为了实现用于检测诸如葡萄糖的分析物的期望的SNR，可以使用从低功率到较高功率的进程来驱动发射器。 此外，发射器可以修改其占空比以实现期望的SNR。
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8.发明申请MULTI-STREAM SENSOR FRONT ENDS FOR NONINVASIVE MEASUREMENT OF BLOOD CONSTITUENTS 有权多流量传感器前端用于非血液测量血液成分公开(公告)号：US20100030039A1
公开(公告)日：2010-02-04
申请号：US12534812
申请日：2009-08-03
申请人： Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
发明人： Marcelo Lamego , Sean Merritt , Cristiano Dalvi , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B5/14552 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B2562/0233 , A61B2562/04 , A61B2562/046 , A61B2562/146
摘要： The present disclosure relates to an interface for a noninvasive glucose sensor that comprises a front-end adapted to receive an input signals from optical detectors and provide corresponding digital signals. In one embodiment, the front-end comprises switched capacitor circuits that are capable of handling multiple streams signals from the optical detectors. In another embodiment, the front-end comprises transimpedance amplifiers that are capable of handling multiple streams of input signals. In this embodiment, the transimpedance amplifier may be configured based on its own characteristics, such as its impedance, the impedance of the photodiodes to which it is coupled, and the number of photodiodes to which it is coupled.
摘要翻译： 本公开涉及一种用于非侵入式葡萄糖传感器的接口，其包括适于接收来自光学检测器的输入信号并提供相应数字信号的前端。 在一个实施例中，前端包括能够处理来自光学检测器的多个流信号的开关电容器电路。 在另一个实施例中，前端包括能够处理多个输入信号流的跨阻放大器。 在该实施例中，跨阻抗放大器可以基于其自身的特性，例如其阻抗，与其耦合的光电二极管的阻抗以及与其耦合的光电二极管的数量来配置。
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9.发明申请CONTOURED PROTRUSION FOR IMPROVING SPECTROSCOPIC MEASUREMENT OF BLOOD CONSTITUENTS 有权用于改善血液成分的光谱测量的轮廓推测公开(公告)号：US20100010326A1
公开(公告)日：2010-01-14
申请号：US12497523
申请日：2009-07-02
申请人： Cristiano Dalvi , Marcelo Lamego , Sean Merritt , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
发明人： Cristiano Dalvi , Marcelo Lamego , Sean Merritt , Hung Vo , Johannes Bruinsma , Jeroen Poeze , Ferdyan Lesmana , Greg Olsen , Massi Joe E. Kiani
IPC分类号： A61B5/1455
CPC分类号： A61B5/02427 , A61B5/02416 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14551 , A61B5/14552 , A61B5/4875 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6843 , A61B5/70 , A61B5/7275 , A61B2562/146
摘要： A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.
摘要翻译： 用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。 凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。 结果，可以减少光源和光电检测器之间的光程。 此外，传感器可以包括可将热量远离光源引导的散热器。 此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。 屏蔽可以降低由光电检测器接收的噪声。
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公开(公告)号：USD606659S1
公开(公告)日：2009-12-22
申请号：US29323408
申请日：2008-08-25
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