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    High alkaline protease and use thereof
    4.
    发明授权
    High alkaline protease and use thereof 失效
    高碱性蛋白酶及其用途

    公开(公告)号：US08153413B2

    公开(公告)日：2012-04-10

    申请号：US11719713

    申请日：2005-11-16

    申请人： Jie Lu ,  Zhi jun Li ,  Si Hung Vo ,  Yuji Hatada ,  Ken Takai ,  Susumu Ito ,  Koki Horikoshi

    发明人： Jie Lu ,  Zhi jun Li ,  Si Hung Vo ,  Yuji Hatada ,  Ken Takai ,  Susumu Ito ,  Koki Horikoshi

    IPC分类号： C12N9/00 ,  C12N9/92 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

    CPC分类号： C12N9/52

    摘要： The invention aims to provide a novel alkaline protease having peculiar properties such as high alkali activity, resistance to surfactants and calcium-dependent thermostability and exhibiting excellent performance in highly alkaline detergents, and a gene coding for the amino acid sequence thereof. There is provided an alkaline protease with such properties that an active pH range is from 5 to 13, an optimum pH is approximately 12.6, an optimum temperature is 70° C., no activity drop by heating is observed up to 65° C. at pH 10 and the optimum temperature and the thermostability are not affected by Ca2+ ions. Specifically, there is provided, for example, an alkaline protease having an amino acid sequence constituting a mature enzyme as represented by SEQ ID NO: 3 or an amino acid sequence resulting from deletion, substitution, situs inversus arrangement, addition or insertion of a part of amino acids thereof, or derived from Alkaliphillus transvaalensis. The protease cleaves 26 peptide bonds among 29 peptide bonds of acidic insulin B-chain.

    摘要翻译： 本发明的目的在于提供一种具有高碱性，耐表面活性和钙依赖性热稳定性等特性，在高碱性洗涤剂中表现出优异性能的新型碱性蛋白酶及其氨基酸序列的编码基因。 提供了具有这样的性质的碱性蛋白酶，其活性pH范围为5至13，最佳pH为约12.6，最适温度为70℃，在65℃下不观察到加热下的活性降低 pH 10，最佳温度和热稳定性不受Ca2 +离子的影响。 具体地，例如提供了具有SEQ ID NO：3所示的构成成熟酶的氨基酸序列的氨基酸序列的碱性蛋白酶或由缺失，取代，位置反转排列，添加或插入部分 的氨基酸，或衍生自变形白菜（Alkaliphillus transvaalensis）。 蛋白酶在酸性胰岛素B链的29个肽键中切割26个肽键。

    Fluid product dispensing head
    5.
    发明授权
    Fluid product dispensing head 失效
    流体产品分配头

    公开(公告)号：US07748580B2

    公开(公告)日：2010-07-06

    申请号：US10564163

    申请日：2004-07-13

    申请人： Frédéric Berthelin ,  Erwan Delisle ,  Luc Uytterhaeghe ,  Alain Huet ,  Serge Lebalc'h ,  Chi-Hung Vo

    发明人： Frédéric Berthelin ,  Erwan Delisle ,  Luc Uytterhaeghe ,  Alain Huet ,  Serge Lebalc'h ,  Chi-Hung Vo

    IPC分类号： B67D3/00

    CPC分类号： B65D47/242

    摘要： A fluid dispenser head for associating with a fluid reservoir (1), the head having: a stationary base (2) formed by, or for mounting on, the reservoir; a rotary actuator element (3) mounted in rotary manner on the base (2) so as to turn about an axis of rotation between two extreme abutment positions; and a dispenser orifice (30) that can be closed selectively by turning the element on the base. The two extreme abutment positions define two open positions of the dispenser orifice separated by at least one position in which the dispenser orifice is closed. The dispenser orifice (30) is situated on the axis of rotation of the element on the base.

    摘要翻译： 一种用于与流体储存器（1）相关联的流体分配头，该头部具有：由储存器形成或用于安装在储存器上的固定基座（2） 旋转致动器元件（3），其以旋转方式安装在所述基座（2）上，以绕两个极限邻接位置之间的旋转轴线转动; 以及可以通过在基座上转动元件而选择性地关闭的分配器孔口（30）。 两个极端邻接位置限定了分配器孔的两个打开位置，其中分配器孔被关闭的至少一个位置分开。 分配器孔口（30）位于基座上的元件的旋转轴线上。

    Fluid product dispensing head
    7.
    发明申请
    Fluid product dispensing head 失效
    流体产品分配头

    公开(公告)号：US20070017937A1

    公开(公告)日：2007-01-25

    申请号：US10564163

    申请日：2004-07-13

    申请人： Frederic Berthelin ,  Erwan Delisle ,  Luc Utterhaeghe ,  Alain Huet ,  Serge Lebalc'h ,  Chi-Hung Vo

    发明人： Frederic Berthelin ,  Erwan Delisle ,  Luc Utterhaeghe ,  Alain Huet ,  Serge Lebalc'h ,  Chi-Hung Vo

    IPC分类号： B67D3/00 ,  B67D5/06 ,  B65D47/00

    CPC分类号： B65D47/242

    摘要： A fluid dispenser head for associating with a fluid reservoir (1), said head comprising: a stationary base (2) formed by, or for mounting on, said reservoir; a rotary actuator element (3) mounted in rotary manner on the base (2) so as to turn about an axis of rotation between two extreme abutment positions; and a dispenser orifice (30) that can be closed selectively by turning the element on the base, the dispenser head being characterized in that the two extreme abutment positions define two open positions of the dispenser orifice separated by at least one position in which the dispenser orifice is closed, and in that the dispenser orifice (30) is situated on the axis of rotation of the element on the base.

    摘要翻译： 一种用于与流体储存器（1）相关联的流体分配头，所述头部包括：由所述储存器形成或用于安装在所述储存器上的固定基座（2） 旋转致动器元件（3），其以旋转方式安装在所述基座（2）上，以绕两个极限邻接位置之间的旋转轴线转动; 以及分配器孔口（30），其可以通过在所述基座上转动所述元件而选择性地关闭，所述分配器头部的特征在于，所述两个极端邻接位置限定所述分配孔的两个打开位置，所述打开位置分开至少一个位置， 孔口关闭，并且分配器孔口（30）位于基座上的元件的旋转轴线上。

    Physical layer transceiver architecture for a home network station connected to a telephone line medium
    8.
    发明授权
    Physical layer transceiver architecture for a home network station connected to a telephone line medium 失效
    连接到电话线介质的家庭网络站的物理层收发器架构

    公开(公告)号：US06771750B1

    公开(公告)日：2004-08-03

    申请号：US09181559

    申请日：1998-10-29

    申请人： Colin Nayler ,  Phil Keller ,  Oikwan Tsang ,  Hung Vo ,  Dennis Lau ,  Yi Cheng ,  Boon-Aik Ang ,  Zhen-Hua Liu

    发明人： Colin Nayler ,  Phil Keller ,  Oikwan Tsang ,  Hung Vo ,  Dennis Lau ,  Yi Cheng ,  Boon-Aik Ang ,  Zhen-Hua Liu

    IPC分类号： H04L2503

    CPC分类号： H04L12/2838 ,  H04L1/20 ,  H04L12/2803 ,  H04L2012/2845

    摘要： A physical layer transceiver of a home network station connected to a telephone medium has an architecture enabling adaptation of detection circuitry based on received network signals to enable reliable recovery of data signals. The physical layer transceiver includes an input amplifier that amplifies network signals according to one of 128 gain settings set by a receiver gain control signal. A signal conditioning circuit includes an envelope detector configured for outputting an envelope of the amplified received signal, and an energy detector configured for outputting an energy signal of the amplified received signals. The envelope signal and the energy signal are supplied to slicer threshold circuits, configured for outputting noise, peak, data event and energy event signals based on noise threshold, peak threshold, data transition threshold, and energy threshold signals, respectively. A digital controller controls the input amplifier gain and the threshold values, and adjusts the gain and threshold values based on the noise event signal and the peak event signal within an access ID (AID) interval. Hence, the receiver can be optimized on a per-packet basis for receiving network signals by adjusting the receiver portion during the AID preamble phase of the data packet. Gain control may also be used by the digital controller on the transmitter portion to selectively adjust the output gain for optimizing transmission to a destination home network station.

    摘要翻译： 连接到电话介质的家庭网络站的物理层收发器具有能够基于接收到的网络信号来适应检测电路的架构，以实现数据信号的可靠恢复。 物理层收发器包括输入放大器，其根据由接收机增益控制信号设置的128个增益设置之一放大网络信号。 信号调理电路包括被配置为输出放大的接收信号的包络的包络检测器，以及被配置为输出放大的接收信号的能量信号的能量检测器。 包络信号和能量信号被提供给限幅器阈值电路，其被配置为分别基于噪声阈值，峰值阈值，数据转换阈值和能量阈值信号输出噪声，峰值，数据事件和能量事件信号。 数字控制器控制输入放大器增益和阈值，并且基于接入ID（AID）间隔内的噪声事件信号和峰值事件信号来调整增益和阈值。 因此，可以在每个分组的基础上优化接收机，以通过在数据分组的AID前导阶段期间调整接收机部分来接收网络信号。 增益控制也可以由发射器部分上的数字控制器使用，以选择性地调整输出增益以优化到目的地家庭网络站的传输。